Thiago Carvalho @cyrilpedia@social.cleverlibre.org

Postdoctoral Research Fellow: Alternative Splicing in Pancreatic Cancer Metastasis

Moffitt Cancer Center

See the full job description on jobRxiv: https://jobrxiv.org/job/postdoctoral-research-fellow-alternative-splicing-in-pancreatic-cancer-metastasis/?feed_id=55734

#ScienceJobs #hiring #research
Tampa #UnitedStatesUS #PostdoctoralFellow #Researcher
https://jobrxiv.org/job/postdoctoral-research-fellow-alternative-splicing-in-pancreatic-cancer-metastasis/?feed_id=55734

#MEDMASTODON

FDA’s ‘Standing’ problem: Why the mifepristone court case could lead to more challenges to product approvals

The moving story of Carol Jennings, APP and Alzheimer's

In all my years as a brain researcher, I didn't think to sit down and learn the stories of individuals afflicted with brain dysfunction until I sat down to write a book. Learning their stories has been one of the most impactful parts of this experience.

Among them: Carol Jennings. In an era in which the causes of Alzheimer's were not thought to be genetic, Carol's father and four of his siblings were all diagnosed with the disease at the ages 54-58. She started writing letters to Alzheimer's researchers wondering if her family could contribute to some type of study. One of those letters was written to John Hardy and it set off a chain of events that changed the course of Alzheimer's research for the next 30 years.

"Dear Sir, I was very interested to read of your research in the Alzheimer’s Disease Society News and think my family could be of use ... please contact me at the above address if you think we could be of help." April, 1986.

That letter led to the discovery of a single point mutation in the gene APP that leads to the protein beta-amyloid. It was a key step toward Hardy and others launching the amyloid cascade hypothesis, which in turn led to the new Alzheimer's drugs. (While their effectiveness thus far is questionable, they are a necessary step).

Carol spent the next 30 years as a patient advocate. She refused to be tested for the gene herself absent a cure. Tragically, she was diagnosed with the disease in 2012.

Here's more about Carol and her devoted husband and caregiver, Stewart.
https://www.alzheimers.org.uk/blog/honouring-couple-dementia-their-contributions-research
(Watch the movie. Have tissues ready).

Take the ability to block away, and Twitter immediately becomes utterly unusable for anyone who doesn’t revel in being overwhelmed by an avalanche of racist, misogynistic, bigoted filth - and that’s intentional, of course. An incitement of abuse.

https://variety.com/2023/digital/news/elon-musk-x-twitter-block-feature-delete-1235699759/

Biological Imaging Development CoLab (BIDC) Director UCSF

UCSF

Dream of spearheading innovative microscopy research? Lead our Biological Imaging Development CoLab team to new heights in scientific discovery.

See the full job description on jobRxiv: https://jobrxiv.org/job/ucsf-27778-biological-imaging-development-colab-bidc-director-ucsf/?feed_id=55725

#ScienceJobs #hiring #research...
https://jobrxiv.org/job/ucsf-27778-biological-imaging-development-colab-bidc-director-ucsf/?feed_id=55725

During WWI, Marie Curie created a vehicle that contained a hospital bed, a generator, an X-ray machine and photographic darkroom equipment. These “petite Curies" (below) could be driven right up to the Front. Curie also helped train 150 women as radiology technicians.

#histmed #histsci #WWI #warhistory #war #medhist #science #womeninstem #womenshistory #histodon #histodons #twittermigration #twitterexodus

@gwensnyder

To those hopeful that #BlueSky is the answer, Jack Dorsey in full agreement with Musk's plan to remove blocking is crucial to know.

Jumping from one billionaire's playground to another won't fix any problems – especially when the two billionaires are good chums.

Scorching ‘new normal’ as world buckles under extreme heat: WMO
#AureFreePress #News #weather #GlobalWarming #climatechange #UN

https://news.un.org/en/story/2023/08/1139867

'Our aim was to answer two questions: (1) Is COVID-19 vaccine hesitancy, intention, or uptake associated with HPV or hepatitis B (HBV) vaccine hesitancy, intention, or uptake? and (2) Is exposure to COVID-19 vaccine misinformation on social media associated with HPV or HBV vaccine hesitancy, intention, or uptake?'

https://elifesciences.org/articles/85743

"Another key parameter in CAR T cell infusion products is the ratio of CD4:CD8 T cell subsets. Yet, it is unclear whether CD4+ and CD8+ CAR T cells have the same propensity to induce CRS. This is particularly relevant since CD4:CD8 ratios can vary extensively in distinct infusion products."

#Immunology #immunotherapy #CARTCells

https://www.cell.com/cell-reports-medicine/fulltext/S2666-3791(23)00314-2

ACT 💪 Kämpfe mit uns für soziale & ökologische Gerechtigkeit und unterstütze unsere Petition für ein Verbot von Privatjets!
👉 https://greenpeace.org/international/act/ban-private-jets/ 3/3

#BanPrivateJets #TaxTheRich #MakePollutersPay #Klimawahl #Bayern

“The #ProudBoys literally made the attack on the Capitol into a coin of their terrorist group.”

Marcy Wheeler (@emptywheel) on the challenges facing prosecutors when defendants acting like terrorists are White rather than Islamic.

Also, Proud Boy Christopher Worrel skipped bail on Friday.

https://www.emptywheel.net/2023/08/18/the-challenge-of-treating-the-proud-boy-leaders-treated-as-terrorists/

#January6th

Cancel the meeting

Are the managers in some way guilty of homicide?

#Letby

https://www.theguardian.com/uk-news/2023/aug/19/doctors-were-forced-to-apologise-for-raising-alarm-over-lucy-letby-and-baby-deaths