Thiago Carvalho @cyrilpedia@social.cleverlibre.org
I've worked on all of science, from B cells to T cells.
https://fellowsherpa.com
Joined Nov 2022
"In a mouse model, neutralizing IL-10 signaling through antibodies, genetically ablating IL-10R1 in sensory neurons, or depleting monocytes with clodronate all impaired the resolution of pain hypersensitivity in both sexes."
#Preprint #Immunology #Neuroimmunology
Thiago Carvalho
boosted
"Amanda Sierra never intended to organize a weekend conference. “It is extremely disrespectful to start a conference over the weekend; it is almost insulting for the intrusion on family time and private life,” says the cell biologist at the Achucarro Basque Center for Neuroscience in Leioa, Spain. At past conferences, Sierra would make a political statement of leaving early or asking organizers to change the date of her talk to avoid having to spend weekends away from her child"
Thiago Carvalho
boosted
MICa/b-dependent activation of natural killer cells by CD64+ inflammatory type 2 dendritic cells contributes to #autoimmunity
Pathology of primary Sjögren's syndrome is known to involve #interferons, but Enrique Martin-Gayo et al @UAM_Medicina show additional roles also for #innateimmune cells like natural killer and #dendritic cells
Thiago Carvalho
boosted
New (targetable) way for #pancreatic cancer to turn off the #Hippo pathway and activated #YAP: #PRMT5-mediated arginine #methylation suppressing dimerization, autophosphorylation, and activation of the Hipp initiator kinase #MST2
https://www.embopress.org/doi/full/10.15252/embj.2023114558
I hope infectious disease got the message too:
“I’m gonna say to NIH scientists, God bless you all,” Kennedy said. “Thank you for public service. We’re going to give infectious disease a break for about eight years.”
Thiago Carvalho
boosted
"I always think about climate justice as multitasking. We live in a time of multiple overlapping crises: we have a health emergency; we have a housing emergency; we have an inequality emergency; we have a racial injustice emergency; and we have a climate emergency, so we’re not going to get anywhere if we try to address them one at a time. We need responses that are truly intersectional. So how about as we decarbonise and create a less polluted world, we also build a much fairer society on multiple fronts?"
Sitting in on Luis Graça's lab retreat in paradise with no wifi.
Our regular programming will resume soon.
"The report shows that Japan ranks third globally in the total number of researchers, following China and the United States. However, this workforce is not producing the same level of high-impact research as it was two decades ago. Japan’s global share of research papers in the top 10% of most-cited articles has slipped from 6% to 2%, intensifying concerns in Japan about its dwindling international standing."
Thiago Carvalho
boosted
Investigating the role of mitochondrial membrane potential in paternal inheritance of mitochondria https://www.biorxiv.org/content/10.1101/2023.10.30.564200v1?med=mas
"We’ll tell you “twenty minutes” as I hold in my laughter and high-five our delivery guy. If it does arrive, you’ll eat it, unconvincingly telling your loved ones that it tastes just like the pizza at Bleecker Street pizzeria in the city. Only you’ll know it tastes more like Bleecker Street, the street in the city."
Thiago Carvalho
boosted
In her ‘Latin American Microscopists’ interview series, Mariana De Niz chats with Manuela Aguirre, a PhD student at Institut Pasteur. They discuss Manuela's career (moving from Colombia to Germany and France), her love of parasitology and her hopes for the future.
https://focalplane.biologists.com/2023/10/31/an-interview-with-manuela-aguirre-botero/
Thiago Carvalho
boosted
The chain of events was: Neil Gaiman said I was not the problem. @madparreira commemorated it in a plate.
#ceramics #pottery #handmade #artgallery #stoneware #artstagram
"Here, we review insights from ecology and evolution and their application throughout abiogenesis. In particular, we discuss how ecological and evolutionary constraints shape the evolution of biological innovation"
https://academic.oup.com/evolut/advance-article/doi/10.1093/evolut/qpad195/7334978?searchresult=1
Thiago Carvalho
boosted
Antibodies to treat Pseudomonas infection?
Well, maybe....
#immunology #microbiology #antibodies #Pseudomonas
https://www.cell.com/cell/fulltext/S0092-8674(23)01084-X
"Amanda Sierra never intended to organize a weekend conference. “It is extremely disrespectful to start a conference over the weekend; it is almost insulting for the intrusion on family time and private life,” says the cell biologist at the Achucarro Basque Center for Neuroscience in Leioa, Spain. At past conferences, Sierra would make a political statement of leaving early or asking organizers to change the date of her talk to avoid having to spend weekends away from her child"
Thiago Carvalho
boosted
"He was doing physical therapy, spending time with family members, and playing cards with his wife, according to the university. But in the days leading up to his death, his heart began to show signs of organ rejection; in other words, his immune system recognized the pig heart as foreign and attacked it. "
https://www.wired.com/story/pig-heart-transplant-lawrence-faucette-death/
Thiago Carvalho
boosted
What to know about the bleeding virus detected in French ticks
6–7 minutes
French authorities said that Crimean-Congo haemorrhagic fever (CCHF) was detected in ticks in southern France this month. Climate change favours their further spread, experts say
#MassExtinction #pollution #ecology #environment #climate #France
Thiago Carvalho
boosted
"Cephalopod cognition also considerably widens the evolutionary gamut of intelligence, showing that it can evolve without a vertebrate Bauplan — without an internal skeleton or skull or vertebrate brain architecture. An intelligent animal so radically different from us somehow makes our place in evolution seem a little less special. To us, oh so sapient, humans, cephalopods are a distant mirror, one that may reflect — and deflect — some explanations for the evolution of intelligence generally."
https://www.cell.com/current-biology/fulltext/S0960-9822(23)01302-7
The chain of events was: Neil Gaiman said I was not the problem. @madparreira commemorated it in a plate.
#ceramics #pottery #handmade #artgallery #stoneware #artstagram
I've worked on all of science, from B cells to T cells.
https://fellowsherpa.com
Joined Nov 2022
