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In Portugal, as everywhere else in the world, if men could not vote, there would be no far right problem.

"(...) o Ch*ga é claramente mais masculino (mais oito pontos do que entre elas)."

dn.pt/politica/ps-alarga-dista

Labour peers urged to back fatal motion and protect worker's right to strike

"It's unthinkable, it's unworkable, it's almost certainly illegal and even worse the government is willing to outright lie to the public to get away with it"

thelondoneconomic.com/politics

PFKFB3 is a critical regulator of neutrophil metabolism and function in rheumatoid arthritis medrxiv.org/content/10.1101/20

PROTEOME-SCALE RECOMBINANT STANDARDS AND A ROBUST HIGH-SPEED SEARCH ENGINE TO ADVANCE CROSS-LINKING MS-BASED INTERACTOMICS biorxiv.org/content/10.1101/20

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#proteomics #prot-preprint

Last month NHS England awarded a £330m contract to the US company Palantir for the procurement of a data platform for the NHS.

@jessrmorley and @drjzhn look at why the decision has caused controversy
bmj.com/content/383/bmj.p2776?

In Portugal, as everywhere else in the world, if men could not vote, there would be no far right problem.

"(...) o Ch*ga é claramente mais masculino (mais oito pontos do que entre elas)."

dn.pt/politica/ps-alarga-dista

The COP 28 President is talking utter BS.
“Al Jaber is asking for a 1.5C roadmap – anyone who cares can find that in the International Energy Agency’s latest net zero emissions scenario, which says there cannot be any new fossil fuel development. The science is absolutely clear [and] that absolutely means a phase-out by mid-century, which will enhance the lives of all of humanity.”
#ClimateChange #Science #Environment #Canada

theguardian.com/environment/20

AlphaFold & PDL1

"Here, we test a protein design pipeline that uses iterative rounds of deep learning (DL)-based structure prediction (AlphaFold2) and sequence optimization (ProteinMPNN) to design autoinhibitory domains (AiDs) for a PD-L1 antagonist."

pnas.org/doi/10.1073/pnas.2307

Record drought could keep Amazon dry through 2026
"From killing hundreds of endangered river dolphins -
to threatening the livelihoods of millions of people.

This is the impact of the Amazon #rainforest's historic #drought.

Its sapped the #AmazonRiver and four of its biggest tributaries to their lowest level in at least half a century.

And the worst may be yet to come.

Experts are predicting an even more intense drought next year - due to extreme ocean temperatures worsened by global warming." #climate #Brazil
news.yahoo.com/record-drought-

For fucking fuck’s sake, whose genius idea was it to put the wolf in charge of the sheep’s emergency anti-predator conference?? Our civilisation is completely doomed. Sorry kids.

"We hypothesized that elevated Gαq stimulation within the syncytiotrophoblast layer contributes to the pathogenesis of through disruption of normal redox balance and thus the induction of syncytiotrophoblast stress."

science.org/doi/10.1126/sciadv

"Here, we summarize the latest insights into cellular uptake mechanisms and pathways in DCs. We highlight the approaches to study endocytosis, the impact of endocytosis routes on T cell response, and discuss the link between how DCs internalize therapeutic antibodies and the potential mechanisms that could give rise to immunogenicity"

onlinelibrary.wiley.com/doi/ab

Buster Keaton's "The General" at one of Lisbon's most special spots, a Cinemateca Portuguesa. Bonus: accompanied by a live pianist.

cinemateca.pt/Entrada.aspx

“This release . . . is the culmination of 20 years of work and it’s the largest ever release of whole genome sequences in history,” said Cheryl Moore, chief research programmes officer at the Wellcome Trust. “Scientific data that is openly shared allows everyone to contribute groundbreaking discoveries.”

ft.com/content/adb936b9-45b0-4

🇨🇵 🌊 Open position
Director of the Biological Marine Station in #Roscoff, France
🤓 🖥️ 🧪 🦠 🐚 🔬 🧬 📝
deadline: 29 February 2024
@roscoff @cnrs

"The book wasn’t published for two years, not before perestroika and Gorbachev. “After reading your book no one will fight,” the censor lectured me. “Your war is terrifying. Why don’t you have any heroes?” I wasn’t looking for heroes. I was writing history through the stories of its unnoticed witnesses and participants. They had never been asked anything."
- Svetlana Alexievich

nobelprize.org/prizes/literatu

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