Thiago Carvalho @cyrilpedia@social.cleverlibre.org

Marie Sklodowska Curie died July 4, 1934, from leukemia, caused by exposure to high-energy radiation from her research. The mineral Ewingite is found in the same region (Czech Republic) where uranium ore was mined for the Curie’s groundbreaking studies of #radioactivity ☢️💎
#MineralMonday

Congrats to the new EMBO members !!

https://www.embo.org/press-releases/embo-announces-election-of-new-members/

We're noticing a lot of movement to Mastodon. To get you started, here's a list of #OpenScience folks who are already on Mastodon 🐘 https://germanrepro.github.io/Mastodon-OpenScience/

More information regarding the raw meat which tested positive for H5N1 bird flu in Poland 🇵🇱:

The sample that showed the presence of H5N1 belongs to a woman living in Chełmek. She bought the chicken breast meat she gave the cat on June 9 in one of the stores of a large chain.

Our paper is out in
Current Biology
🎉🎉
Congrats Sushila & co-authors!

Read more to find out how an oncogene impacts mitotic substrate attachment leading to out-of-plane cell divisions:

https://www.cell.com/current-biology/fulltext/S0960-9822(23)00723-6

In our new preprint we characterise neuropeptide signalling in the cnidarian #Nematostella.
https://www.biorxiv.org/content/10.1101/2023.07.03.547448v1
Daniel Thiel and Luis Yanez-Guerra screened 64 neuropeptides against 161 G-protein coupled receptors (#GPCR) and found activating peptide ligands for 31 receptors.
#cnidaria #neuropeptide #evolution #neuroscience

It can be a bit disappointing when the mutant is just like the wild-type, but one can look at the bright side, it's just as beautiful as the wild-type. #DevBio #DevelopmentalBiology #CellBiology #CellBio #AsymmetricCellDivision #Celegans #Embryo

Automatic Differentiation is no Panacea for Phylogenetic Gradient Computation https://doi.org/10.1093/gbe/evad099 #science #evolution #biology #genome #evolgen_paper

On #TechnicalTuesday we are highlighting work by Nevena Stajković, Ivana Nikić-Spiegel, et al. on click labelling in neurons. They design AAV vectors to add unnatural amino acid-based tags to their target proteins and use SPIEDAC for labelling with small dyes.
@J_Cell_Sci https://journals.biologists.com/jcs/article/136/12/jcs260600/320411/Direct-fluorescent-labeling-of-NF186-and-NaV1-6-in

Interested in epithelial cell division?
Delphine Delacour is starting up her team at IBDM, Marseille, France
and is recruiting a post-doc!
Superb lab and exceptional multidisciplinary scientific environment!
contact: delphine.delacour@univ-amu.fr

Variants in FOXP4, the 1st gene identified to be associated with #LongCovid, from over 6,400 cases and >1 million controls
https://medrxiv.org/content/10.1101/2023.06.29.23292056v1

#IDMastodon #opthalmology @aao_ophth Retinal tissue & microvasculature loss in #SARSCOV2 infection .4 Ways #COVID Leaves Its Mark on the Eye
📌 https://www.aao.org/eye-health/tips-prevention/covid-damages-retina-eye-stroke-pinkeye#:~:text=Doctors%20are%20still%20learning%20how,blood%20vessels%20of%20the%20eye
📌 https://www.nature.com/articles/s41598-023-31835-x

Interesting article on so-called "long vax", rare long-COVID-like syndrome linked to COVID vaccines.

Risk clearly far lower than getting longCOVID from COVID itself (which everyone will of course get at some point), really hard to convincingly demonstrate a connection, and I worry about confounders here. Plus of course anti-vaxxers will try to make hay.

But as Harlan says, as a scientists there's "an obligation to have an open mind". https://www.science.org/content/article/rare-link-between-coronavirus-vaccines-and-long-covid-illness-starts-gain-acceptance

“What, to the slave, is the Fourth of July?”
-Frederick Douglass #4thofJuly #july4th

Full speech here, delivered July 5, 1852: https://bit.ly/3JM6UWj #BlackMastodon #Mastodon

Issue 12 is complete

Our cover image shows click-labelled NF186 in neuroblastoma cells. Cells expressing three different NF186 constructs overlaid in one image. See article by Stajković et al.
https://journals.biologists.com/jcs/article/136/12/jcs260600/320411/Direct-fluorescent-labeling-of-NF186-and-NaV1-6-in
Also in Issue 12
- Research Highlights on Ivy1 in the endolysosomal system, proximity proteomics with Rab4 & Rab11 and neuronal microtubules.
- Article & Poster on viral evasion of the interferon response
- Review on p300 in autophagy

Explore our ToC here: https://journals.biologists.com/jcs/issue/136/12

By phylogenetic reconstruction, Daniel Thiel and Luis Yanez could show that #cnidarian #neuropeptide receptors diversified independent from #GPCRs in bilateria. This parallel #evolution and expansion confirms that cnidarians do not represent the ancestral state in neuronal signalling (as implied by terms like 'pre-bilaterian') any more than bilaterians.
#receptor #evolution #neuroscience #phylogeny