Thiago Carvalho @cyrilpedia@social.cleverlibre.org

#IDMastodon @thelancetinfdis Few trials have compared homologous and heterologous 3rd doses of #COVID19 vaccination with inactivated vaccines & mRNA vaccines. Aim to assess immune responses, safety, efficacy against #SarsCoV2 infection following homologous or heterologous 3rd-dose #covid19vaccination with either one dose of CoronaVac inactivated vaccine or BNT162b2 mRNA vaccine).
https://www.thelancet.com/journals/lanmic/article/PIIS2666-5247(23)00216-1/fulltext

a remarkable fact in this great piece by devi sridhar - in 1971, 400 Dutch children died in traffic accidents. In 2021, after safety campaigns and decades of active travel infrastructure investment, child traffic deaths were 17 #cycling #activetravel https://www.theguardian.com/commentisfree/2023/aug/04/uk-must-follow-europe-lead-prioritising-walking-cycling-public-transport

'We detected frequent introductions of multiple SARS-CoV-2 lineages in white-tailed deer, which subsequently became enzootic and co-circulated, and certain lineages persisted in white-tailed deer even after their decline in human populations. In addition, three cases of potential spillover from white-tailed deer back to humans were identified.'

https://www.nature.com/articles/s41467-023-39782-x

'According to Calvino, literature will continue to flourish in the next one thousand years and these six lines of literary heritage will expand far and wide. I have always liked Calvino and after reading this book, I like him even more.'

https://lithub.com/wang-xiaobo-on-the-limitless-mind-of-italo-calvino/

Important reporting by Christopher Mathias. Same shit, different day. "Richard Hanania, a visiting scholar at the University of Texas, used the pen name...to write articles where he identified himself as a “race realist.” He expressed support for eugenics and the forced sterilization of “low IQ” people, who he argued were most often Black."

https://www.huffpost.com/entry/richard-hanania-white-supremacist-pseudonym-richard-hoste_n_64c93928e4b021e2f295e817

'Proliferating cell nuclear antigen is critical to DNA replication and repair processes. Through a rational drug design approach, we identified a small molecule PCNA inhibitor, AOH1996, which selectively kills cancer cells.'
#Cancer

https://www.cell.com/cell-chemical-biology/fulltext/S2451-9456(23)00221-0

"COVID-19 mRNA vaccination in pregnant people aids in preventing maternal SARS-CoV-2 infection and reduces risk of common adverse birth outcomes, with the booster conveying additional protection. We therefore recommend that pregnant people not only be vaccinated against COVID-19, but also stay up to date with their vaccination schedule."
#COVID #Covid19

https://www.thelancet.com/journals/landig/article/PIIS2589-7500(23)00093-6/fulltext

Tales from the trenches of scientific publishers, back in the 1980s:

"Oh my dear, you have no idea. I spent several years in the 80s as assistant managing editor of a top peer-reviewed medical journal, and what I learned is that profit is the only thing that matters. In the space of a single year, the number of issues and the number of pages per issue were doubled, even as several of the issues were given over entirely to advertising for specific drugs, all without any of the people holding medical degrees -- the titular editor or the peer reviewers or the subscribers -- making a single objection.

The journal was one of 20 technical journals owned by financial advisors Dun & Bradstreet, sold shortly afterward to Reed International, another similar firm. The front offices looked lush, but the editing was done in a warren of mostly windowless rooms by young women with zero medical training. Most of what we did was harass the actual doctors who were supposed to do the peer review, because they didn't care enough to meet deadlines, and then copy edit their barely readable responses to make them meet minimal editorial standards. And nobody noticed the product was shit. The subscriptions were paid automatically by corporations, the issues went straight onto shelves in those offices where they served as decoration. As far as I could tell, the only people other than the primary authors of the studies who ever read those studies and reviews were me and my co-workers.
Escaping that place to work in a serious news organization was the best decision I ever made, even if it involved taking a more than 50% salary cut." – by "AngelaMotorman" at https://old.reddit.com/r/todayilearned/comments/11ymxtq/til_in_1982_scientists_resubmitted_published/jd8lcjq/

#ScientificPublishing #academia #publishing

New research showing how different #Covid19 variants affect the brain.

The original Wuhan #SARSCoV2 damaged the widest range of brain cells and disrupted the integrity of the blood-brain barrier

https://www.crick.ac.uk/news/2023-08-04_scientists-begin-to-untangle-how-covid-19-affects-brain-cells

Research Associate - Evrony Lab (NYU)

NYU - Evrony Lab

Come do exciting science at the Evrony Lab (NYU) as a Research Associate

See the full job description on jobRxiv: https://jobrxiv.org/job/nyu-evrony-lab-27778-research-associate-evrony-lab-nyu/?feed_id=53658

#ScienceJobs #hiring #research #genomics
New York City #UnitedStatesUS #ResearchTechnician
https://jobrxiv.org/job/nyu-evrony-lab-27778-research-associate-evrony-lab-nyu/?feed_id=53658

"Gov. DeSantis’ threat to ‘start slitting throats’ of federal employees is dangerous, disgusting, disgraceful, and disqualifying,” says AFGE President Everett Kelly. “No federal employee should face death threats from anyone, least of all from someone seeking to lead the U.S. government.” https://www.govexec.com/management/2023/08/desantis-vows-start-slitting-throats-federal-workers-day-one-presidency/389093/

How to prepare for the heat by the London Underground.