Thiago Carvalho @cyrilpedia@social.cleverlibre.org
I've worked on all of science, from B cells to T cells.
https://fellowsherpa.com
Joined Nov 2022
Submission Deadline: 01/11/24 02:00 PM WET
"With $1,000,000 in prizes, the NIH is seeking your ideas that will help demonstrate new ways of conducting basic research, uncovering disease mechanisms, and translating knowledge into products and eventually into practice."
"By the end of 2021, more than a fifth of job transitions from large companies in Japan were people leaving to join start-ups, according to the Japan Venture Capital Association, compared with 8 per cent in 2018. That proportion has continued to push towards 25 per cent, according to JVCA members."
https://www.ft.com/content/562f1c34-c1c3-400f-8d93-f6f5fa0bcce9
Thiago Carvalho
boosted
"We argue that only by considering placentas as 3D biological structures, integrated across scales, can the evolutionary questions behind their enormous structural diversity be quantitatively determined."
https://academic.oup.com/evolut/advance-article/doi/10.1093/evolut/qpad209/7425018?searchresult=1
Thiago Carvalho
boosted
"The whole game of intellectual ownership here has been so stylised that it is hard to discern the purpose, even if we all recognise the rules. For example, when the second paragraph of this column lifted 13 words verbatim from the King James Bible, was that plagiarism? Obviously not. But only because everyone knows that I was quoting from the Bible. If the copying is blatant enough, it is no longer plagiarism but homage."
Thiago Carvalho
boosted
It seems Joey may not be the worst Buttafuoco
Thiago Carvalho
boosted
"In fact, research indicates that, in labs where postdocs are more engaged, PhD students can be 4 times as likely to have positive skill development; mentoring by principal investigators had no discernible statistical effect on the same variable"
https://journals.plos.org/plosbiology/article?id=10.1371/journal.pbio.3002349
Thiago Carvalho
boosted
CDK4/6 inhibitor-mediated cell overgrowth triggers osmotic and replication stress to promote senescence https://www.cell.com/molecular-cell/fulltext/S1097-2765(23)00853-5?rss=yes&utm_source=dlvr.it&utm_medium=mastodon
"After Mr. Escobar was killed in a rooftop shootout with security forces in Medellín in 1993, his hippos fended for themselves. They waddled into an artificial pond and reproduced, drawing affection and ire as their numbers multiplied."
https://www.nytimes.com/2023/11/18/world/americas/colombia-hippos-pablo-escobar.html
"That conflict between fast growth and A.I. safety came into focus on Friday afternoon, when Mr. Altman was pushed out of his job by four of OpenAI’s six board members, led by Mr. Sutskever. The move shocked OpenAI employees and the rest of the tech industry, including Microsoft, which has invested $13 billion in the company. Some industry insiders were saying the split was as significant as when Steve Jobs was forced out of Apple in 1985."
https://www.nytimes.com/2023/11/18/technology/open-ai-sam-altman-what-happened.html
Thiago Carvalho
boosted
Fibrillinopathies.
"A number of mouse models have been created in an attempt to replicate the human phenotype, although all have limitations. There are also natural bovine models and engineered models in pig and rabbit."
Thiago Carvalho
boosted
"Given that up to 20% of clinical trial costs is related to the manual transfer and verification of data from the electronic medical record to a data capture system, as well as the site monitoring of such data, all of which are readily automated tasks, the application of AI to clinical trials could be revolutionary and is likely necessary."
Thiago Carvalho
boosted
"The media watchdog Media Matters said earlier this week that it found corporate advertisements by IBM, Apple, Oracle and Comcast’s Xfinity were being placed alongside antisemitic content, including that praising Adolf Hitler and the Nazis."
Thiago Carvalho
boosted
Fact-Check: More Bacteria than Human Cells in the Body?
https://www.truthorfiction.com/fact-check-more-bacteria-than-human-cells-in-the-body/
Thiago Carvalho
boosted
New post looking ahead at what's in store for the NHS this winter.
TLDR it's not pretty but I suspect we'll about last year's disaster but*only* because we avoid a triple peak of covid, RSV and flu in December.
That 'select' has been the problem for the last decade
"These results suggest that programmed cell death protein 1 blockade may benefit a select group of patients with brain metastases, and support further studies to identify biomarkers and mechanisms of resistance."
#Immunology #Immunotherapy
Thiago Carvalho
boosted
'Pocone, Brazil
A group of caimans sit on the banks of the almost dried-up Bento Gomes river in the Pantanal wetlands.
Photograph: André Penner/AP'
Thiago Carvalho
boosted
ICYMI on Wednesday, "Genetic Dissection of the TLR Paradox in SLE", a very interesting 'Global Immunotalks' seminar by Mark Shlomchik.
#Immunology
Joan Jara (1927-2023)
"No dia em que o Chile sofreu um golpe de Estado perpetrado por Augusto Pinochet, com o apoio dos Estados Unidos, a 11 de Setembro de 1973, Joan e Victor Jara ouviram em casa, pela rádio, a última comunicação do presidente Salvador Allende, que morreria pouco depois no Palácio de La Moneda, na capital do país. No final da comunicação, ele saiu para se juntar aos protestos numa universidade e esperar o desenrolar dos acontecimentos. “Não olhei para o ver partir. Não parecia importante. Disse adeus de forma habitual. Foi a última vez que o vi”, contou, décadas depois, Joan Jara ao britânico The Guardian. Uma luta diferente começava ali para ela."
Thiago Carvalho
boosted
Time to delete our Research Gate accounts. #PredatoryPublishing sucks.
Time traveling to 1997, the Post covering the arrival of effective combination therapy for HIV. I like particularly like this bit:
'But David Ho didn't invent protease inhibitors. He is just one of a group of major international researchers, dubbed the "new guard" by the science press, who played a role in exploring their possibilities. And he is the first to acknowledge that the drug companies themselves -- usually the least likely source of groundbreaking science -- did most of the heavy lifting. "The feeling in the labs," recalls Merck CFO Judy Lewent, "was that this was Nobel laureate caliber work. And, in the drug industry, we don't get to think about that all too often."'
I've worked on all of science, from B cells to T cells.
https://fellowsherpa.com
Joined Nov 2022
