Thiago Carvalho @cyrilpedia@social.cleverlibre.org
I've worked on all of science, from B cells to T cells.
https://fellowsherpa.com
Joined Nov 2022
@Retropz Thanks for sharing that.
Thiago Carvalho
boosted
@cyrilpedia 8th World Conference on #ResearchIntegrity produced a statement to try to address this issue - https://www.wcrif.org/guidance/cape-town-statement
Thiago Carvalho
boosted
When will the British follow ?
Their museums are full of plundered objects from slave nations and the RF even wears plundered jewels
@humanrightswatch @humanrights @PIL@mastodon.lawprofs.org @pil@a.gup.pe
"Most scientific-journal articles come from wealthy countries in the global north. Often, well-funded researchers initiate short-term projects in southern countries — which are typically poorer and often have a history of colonial occupation — frequently without seeking substantive local input or expertise. Dubbed parachute or helicopter research, this is a long-standing tradition steeped in colonialism, say those campaigning for change."
@dmacphee Portugal is a disgrace: I cant even go to Madrid by train anymore but all the government discusses is how to build more airports.
Thiago Carvalho
boosted
LAG3 ICIs
"With this approval, LAG-3 became the third checkpoint inhibitor to show efficacy when targeted in the clinic, The response profile of Opdualag is comparable to the ipilimumab/nivolumab (anti-CTLA4/anti-PD-1) combination (47.7% versus 49% 12-month PFS), although 59% of patients had severe adverse events with ipilimumab/nivolumab compared with only 18.9% with Opdualag"
Thiago Carvalho
boosted
'We compare collective performance in structured information–sharing networks to collective performance in independent control groups, and find that networks significantly reduce clinical errors, and improve treatment recommendations, as compared to control groups of independent clinicians engaged in isolated reflection.'
Thiago Carvalho
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"Heat damage to underground cables"? WTF!!!
Italian city ‘brought to its knees’ by power cuts caused by #heatwave
by Jasper King, Tuesday 25 Jul 2023
"Hundreds of thousands people are facing blackouts and are without electricity in #Sicily during a scorching heatwave.
"Temperatures on the Italian island have soared to 47.6°C, with warnings Catania has been ‘brought to its knees’ by the power cuts.
"It is believed the power cuts have been caused by heat damage to underground cables.
"Between 200,000 to 300,000 people have been impacted by water pumps stopping but the issue was resolved on Monday morning."
https://metro.co.uk/2023/07/25/huge-blackouts-on-sicily-impact-half-a-million-people-19186076/
'July is a hard month for a lot of us here in New Mexico, where thousands of people’s lives were upended by the test of the world’s first nuclear bomb. The events of July 16, 1945, weigh heavily on us. And why wouldn’t they? They changed everything. The people of New Mexico were the first human test subjects of the world’s most powerful weapon.'
https://www.nytimes.com/2023/07/30/opinion/international-world/oppenheimer-nuclear-bomb-cancer.html
Thiago Carvalho
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Researchers found both compositional & functional gut #microbiome differences in people with various types of arthritis and I like their caution in concluding these are probably a RESPONSE to system-wide inflammation, rather than the cause of it.
https://www.science.org/doi/10.1126/scitranslmed.abn4722
Thiago Carvalho
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And another paper likely to get the proteomics crowd hitting their keyboards in a frenzy :-)
Proteome-wide copy-number estimation from transcriptomics | https://www.biorxiv.org/content/10.1101/2023.07.10.548432v1.full.pdf+html #proteomics
Thiago Carvalho
boosted
If you're considering grad school in Portugal, don't forget to inquire about housing:
'Like so many people in Portugal, where rental prices make a mockery of the low salaries, Custódio lives through a monthly agony when it comes to covering the costs of her flat. Despite a good job in human resources, she earns €930 (£795) a month after tax – of which €700 goes on rent.'
Thiago Carvalho
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My new Clinical Pipeline column is out in Nature Medicine.
It's on JAK inhibitors for alopecia - and at the black box safety warning the FDA attached to this entire class of drugs.
#Immunology #drugdiscovery #drugdevelopment #alopecia
Thiago Carvalho
boosted
I don't think everyone realizes how much #neuroscience #opendata is really downloaded and reused...
e.g. our dataset of responses to visual stimuli has 18,000 downloads; wholebrain #zebrafish neural activity from the Ahrens lab has 7,000 downloads; Nick Steinmetz's eight-probe Neuropixels data has 6,500 downloads. and there are many commonly used neuro datasets on websites that don't count downloads that must have thousands too!
post your data and they will come :) #openscience
Thiago Carvalho
boosted
One day we're going to have to stop trusting papers from people who have demonstrated their untrustworthiness.
Thiago Carvalho
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Senior Bioinformatician
MRC London Institute of Medical Sciences
We are seeking a skilled and motivated Senior Bioinformatician with significant experience in genomics and transcriptomics to join the Facility.
See the full job description on jobRxiv: https://jobrxiv.org/job/mrc-london-institute-of-medical-sciences-27778-senior-bioinformatician-2/?feed_id=52713
#ScienceJobs #hir...
https://jobrxiv.org/job/mrc-london-institute-of-medical-sciences-27778-senior-bioinformatician-2/?feed_id=52713
Thiago Carvalho
boosted
@gpollara I couldn't agree with you more.
I've worked on all of science, from B cells to T cells.
https://fellowsherpa.com
Joined Nov 2022
