'A direita não só está disposta a expor os portugueses a uma governação que inclui um partido xenófobo e racista, como não tem a honestidade e a lisura de o admitir. Os portugueses têm o direito pleno a saber com o que é que podem contar e as forças políticas de direita têm a obrigação de dizer a verdade sobre um assunto desta importância. É miserável este jogo de destapa e esconde.'
https://www.publico.pt/2023/01/25/opiniao/opiniao/perigoso-acreditem-2036271
“Tras secuenciar su ADN, descubrimos que sufre el síndrome de Brown-Vialetto-Van Laere, una enfermedad rara causada por una mutación en el transportador de la vitamina B2 o riboflavina”, asegura Pedro Rodríguez. Soda ha tenido suerte porque existe un tratamiento para esta enfermedad y es relativamente sencillo: tomar vitamina B2 en grandes cantidades.'
'To study TERT deregulation and its downstream consequences, we generated a Tert mutant promoter mouse model via CRISPR/Cas9 engineering of the murine equivalent locus (Tert-123C>T) and crossed it with thyroid-specific BrafV600E-mutant mice.'
#Preprint #Telomeres #telomerase
https://www.biorxiv.org/content/10.1101/2023.01.24.525280v1?med=mas
#Katherine Irwin @Katie E Irwin My first official PhD pre-print is out
today! Here, we detect TDP-43 loss
-function associated cryptic
peptides in pre-symptomatic
C9ORF72 CSF. We think that these
neoantigens could serve as early
biomarkers for ALS-FTD & other
TDP-43-related diseases https://www.biorxiv.org/content/10.1101/2023.01.23.525202v1.full.pdf
'The Financial Times has reported that, in its last year of operations before the pandemic, the restaurant typically had 34 paid cooks—and about 30 unpaid interns. Only in October, after nearly two decades in business, did Noma start paying the people who painstakingly prep and stage its food for presentation to customers.'
https://www.theatlantic.com/ideas/archive/2023/01/noma-copenhagen-fine-dining-unsustainable/672738/
Great discussion, great questions- thanks to all my speakers & our audience! Todays session was poster prize winners from EMBO Cilia 2022- more surprises next time! We will be back 🗓️APRIL 18th 2023 🗓️ for our second session #ukcilia2023- sign up here if you are not on my list! Free and open to all: https://eventbrite.co.uk/e/bscb-gensoc-uk-cilia-network-e-symposia-series-tickets-122092125835 /fin
This is important — closing Central #Madrid to cars over holidays resulted in a 9.5% boost in retail spending on its main shopping street: STUDY.
There was also a 71% drop in air pollution.
Via @carltonreid in Forbes. #citymakingmath #citiesforpeople #cities #cars #streets #urbanism #Spain
RT @nytclimate
More than 1,200 scientists and experts left the E.P.A. during the Trump administration. Most have not returned, leaving the agency in a bad spot as it struggles with some of its key mandates. https://nyti.ms/3woXKbq
RT @elowesab@twitter.com
My Lab at the Université Laval is hiring students and post-docs. Check out the poster below for more information and how to apply. Come join us in beautiful Québec City!
Friends and colleague, thank you for the retweets.
February 2023 issue of @TrendsNeuro:
https://www.cell.com/issue/S0166-2236(22)X0003-9
Free featured content & more:
https://www.cell.com/trends/neurosciences/home
On the cover:
‘Entorhinal cortex dysfunction in Alzheimer's disease’
by & Kei Igarashi
https://www.cell.com/trends/neurosciences/fulltext/S0166-2236(22)00237-5
Interesting review about the role of glycans in the mechanobiology of cancer. Stiffening of the extracellular matrix (ECM) as the major factor influencing cancer-promoting behavior: survival signaling, proliferation and migration.
'Martin Riker’s light, charming and shyly philosophical second novel, “The Guest Lecture,” details a tortured night inside the head of a young academic, an economist named Abigail. She’s sleepless because she’s an insomniac. She’s doubly wired because she must give a talk the next day, one for which she’s woefully underprepared.'
Phylogenetic analysis of SARS-CoV-2 data is difficult https://buff.ly/3XX2lwS
Genomic evidence for complex domestication history of the cultivated tomato in Latin America https://buff.ly/3XVvqZW
RT @IcomOfficiel@twitter.com
🇮🇹Italy welcomes home the return of 60 #looted archaeological #artefacts worth more than $20 million, many of which had been on display at New York's Metropolitan Museum of Art @metmuseum@twitter.com before their illicit origin was discovered I @Reuters@twitter.com ⌨️ https://ecs.page.link/7HFCg
'Three years into the global fight against SARS-CoV-2, the arsenal to combat long COVID remains depressingly bare. Being vaccinated seems to reduce people’s chances of developing the condition, but the only surefire option for avoiding long COVID is to avoid catching the coronavirus at all—a proposition that feels ever more improbable.'
More on the avian flu jump to mammalian hosts (in Spanish):
"Un estudio científico sugiere ahora que el virus de la gripe aviar saltó desde las aves silvestres a los visones y mutó en la explotación, empezando a transmitirse de mamífero a mamífero, sin llegar a infectar a los trabajadores de la granja, equipados con mascarillas."
"Here, we present data on preclinical studies in mice of a receptor-binding domain (RBD)-based recombinant protein vaccine candidate (PHH-1V) consisting of an RBD fusion heterodimer comprising the B.1.351 and B.1.1.7 SARS-CoV-2 VoCs formulated in SQBA adjuvant, an oil-in-water emulsion."
I've worked on all of science, from B cells to T cells.
https://fellowsherpa.com