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At the start of the 2020 global #pandemic, Biologic Models participated with a team of international research scientists examining the structural proteins of 2019 novel #Coronavirus. Created from that research is this #3Dprint of #SARSCoV2 Virion. biologicmodels.com/viruses/sar @mstdn.science

** Global Symposium 7 is tomorrow! **

Beyond the SNP: Structural Variants and Repetitive DNA in Genomics and Evolution

bit.ly/40Nejvz

Access instructions were emailed to all registered members yesterday.

See you on Gathertown!

@SMBEmeetings

'Saura reunió una obra fotográfica con miles de negativos que quizás sea ahora buena ocasión para mostrar una completa relectura. Autodidacto, con solo 19 años expuso las fotos tomadas con una Rolleiflex en la Real Sociedad Fotográfica de Madrid.'

elpais.com/cultura/2023-02-14/

Sagy et al. have recently published in an analysis of the real-world efficacy of , the shot redeployed against .
nature.com/articles/s41591-023

Last Fall I wrote a column for Nature Medicine that touched on the FDA's Animal Rule, used in the approval of anti-smallpox drugs due to the difficulty in designing ethically acceptable efficacy screens.

nature.com/articles/d41591-022

"The IBRO Parenthood Grant aims to support early-career Principal Investigators who are approaching parental leave (either via birth or adoption) by providing supplemental laboratory funding."

ibro.org/parenthood-grants/

C'est désormais confirmé. Avec une analyse de plusieurs centaines de milliers de tweets, des chercheurs confirment que des antivax/complotistes répandent des discours climatosceptiques depuis plusieurs mois.

Explication dans cet article, à partager un maximum svp !

bonpote.com/comment-les-antiva

"Among the things Florida objected to: the course’s discussions on reparations, queer studies, feminist thought and intersectionality – referring to the way various systems of oppression are interconnected."

theguardian.com/education/2023

"I always think about climate justice as multitasking. We live in a time of multiple overlapping crises: we have a health emergency; we have a housing emergency; we have an inequality emergency; we have a racial injustice emergency; and we have a climate emergency, so we’re not going to get anywhere if we try to address them one at a time. We need responses that are truly intersectional. So how about as we decarbonise and create a less polluted world, we also build a much fairer society on multiple fronts?"

theguardian.com/books/2023/feb

'Two weeks after the last dose, antibodies to P. falciparum circumsporozoite protein and PfSPZ were higher in protected versus unprotected vaccinees. A three-dose regimen of PfSPZ Vaccine demonstrated safety and efficacy against malaria infection in malaria-experienced adults.'


science.org/doi/full/10.1126/s

'Molecular glue degraders are defined as the compounds leading targeted protein degradation (TPD) by creating novel ligase-substrate interactions. Here, we identified AK59 as a novel molecular glue degrader for STING.'

biorxiv.org/content/10.1101/20

'Determined to catch up, Japan is ramping up a 1.1 trillion yen ($8.5 billion) initiative that aims to give Japan the capability to develop a vaccine for a new virus in 100 days, a goal being adopted by many countries.'

science.org/content/article/ja

Work from the group employing analysis of large datasets to identify recurrent sequences and public CD8 TCR clones associated with durable responses to #cancer immunotherapy in patients with #melanoma. #immunology #cancer #oxford
biorxiv.org/content/10.1101/20

Public health in 21st century America.

"Mississippi’s woes are an acute example of a larger public health failure that is reprised nearly every time a major health threat grabs headlines. The problem, experts say, is that Congress starves state and local health agencies of cash for even basic needs in quiet times."

nytimes.com/2023/02/13/us/poli

"We children of the Boomers went into the workplace with a double expectation – we wanted a proper occupation, and we wanted it to be a vocation. And once again, science seemed to fit the bill."
@TIR_scienceblog

totalinternalreflectionblog.co

New posting! This asks whether in have evolved from a hobby, to a , to a profession...and maybe now into a job (and how that's probably a good thing).

Funnily, when I first conceived of this posting (quite a way back) I thought it would be a negative one about how people don't care enough any more, but that has almost completely turned around - I now think it's a good thing if people are stepping back. A good /life_balance isn't something to whine about - we should be insisting on it.

Anyhows, read the posting and see what you think... ;-)

totalinternalreflectionblog.co

The Bibliographical Society of America is seeking to build an endowment to support the Dorothy Porter Wesley Fellowship. The Fellowship of $3,000 is awarded each year to a Black individual for research on any topic. Thanks to a gift from Lisa Unger Baskin, the fund is halfway to its goal of $85,000, but it needs our help to make it the rest of the way. bibsocamer.org/support-bsa/por

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