Thiago Carvalho @cyrilpedia@social.cleverlibre.org
I've worked on all of science, from B cells to T cells.
https://fellowsherpa.com
Joined Nov 2022
@andrewplested And thanks for the comments
@andrewplested It's a positive allosteric regulator - sorry for the confusion (I meant agonist in the sense that it activates the channel, but in the strict sense it does not mimic the natural ligand).
Thiago Carvalho
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RT @chall2023
New flyer for our Workshop in Rome! Looking forward to seeing you all in 5 days.
#rome #interdiciplinary #science
Thiago Carvalho
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Virginia Norwood, ‘Mother’ of Satellite Imaging Systems, Dies at 96
https://www.nytimes.com/2023/04/12/science/space/virginia-norwood-dead.html
Thiago Carvalho
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Postdoctoral Fellow - Furukawa Lab
#ScienceJobs #job
Cold Spring Harbor #UnitedStatesUS #PostdoctoralFellow
https://jobrxiv.org/job/cold-spring-harbor-laboratory-27778-postdoctoral-fellow-furukawa-lab/?feed_id=42318
Thiago Carvalho
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TOR acts as a metabolic gatekeeper for #auxin-dependent lateral root initiation in #Arabidopsis #thaliana
Emmanuel Gaquerel, Alexis Maizel and coworkers show that shoot-derived sugar activates #TOR signalling to initiate lateral #root formation.
https://www.embopress.org/doi/10.15252/embj.2022111273
Capt Louis is shocked. Shocked!
"The mogul’s treatment of union organizers and whistleblowers suggested that “free-speech absolutism” was mostly code for a high tolerance for bigotry toward particular groups, a smoke screen that obscured an obvious hostility toward any speech that threatened his ability to make money."
Thiago Carvalho
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What is a Biomarker? A Snippet
by Elio
Most likely, we have all run into the term "biomarker," no? So, what is a biomarker? In 1998, the NIH Biomarkers Definitions Working Group defined a biomarker as "a characteristic that is objectively measured and evaluated as an indicator of normal biological processes,...
Read more → https://schaechter.asmblog.org/schaechter/2023/04/what-is-a-biomarker-a-snippet.html
Many interesting positions open at PRBB Barcelona, tech, manager, training, postdocs - have a look 👇
#ScienceJobs
Thiago Carvalho
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.@DrJohannaRhodes explores a #PLOSBiology study of the alarming evolutionary potential of a #pandemic clone of #WheatBlast, arguing the urgent need for genomic surveillance & pre-emptive breeding of resistant wheat. Primer: https://plos.io/3MLuPay Paper: https://plos.io/3zP6Gse
Thiago Carvalho
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My latest Clinical Pipeline column for #NatureMedicine is a look at zuranolone, a new antidepressant developed by Sage & Biogen, targeting the GABA pathway.
#drugdiscovery #drugdevelopment #depression #GABA #neuroscience
"In this study, we investigated the mechanism that one specific species of microbiota shortens lifespan and disrupts gut homeostasis of the aged flies, using a “fermented” fly diet. We found that the specific effects of this bacterium on fly healthspan were due to its capability of stimulating a specific receptor in the gut that recognizes peptidoglycan, a component of bacterial cell wall. Paradoxically, the same bacterium also increases stress resistance and defence against oral infection of a pathogen."
#Drosophila #Microbiota #ageing
https://journals.plos.org/plosgenetics/article?id=10.1371/journal.pgen.1010709
Thiago Carvalho
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Quite happy to share this latest work from our lab. In this study, we have addressed an important question of general importance: if and how brain medications (such as anti-depression drugs) change brain over time. We addressed this by specifically investigating the impact of an important drug, Ketamine.
https://www.biorxiv.org/content/10.1101/2023.04.12.536506v1
#biorxiv #neuroscience #ketamine #brainplasticity
thread ....
Thiago Carvalho
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'The burden of navigating Covid’s risks now falls on the individual, and what “post-pandemic” means for one person or community, like Ninety-Fifth Street Elementary, looks wildly different than it does for others.'
Thiago Carvalho
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Philadelphia’s 'Matisse in the 1930s' show is in Paris (l’Orangerie), will open in Nice in the summer.
'The exhibition fascinates as the first ever to focus on Matisse in this decade, for its optimistic account of renewal by an artist in his sixties and for European audiences as a rare chance to encounter tremendous paintings acquired by Americans.'
https://www.ft.com/content/4a5b1c3c-9e8c-4973-8fed-5bc9b0ec055a
Thiago Carvalho
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On this #throwbackthursday we go back to our Episode #48, there we talked to Déborah Bourc'his from L'Institut Curie in Paris about her work on the role of DNA methylation in mammalian development. #epigenetics #podcast #womeninstem
Listen here: https://www.activemotif.com/podcasts#deborah-bourchis
Thiago Carvalho
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Very excited to share my PhD work on B cell responses in lung cancer!
Antibodies to endogenous retroviruses promote lung cancer immunotherapy
'Our cross-species study indicates that scaling of cell size to ploidy is not due to abrupt changes in cell division timing, that different size scaling regimes occur during embryogenesis, and that the developmental program of Xenopus is remarkably consistent across a wide range of genome and egg sizes.'
https://www.cell.com/current-biology/fulltext/S0960-9822(23)00161-6
Thiago Carvalho
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Synteny Identifies Reliable Orthologs for Phylogenomics and Comparative Genomics of the Brassicaceae https://doi.org/10.1093/gbe/evad034 #science #evolution #biology #genome #SciComm #evolgen_paper
"Reports, filed not from the trenches but from assembly lines and offices, start to speak of fragmentation, helplessness, and an imprisonment that requires no bars. A new fear wells up: a tired mind may be more resistant to healing than the body in which it is housed."
https://www.newyorker.com/magazine/2023/04/17/a-history-of-fatigue-georges-vigarello-book-review
I've worked on all of science, from B cells to T cells.
https://fellowsherpa.com
Joined Nov 2022
