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@cyrilpedia honestly, speaking from a UK perspective, the idea that (obviously non-generic) drugs are marketed straight to patients utterly bemusing!

Is the idea genuinely that the half-informed patient sees it and then goes to their doctor asking about/for it?!

I guest-posted on @DNA 's Samuraipunk substack "Accidental Samurai: How I became, despite my best intentions, a cyber-biopunk novelist.

samuraipunk.substack.com/p/acc

@cyrilpedia interesting. You can see how a signal came out in that population. My hunch is that it's time & dose dependent, but that doesn't massively help in autoimmune conditions in which treatment is long, spanning into years potentially.

Thank you.

@gpollara I agree completely - this is a lifelong treatment. I'm in NY right now and the advertisements for ruxolitinib are everywhere.

The most recent Podcast I produced for EMBO was with Pavel Tomancak (and EMBO's Thomas Lemberger). One detail that might get missed in a wide ranging conversation about science, policy, science fiction and more was Pavel's passing comment on how one important consideration in his decision to return to Europe after a very productive time at UC Berkeley were serious reservations about the US healthcare system.

embo.org/podcasts/who-reviews-

@gpollara I don't think we have enough data on that - the group that generated the warning (in another trial set) was oder and had a range of pre-existing conditions.

there’s a full-on conservative war against librarians.

not hard to imagine why they hate the people helping children expand their minds and imagine a better world.

Well, I'm on the #job market. I hold a master in Computational Social Science and am currently based in #Madrid, #Spain.

💻 I am proficient in #R and #SQL, and capable to work with #Python and #QGIS.

🗣️Spanish and English

If anyone has information on any jobs related to Data Analysis, Data Science, Research, etc. I would be very grateful if you could let me know!

#jobsearch

@josemanuel Salaries in Portugal are very low, and housing costs in the cities are not very different from any major European capital.

My new Clinical Pipeline column is out in Nature Medicine.
It's on JAK inhibitors for alopecia - and at the black box safety warning the FDA attached to this entire class of drugs.

nature.com/articles/d41591-023

@josemanuel It's considered a reasonable wage by Portuguese standards, which are abysmal.

"Maps 1 & 4 The Conan Map (Brest, France, 16th Century)

This Renaissance print is a copy of a vellum drawn circa 1156 at the behest of Conan IV (“the Black”), Duke of Brittany, during a dynastic dispute with King Henry II of England, who was also Count of neighboring Anjou. As shown in the inset, the image’s purpose is solely to assert power and legitimacy. The multiple lines shown in the inset (the only remaining panel of a set of three) proclaim the conquest and rule of the corresponding regions by the Duke and his kinsmen in the House of Penthièvre."

#ArtGallery

madalenaparreira.com/SPAM

In Paper 4 of a new @bmj_latest Series, @healthlawadamh @madhupai @drejoanneliu @roojinhabibi @srinmurthy99 examine the tensions between domestic & international priorities in access to #covid vaccines, arguing Canada failed to follow through on pledges
bmj.com/content/382/bmj-2023-0

'In this Comment, I use examples from clinical trials presented at the 2023 ASCO annual meeting to highlight why ‘allowing’ crossover in randomized trials testing cancer drugs is problematic, and propose that crossovers should either be mandated or prohibited depending on the context.'

nature.com/articles/s41571-023

Upon their return, Black veterans encountered violence back in America. In 1946, an appalling incident occurred in Georgia, where a mob shot and killed 2 Black men and their wives, with no one brought to trial for the crime. In South Carolina, police subjected Army Sergeant Isaac Woodard to a brutal beating with night sticks after pulling him from a bus, leaving him permanently blind.

23/

#BlackMastodon #Histodons #History #BlackMastodon #BlackHistory #Military #StillWeRise #Truman #Missouri

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#IDMastodon #Viralimmunology #CaseReport @Cureus A Case of #postCOVID19 Rhino-Cerebral #mucormycosis in an Immunocompromised Patient . It is theorized that the infection caused by severe acute #SarsCoV2 might impact the cluster of differentiation CD4+ & cytotoxic T cells (CD8+), which play a significant role in the pathological progression of #COVID19.

If you're considering grad school in Portugal, don't forget to inquire about housing:

'Like so many people in Portugal, where rental prices make a mockery of the low salaries, Custódio lives through a monthly agony when it comes to covering the costs of her flat. Despite a good job in human resources, she earns €930 (£795) a month after tax – of which €700 goes on rent.'

theguardian.com/world/2023/jul

#IDMastodon #CovidIsNotOver @WHO 🧵 twitter.com/mvankerkhove/statu by @mvankerkhove “We will continue to see waves of #COVID19, the virus is still evolving and will continue to change with such intense circulation.”
We do not yet have a predictable pattern of evolution, we don’t have seasonality, we are at risk for more severe variants…
who.int/activities/tracking-SA

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