#Microbial #predators form a new supergroup of #eukaryotes | Nature
😮😮
"While the COVID-19 pandemic exposed inherent systemic limitations of the clinical trial landscape, it also spurred some positive changes, including new trial designs and a shift toward a more patient-centric and intuitive evidence-generation system. In this Perspective, I share my heuristic vision of the future of clinical trials and evidence-based medicine."
Into the "submarine fairyland" – how the scientific artist Else Bostelmann invited the human imagination into the wonder-world of the deep sea at a time when it was more mysterious than the Moon https://www.themarginalian.org/2022/01/14/else-bostelmann/
'At the back of the kitchen, a robot churns out tiny blocks of rice at the rate of about 3,600 an hour. “It’s impossible for a chef to do it that quickly,” said Yurika Murai, from Sushiro’s public relations department. Each block is identical and served up, as tradition demands, at skin temperature.'
@NicoleCRust @gregeganSF
In Larry Niven's "A world out of time" the hero learns new stuff by injecting RNA to help consolidate the memory.
The field is not there yet, but maybe in a couple of decades of studying RNA transport within and between dendrites, axons, neuron-glia etc... we can make it to work.
"We utilise ecDNA amplicon structures to determine precise ecDNA copy numbers and reveal extensive intercellular ecDNA copy number heterogeneity. We further provide direct evidence for the effects of this heterogeneity on gene expression of cargo genes, including MYCN and its downstream targets, and the overall transcriptional state of neuroblastoma cells."
Such a cool idea, a CART cell gel to clean surgical borders (work done in mouse models).
"To develop a therapy for incompletely resected adenocarcinoma, we have established tumor models by incomplete surgical excision of subcutaneous tumors and the intraoperative application of mesothelin-specific CAR T cells in a fibrin glue–based carrier (fibrin gel) on the residual tumor and wound surface without the need for intratumoral injection."
I'm new to Mastodon and looking for #microbiologists to follow. #microbiology #science
I just migrated to this server, still figuring it all out!
#Coronavirusupdates #China 1/22/23
As of Jan 19, 472,000 #COVID19 hospitalizations (Severe disease: 51,700).
Weekly #COVID related deaths at hospitals: 12,658 (681 deaths with respiratory failure)
Figures do not include those who died at home.
http://www.chinadaily.com.cn/a/202301/22/WS63cced87a31057c47ebab0c1.html
That's art from 1670. You see a trompe-l'œil painting by Cornelius Norbertus Gysbrechts with the title "The Reverse of a Framed Painting". Enjoy, #histodons. #history
Access the painting: https://open.smk.dk/artwork/image/KMS1989
I've been thinking about how we might encourage more new Big Ideas in science (especially brain research).
There's a lot to unpack there, but one thing that works for some scientists: reading speculative fiction / #scifi. Science excels at its rigor but it can also stifle creativity. Speculative fiction is one way to open that gate back up again.
Here are a few of my favorite #specfic stories about the mind and brain and the big ideas that they are written around.
Ted Chiang, The Truth of Fact, the Truth of Feeling”. Big idea: our personal (and cultural) identities rely on the fallibility of memory.
@gregeganSF, "Axiomatic". Big Idea: we should be wary of perturbing brains to relieve angst.
Ken Liu, "The Cleaners", Big idea: Our attachment to memory defines us.
Jennifer Egan, "The Candy House". Big idea: Sharing our memories has both beneficial and negative consequences.
What are your favorite #specfic stories and what Big Ideas are they attached to?
Shrines in snowy mountains #ukiyoe #utagawahiroshige https://www.wikiart.org/en/hiroshige/shrines-in-snowy-mountains
#IDMastodon #ObstetricMedicine #ClinicalIvestigation Boosting maternal and neonatal anti–#SARSCoV2 humoral immunity using a third mRNA vaccine dose
https://insight.jci.org/articles/view/158646
22 January 1945 | During the evacuation march of prisoners from Auschwitz III-Monowitz, near Gliwice, SS guards shot Victor Perez, a Tunisian Jewish boxer, the World Flyweight Champion in 1931 & 1932. He was deported to Auschwitz in October 1943.
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Listen to our podcast about sport and sportspeople at Auschwitz: https://anchor.fm/auschwitz-memorial/episodes/On-Auschwitz-11-Sport-and-sportspeople-in-Auschwitz-e19hmok
#Auschwitz #Birkenau #Holocaust #Shoah #Jews #history #histodons #Nazis #Germany #NeverForget #ww2 #boxing #sports #podcast #Tunisia #otd #facts #boxer
I've worked on all of science, from B cells to T cells.
https://fellowsherpa.com