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Oubliette Exhibition at Biblioteca Camoes, Lisbon (Largo do Calhariz, 17). Show runs until the end of June (AKA Tomorrow!).

"The Pignerol Gates. (Rome, circa 1760).
Oubliettes have only one entrance – frequently a trap door on the roof, as was by all contemporary accounts the case of the Pignerol cell. They were constructed so that men could be literally thrown away and forgotten. In Pignerol we know for certain that the gate opened once in 1631 and then again in 1670. The plates you see here were etched in 18th century Rome, by an unknown hand, working from the sketches produced by the guards (the documents were then in the Vatican’s possession, they were transferred to Napoleon by Pius VII and are now in the Archives Nationales)."
Prof. Horst Manfrenjensenden, Ph.D.
Head of Collections, von Willebrand Trust.

#ArtGallery

@anaanajottajotta @consta_arouca @madparreira@jorgenesbitt

On this day in 2018: Arvid Carlson died, won #2000 NobelPrize for discovering signal transduction in nervous system #NobelPrize #ThisDayInBiotech

The one thing Google always did pretty well was "Search". Now, quality websites are being relegated further and further down the results page, replaced by more and more sponsored sites and YouTube links (again, delivering Ads). Of course the situation will become even worse when the presence of AI becomes fully integrated into Search. How will a small business, with a good website get noticed? Presumably the plan is for us all to pay more and more. Well sod that!

I think what may happen is that, as Google Search becomes less and less relevant, there will be a migration to fast and relevant, alternative search providers. This is already happening to some extent.

I have been using open source (auditable), non tracking search providers using the "SEARX" software for a while now. I can join a public server or even start up my own server on my computer. Already an improvement on Google without the Ads and tracking.
https://searx.github.io/searx/

I am also testing out a "paid" search option called Kagi https://kagi.com/ . For a small monthly fee (businesses have to monetise somehow) you can have your search results any way you like, ad and tracking free. Personally, I am happy to pay $5 a month to get speed, relevancy and answers to my internet searches.

Anyway, interesting times.

#Google #Search #Searx #Kagi

#OtD 29 Jun 1879 Pedro Vallina Martinez, Spanish anarchist doctor and civil war fighter, was born. Jailed and exiled by the Spanish state, when the revolution came he organised militia groups and worker-controlled health service libcom.org/history/vallina-ped

Looking to use quantitative bioimaging in your experiments? Our new Essay from @bethcimini &co provides a navigational guide for biologists new to quantitative bioimaging, with recommendations and pointers to open source resources. #microscopy #PLOSBiology
plos.io/3JCd3Et

29 June 1937 | A Dutch Jewish girl, Betty van Aalst, was born in Amsterdam.

In February 1944 she was deported to Auschwitz with her brother Simon (in the picture). They were murdered in a gas chamber after the selection.

#Auschwitz #Birkenau #Holocaust #Shoah #Jews #history #histodons #Nazis #Germany #NeverForget #ww2 #Memorial #Remember #memory #otd #facts

Forces from enveloping basement membranes shape the tissues they envelop. In the Drosophila egg chamber, basement membranes alter the migration of cells through the tissue, connecting membrane #biomechanics to migration via constriction and cortical tension. #PLOSBiology
plos.io/46pGIum

New #PLOSBiology study reveals that MLL and SETD1A regulate transcription and H3K4 methylation on centromeres to ensure kinetochore maintenance and CENPA deposition to ensure centromere stability. #epigenetics
plos.io/3NDt7aq

Improve your coding skills: Learn more about computing tools such as programming (R, Julia), literate programming (Quarto), version control (Git).

Apply before July 17 for the Open Science Summer School: malikaihle.github.io/OSC-Open-

#OpenScience

Drosophila carry a wide range of specialized sensory organs on the foreleg tarsus; a single-cell atlas of this tissue during pupal development reveals the genetic differences between different sensory organs #neuroscience #PLOSBiology
plos.io/3NzzGKK

In this latest 'Transitions in development' interview, Reviews Editor @amjeve speaks to Evgeny Kvon about his career and the silver lining to starting a lab during the COVID-19 lockdowns:

journals.biologists.com/dev/ar

'Zhang et al. provide crucial insights into the mechanisms driving the transition from the onset of autoimmunity to joint destruction in rheumatoid arthritis. The findings emphasize the central role of myeloid monocytes that overexpress both RANK and TLR2, and the sialylation of TLR2 in driving the fusion of monocytes and consequent resorption of bone.'

elifesciences.org/articles/897

National Centres of Competence in Research (NCCRs) are long-term research projects of the highest quality on topics of strategic importance for Switzerland. In the second half of November 2023, the SNSF will publish the sixth NCCR call.
sohub.io/hfae

Foundational and I'd say still unsurpassed as a history of the birth of molecular biology.

'Around that time, the late 1970s and very early 1980s, I became much more interested in nonfiction, especially nonfiction about science, and found myself reviewing such books for The Christian Science Monitor: the letters of Robert Oppenheimer, for instance, and a book of memoirs by Carl Friedrich von Weizsäcker, and a magnificent book (more magnificent than I was capable of appreciating then) on the foundational history of molecular biology, The Eighth Day of Creation, by Horace Freeland Judson.'

nybooks.com/online/2023/06/24/

New article! Read Multicomponent intranasal adjuvant for mucosal and durable systemic SARS-CoV-2 immunity in young and aged mice nature.com/articles/s41541-023 in npj Vaccines

Last few days to send us your proposal for our #BiologistsWorkshops programme. You focus on the science, we'll focus on the funding and logistics. Submit your topic idea by 30 June at biologists.com/workshops/propo

'La inmensa mayoría de los físicos e ingenieros que participaron en el proyecto Manhattan eran pacifistas, progresistas y ninguno creía que la bomba se fuera a lanzar contra la población civil. Algunos de ellos, cuando entrevieron las intenciones de los militares y el presidente Truman, pagaron su oposición con algo más que represalias.'

elpais.com/ciencia/2023-06-29/

Meanwhile, at the Bad Place

'The former NBCUniversal advertising head, who started as chief executive on June 5, is seeking to launch full-screen, sound-on video ads that would be shown to users scrolling through Twitter’s new short-video feed, according to three people familiar with the situation.'

ft.com/content/5a792427-5ca0-4

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