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'Hace tres meses, un hospital de Londres anunció que había utilizado los editores de bases para salvar la vida de Alyssa, una niña de 13 años con una leucemia muy agresiva.'

elpais.com/ciencia/2023-03-28/

"Greater surveillance testing of staff members at skilled nursing facilities was associated with clinically meaningful reductions in Covid-19 cases and deaths among residents, particularly before vaccine availability."

nejm.org/doi/full/10.1056/NEJM

'Since her report went online last week, Débarre has been the subject of abuse and conspiracy theories circulating online, largely among people who support the theory the virus emerged from a leak from the Wuhan Institute of Virology, located about 30 minutes away from the market. “I’m not living the best days of my life right now,” she says.'

theguardian.com/world/2023/mar

"Houve tempos em que políticos de extrema-direita portugueses apregoavam ideários neofascistas, colonialistas e racistas contra a maré. Eram bons tempos. Dizia-se que cá o mal não pegaria; que estávamos imunes ao que assistíamos noutros países."

publico.pt/2023/03/29/opiniao/

#IDMastodon #antiboticresistance @ScienceMagazine Genomic analysis of 51,229 #Mycobacteriumtuberculosis clinical isolates has identified an essential transcriptional regulator, Rv1830, herein called resR for resilience regulator, as a frequent target of positive (adaptive) selection. resR mutants do not show canonical drug resistance or drug tolerance but instead shorten the post-antibiotic effect
science.org/doi/epdf/10.1126/s

"People with drug-resistant tuberculosis in India could soon have access to critical medication at a far lower cost after the authorities rejected US pharmaceutical giant Johnson & Johnson’s application to extend a patent."

theguardian.com/global-develop

'But vaccine opponents on the internet, who somehow assumed that a COVID shot was responsible for my son’s death, thought my family’s pain was funny. “Lol. Yay for the jab. Right? Right?” wrote one person on Twitter. “Your decision to vaccinate your son resulted in his death,” wrote another. “This is all on YOU.” “Murder in the first.”

theatlantic.com/ideas/archive/

RT @Hui_Hui_Zhang
My paper with @luohuan_huan is just out in @PLOSBiology ! We find that feature-specific reactivations of past information can bias the present feature representation, thereby mediating repulsive (sensorimotor features) and attractive serial biases (abstract category choice). twitter.com/plosbiology/status

"In recent weeks, ministers in Netanyahu’s government have dined with a convicted member of an organized-crime family, insulted the United Arab Emirates, and called to “wipe out” a Palestinian village. None of these individuals was publicly reprimanded by the prime minister. Gallant, by contrast, was promptly fired for questioning the judicial-reform plan."

theatlantic.com/ideas/archive/

“You have got a whole system failure here that is registering itself in suicidal kids,” Dr. Carlson said. Parents seeking care for children, she said, encounter a series of frustrations: Clinicians who don’t take insurance or aren’t taking new patients; crisis interventions staffed by low-paid, poorly trained workers; insurers that don’t reimburse well.'

nytimes.com/2023/03/28/health/

#Interferon-inducible #phospholipids govern #IFITM3-dependent #endosomal #antiviral immunity

#Phosphatidylinositol(3,4,5)-trisphosphate enhances inhibition of #endocytic viral entry via binding to the intracellular loop of interferon-induced transmembrane protein 3

Anna Kajaste-Rudnitski, Giulia Unali et al

embopress.org/doi/10.15252/emb

'As the Nazis took over, the artwork — by Gustave Courbet, the French realist painter — was carried off and reserved for the collection of a top Nazi official, while the engineer, Robert Bing, joined the French Resistance, working to distribute clandestine newspapers on behalf of the movement.'

nytimes.com/2023/03/28/arts/co

RT @GladstoneInst
Meet Ritu Kumar, director of Gladstone's stem cell core. In this interview she talks about her work, why she loves working at Gladstone, and her hopes for the future of women in STEM. #WomensHistoryMonth
bit.ly/40ebcvT

Had no idea the large blue, a pretty butterfly that used to be quite common in the UK, was an ant brood parasite: en.wikipedia.org/wiki/Large_bl

"Wild Isles", featuring David Attenborough, made a great video shoot of its life cycle.

At #iNaturalist there are observations only in the South West of the UK: inaturalist.org/taxa/109281-Ph

"The revenue model of mega-journals is based entirely on charging article publication fees. The publishers increase these fees when a journal improves its impact factor ranking. The model secures high journal revenue but poses difficulties for authors with limited discretionary funds."

jamanetwork.com/journals/jama/

Changing the amount of specific helper molecules in the cell controls the rate of the metabolic reactions that power life. elifesciences.org/digests/8437

'The COVID-19 pandemic has had a disproportionate impact on mothers in academic science, bringing long-standing issues to the fore. A study done during the very early stages of the pandemic found that scientists with at least one child aged five or younger were spending 17% less time on research than they had previously'

nature.com/articles/d41586-023

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