Thiago Carvalho @cyrilpedia@social.cleverlibre.org

"But before you write us off as insensitive or bad writers, let me tell you that open notes are challenging for doctors, too. Maybe explaining why will indeed improve your health, relationship with your doctor, and my profession."

cc @BLMG

https://nautil.us/why-reading-your-doctors-notes-can-be-painful-257796/?_sp=7cd16a6c-2b45-4fc9-bfdd-6b8f45873a33.1674517534486

"Human agriculture has shaped the planet for millennia, but leaf-cutters began cultivating food at scale millions of years earlier. The ants are responsible for a quarter of all plant consumption in their ecosystems; worker ants might travel two hundred yards to collect leaf clippings, cutting tons of plant material a year."

https://www.newyorker.com/culture/persons-of-interest/the-artist-who-collaborates-with-ants

"This study examined the effects of lung infection causing systemic and neuroinflammation as a potential mechanism contributing to blood-brain barrier (BBB) leakage and behavioral impairment."

#Preprint #Neuroimmunology #BloodBrainBarrier #Immunology #Infection #InfectiousDisease

https://www.biorxiv.org/content/10.1101/2023.01.23.524949v1

"Meanwhile, our share of the global pharmaceutical R&D market is declining. UK-based academics are now barred from the Horizon EU research programme, preventing them from participating in pioneering European work on the causes of disease."

https://www.ft.com/content/70e1733d-ecd9-4c8e-bd6a-54b31377ede3

Off-the-shelf CARTs

"Nevertheless, generation of autologous CAR T cell products is extremely time consuming and costly, prompting researchers to explore alternative strategies to overcome these limitations. In this issue of Nature Medicine, Mailankody et al.4 report results of part A of the phase 1 UNIVERSAL clinical trial, which evaluated ALLO-715, an allogeneic off-the-shelf anti-BCMA CAR T cell product."

#CARTcells #Immunology #Immunotherapy #NatureMedicine #MultipleMyeloma #Hematology

https://www.nature.com/articles/s41591-022-02195-2

It's hard to capture in a photo the sheer scale of Hew Locke's "Procession" at the Tate Britain - what an incredible surprise (we'd gone to Cornelia Parker retrospective, did not expect to see this at all).

More on the avian flu jump to mammalian hosts (in Spanish):

"Un estudio científico sugiere ahora que el virus de la gripe aviar saltó desde las aves silvestres a los visones y mutó en la explotación, empezando a transmitirse de mamífero a mamífero, sin llegar a infectar a los trabajadores de la granja, equipados con mascarillas."

#AvianFlu #PublicHealth

https://elpais.com/ciencia/2023-01-24/el-brote-de-gripe-aviar-en-una-granja-de-visones-espanola-enciende-las-alarmas-en-todo-el-mundo.html

"It is not just in the areas of electronics and digital technologies that Grenoble outperforms larger French cities. Grenoble Alpes University (UGA) comes fifth when French universities are ranked by the number of articles that list their researchers as authors in 82 leading natural-science journals in the year from October 2021 to September 2022 by Nature Index. Almost one in 13 jobs in the region are in research and development (R&D) — the highest proportion of all French metropolitan areas"

https://www.nature.com/articles/d41586-023-00109-x