Thiago Carvalho @cyrilpedia@social.cleverlibre.org

RFI: "Needs and Challenges in Obtaining and Testing Clinical-Grade RNA-based Cancer Vaccine Formulations to Support Translational and Clinical Research"

https://grants.nih.gov/grants/guide/notice-files/NOT-CA-23-063.html

In vetebrate embryos, the notochord induces foreplate, which then acts as an organiser to pattern the neural tube

Surprisingly, FP organisers emerge spontaneously in neural tube organoids that have no notochord

HOW ON EARTH do they do this?!

Krammer et al now tell us that
scattered FP cells undergo BMP-mediated “cluster competition’ to generate a stable ‘winning” foreplate.

A soothing #PaperThemeTune from Cluster with Brian Eno https://www.youtube.com/watch?v=nsnLPfim2Og

https://www.biorxiv.org/content/10.1101/2023.06.25.546258v1

#DevBio

#Introduction

Hello #BiologyMastodon

I'm a prof of stem cell and developmental biology in Edinburgh. I'm here to hear about your interesting research
#DevBio #StemCells

I rather like our planet, and I'm co-founder and Chair of the Sustainable Conferencing Initiative at the Company of Biologists
#SustainableConferencing #SustainableScience

I also love music, and if I like your paper I might suggest a theme tune for it
#PaperThemeTune #music

Author 1: I think you should replace reference 45 with an older reference about heat stress in yeast.
Author 2: OK
Preprint:

Introducing #OpenAccessWednesday 🔓 @BiologyOpens new weekly showcase of a recently published #OA article. This week features Graham Turnbull and colleagues
@EdinburghUni
correlation of climbing efficiency to critical morphological features.
https://journals.biologists.com/bio/article/12/5/bio059874/310404/The-influence-of-claw-morphology-on-gripping

Isabel Gordo: É uma das grandes cabeças da sua geração. Investigadora Principal da Gulbenkian Ciência, dedicou os últimos anos à evolução microbiana.
https://expresso.pt/podcasts/geracao-70/2023-06-28-Isabel-Gordo-Os-meus-pais-tinham-a-4-classe.-A-minha-mae-era-cabeleireira-e-o-meu-pai-tinha-um-talho.-Sacrificaram-se-para-eu-estudar-e2899faa

Accelerating Open Modification Spectral Library Searching on Tensor Core in High-dimensional Space | https://academic.oup.com/bioinformatics/advance-article/doi/10.1093/bioinformatics/btad404/7208862?login=false #proteomics

Hey there,

Someone kept bringing up Mastodon so I decided to join. Y'all can just call me Collard Green Dreams, or CGD for short. Here are some relevant things about me:

I'm African-American
I'm Bi and Non-Binary
I'm pretty sure I have ADHD, Autism, or both
I have a ton of interests that vary, such as VNs, books, film, vampires, ATR, history, science, and food.

Nice to meet y'all 🙂

#introduction

'Era una mujer sin nombre, de pie sobre una barricada en la Barcelona de 1936, una bandera rojinegra detrás. La imagen se imprimió en carteles y libros, se pintaron murales, y ella se convirtió en un icono de la Guerra Civil. Se desconocía su identidad. Y la del fotógrafo.'

https://elpais.com/cultura/2023-06-27/la-miliciana-ya-tiene-nombre-anita-garbin-alonso-costurera-exiliada-anarquista.html

In flies:

"Using a transcriptomic analysis of over 37,000 nuclei, we identified twelve distinct clusters of cells corresponding to temperature-sensing arista neurons, humidity-sensing sacculus neurons, and support cells relating to these neurons."
#Preprint #SensoryNeuroscience #neuroscience

https://www.biorxiv.org/content/10.1101/2023.06.26.546511v1

Every microbiologist’s nightmare… https://www.cnn.com/2023/06/27/us/janitor-alarm-freezer-rensselaer-polytechnic-lawsuit-new-york/index.html

Lately I have been visiting 🐦 more freq than once a week to engage with ramble chats (and #marblefacts) with my colleagues and friends post a great conference. I miss that banter, but that's the *only* thing

#Twitter as I knew it is a long lost memory. As I opened it I got inundated by ads and random posts from accounts I have no clue or care about.

I love my 🦣 home very much, full of interesting posts and people and *so* civilized, I just wish my #glycotime peeps could move over 😊

Is there N6-methyl-2’adenine DNA incorporation derived from decay of #m6A-RNA in cells?

Hailin Wang and colleagues show that mammalian ADAL deaminase sanitizes 2’-#deoxynucleotide pools to prevent AK1-dependent misincorporation

https://www.embopress.org/doi/10.15252/embj.2023113684

Involving patients in infection research. Important - it's about/for them, ultimately.

#cdiff example here in @ESCMID #PPI #IDMastodon #MedMastodon #patients #research #infection
https://www.clinicalmicrobiologyandinfection.com/article/S1198-743X(23)00305-1/fulltext?dgcid=raven_jbs_aip_email#%20

Holy crap, the excellent @glycojones has a postdoc job available. If you like biology, coding, sugars, and structures - this looks like a great role where you can _really_ enrich existing Alphafold models of extracellular proteins.

Also, York is pretty dope.

#Glycotime #StructuralBiology

Jobs - The University of York
https://jobs.york.ac.uk/vacancy/research-associate-529961.html

There's a tenure-track research position opening at CBIO in Paris. Come work with us on #machineLearning for #biology and #medicine!

I too wish it was a permanent, civil servant position from the get-go... but the position turns into a permanent contract after two years and a very reasonable review process.

Details: https://cbio.mines-paristech.fr/pdf-files/tenure-track-position-cr-artificial-intelligence-for-biology-and-medicine

Feel free to reach out informally if you have any question!

#bioinformatics #academicJobs #academicMastodon