Thiago Carvalho @cyrilpedia@social.cleverlibre.org
I've worked on all of science, from B cells to T cells.
https://fellowsherpa.com
Joined Nov 2022
Thiago Carvalho
boosted
Elon Musk reinstates TRAITOR Michael Flynn’s acct ON JANUARY 6TH?
Thanks Elon for affirming why I killed a 125k Twitter acct.
FUCKING TRAITOR PIECES OF SHIT.
"Most relapsed/refractory large B cell lymphoma (r/rLBCL) patients receiving anti-CD19 chimeric antigen receptor (CAR19) T cells relapse. To characterize determinants of resistance, we profiled over 700 longitudinal specimens from two independent cohorts"
#CART #immunotherapy #immunology #Lymphoma #LBCL #CD19
https://www.cell.com/cancer-cell/fulltext/S1535-6108(22)00591-8?dgcid=raven_jbs_aip_email
Thiago Carvalho
boosted
Sensor #NLR #immune proteins activate #oligomerization of their NRC helpers in response to #plantpathogens
Kamoun and cowokers, The Sainsbury Lab
https://www.embopress.org/doi/full/10.15252/embj.2022111519
Tools
"Here, we describe the development and validation of a computational program, which designs strain-specific CRISPR guide RNAs that can be utilized to modify complex consortia. As a proof of concept, we applied the program to two applications: the isolation of specific microbes from consortia and the removal of specific microbes from consortia. This technique has many practical applications, including addressing the problem of antibiotic-resistant microbes and isolating useful microbes from the environment."
#CRISPR #Microbiology
"Her first stint as minister was widely hailed as a success, with Marina reducing Amazonian deforestation by as much as 70 per cent. Her administrative and financial initiatives included new management of public forests, the creation of a forest service and a biodiversity institute and several funds for the maintenance of the Amazon."
https://www.ft.com/content/53641c63-f90a-4171-902d-bf07398918d8
Kudos to Pam Belluck at the NYT for this opening paragraph - this is the right way to report on a story like lecanemab:
"The Food and Drug Administration on Friday approved a new #Alzheimer’s drug that may modestly slow the pace of cognitive decline early in the disease, but also carries risks of swelling and bleeding in the brain."
https://www.nytimes.com/2023/01/06/health/alzheimers-drug-leqembi-lecanemab.html
Thiago Carvalho
boosted
Resurrection of endogenous retroviruses during aging reinforces senescence
Thiago Carvalho
boosted
How to slow down scientific progress
"Leo Szilard—the physicist who first conceived of the nuclear chain reaction and who urged the US to undertake the Manhattan Project—also wrote fiction. His book of short stories, The Voice of the Dolphins, contains a story “The Mark Gable Foundation,” dated 1948."
You can see the full thing at this link, but I've also taken a screenshot of an excerpt. 😬 🤔 😢
@PaoloViscardi@toot.community Congratulations!
Thiago Carvalho
boosted
RT @aetarke@twitter.com
Can CD4+ T cells cross-recognize different coronaviruses (CoV), offering immune protection from potential future CoV pandemics? We explore this concept in our new study, just posted in pre-print. http://biorxiv.org/content/10.1101/2023.01.04.522794v1
@Alba_Grifoni@twitter.com @SetteLab@twitter.com 1/5
Thiago Carvalho
boosted
RT @feleszko@twitter.com
A good and robust guidance through management and #immunology of #pediatric MIS-C/PIMS by the #EAACI Immunology Section with @dekinderarts@twitter.com. https://onlinelibrary.wiley.com/doi/10.1111/pai.13900
Thiago Carvalho
boosted
Computational design of #CRISPR guide RNAs to enable strain-specific control of #microbial #consortia | PNAS
Thiago Carvalho
boosted
Last month I gave the keynote address at the Seattle Data for Policy meeting, entitled "Social media, Collective Decision-making, and the Stewardship of Global Information Flows"
It's now puiblicly available on youtube: https://www.youtube.com/watch?v=oATpDGdrTLg
Thiago Carvalho
boosted
RT @takanobu_ka
“Immotile cilia mechanically sense the direction of fluid flow for left-right determination” published in #Science #AAAS. We answered the question that "How the embryo senses nodal flow and why only the L-side cilia can respond." Let me guide you! 1/n https://www.science.org/doi/10.1126/science.abq8148
Thiago Carvalho
boosted
I'm a researcher in Mexico studying immunology. Our lab specializes in newborn immunology & T cell biology. Our approach is cellular and systems immunology.
#introduction #YoungPI #Immunology #EarlyCareer
@tomasson Hanging out with the other proboscideans.
You?
@tomasson @LockeLiberal1 Long time no see!
Thiago Carvalho
boosted
First tweet...um.. post? from mastodon! Would love to follow hematology, genetics, physiology, medicine, and Iowa folks!
Thiago Carvalho
boosted
A black man wrongfully jailed for a week in Louisiana after face recognition error, report says. Lawyer says police didn't check man's height, weight or the mole on his face.
Thiago Carvalho
boosted
Now Available: Postdoctoral Fellowship in Virus Classification and Bioinformatics
I've worked on all of science, from B cells to T cells.
https://fellowsherpa.com
Joined Nov 2022
