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'To address this critical knowledge gap, we conducted a comprehensive cross-species analysis of transcriptomic data from over 6000 blood samples from macaques and humans infected with one of 31 viruses, including , , , , and .'

biorxiv.org/content/10.1101/20

Once someone makes the underlying assumptions explicit, you know what's coming next. Buckle up, tissue resident cell fate mapping, it's going to be a bumpy ride:

"Fate-mapping studies using conditional reporter genes and regulated expression of cre recombinase have led to the view that most resident tissue macrophage populations are established during embryonic development and maintained in the adult by self-renewal with minimal input from bone marrow progenitors or blood monocytes. The interpretation of fate-mapping studies depends upon multiple assumptions: (i) that expression of cre recombinase has no effect on monocyte-macrophage homeostasis, (ii) that tamoxifen is a neutral agonist, (iii) that life in an SPF animal facility reflects the normal life course of a mouse, and (iv) that the C57Bl/6J inbred mouse is a generalizable model and the biology of the MPS is unaffected by mouse genetic background or species."

onlinelibrary.wiley.com/doi/10

A great week at the soon to be extinct Gulbenkian Science Institute/IGC teaching MD PhD students of the EMERALD program.

emerald-mdphd.eu

Civilization dies when the only answer to "why can he do that?" is "because you can't stop him."

On this day in 1991: Michael Heidelberger died aged 103, key pioneer of immunochemistry #ThisDayInBiotech

@futurebird That sounds like it would get gravy all over my 6 inch lapels and permanently stain my satin bell bottoms

'Nos últimos 17 anos, Portugal enviou 309,6 milhões de euros para Universidade Carnegie Mellon, o Instituto de Tecnologia do Massachusetts (MIT) e a Universidade do Texas em Austin​, contou António Sousa Pereira, explicando que as transferências se inserem numa parceria lançada entre 2006 e 2007, através da Fundação para a Ciência e a Tecnologia (FCT).'

publico.pt/2023/06/23/ciencia/

'The clinic is not just a place where Gaustine treats patients; it is also the perfect conceit for Gospodinov’s narrator to explore the 20th century in Europe through the vanishing points of traumatised or broken individuals. It’s as if Oliver Sacks and WG Sebald had collaborated on a Europe-wide chain of treatment centres.'

theguardian.com/books/2022/may

Communicating science through art: engaging conversation at the @Ecsite conference last week, with ERC grantee @kostas_nikolop of @unibirmingham.
Read more about his #sciart #scicomm activities 👉 erc.europa.eu/projects-figures t.co/9vojhS836f

🐦🔗: n.respublicae.eu/ERC_Research/

This is how the #EuroVelo network looks like in 2023 🚲⁠

Go far away or simply discover your region: the choice is yours!

This summer, pick your favourite route and explore our continent using cleaner, cheaper and healthier forms of transport.

Gears ready? Get a #map with information and tips about the 17 EuroVelo routes

🔗 eurovelo.com/support-us⁠

#EUGreenDeal #Cycling

'To address this critical knowledge gap, we conducted a comprehensive cross-species analysis of transcriptomic data from over 6000 blood samples from macaques and humans infected with one of 31 viruses, including , , , , and .'

biorxiv.org/content/10.1101/20

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