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"These findings indicate a discrepancy in the approval policies between the FDA and EMA and imply either that some patient groups in the USA do not get access to relevant medical treatment, or that some patient groups in the EU are treated with medicine without a positive benefit–risk balance."

thelancet.com/journals/lanonc/

Haplotype independence contributes to evolvability in the long-term absence of sex in a mite biorxiv.org/content/10.1101/20

"It is time to effect a revolution in female manners - time to restore to them their lost dignity. It is time to separate unchangeable morals from local manners."
Vindication of the rights of woman

Mary Wollstonecraft died #OTD in 1797. She is best known for A Vindication of the Rights of Woman (1792), considered a classic of feminism, in which she argues that women are not naturally inferior to men but appear to be only because they lack education.

gutenberg.org/ebooks/author/84

#books #literature

'It makes sense that Kennedy Jr. and Donald Trump are effectively in alliance, and that Trump as president contemplated appointing Kennedy to head a putative “vaccine safety and scientific integrity commission.”

nybooks.com/online/2023/09/07/

'Cooke had always admired Bob Dylan’s civil rights song “Blowin’ in the Wind”. He pulled it straight into his own live repertoire, but still, as biographer Daniel Wolff wrote, something troubled him: “Geez, a white boy writing a song like that?” A 2005 biographer, Peter Guralnick, said that Cooke was “almost ashamed not to have written something like that himself”.
(photo © Jess Rand/Getty)

ft.com/content/8b88324c-4752-1

One in every four Europeans is currently in a "precarious" financial situation because of rising inflation figures, a new survey has found.

The study found that difficult financial constraints fueled by inflation have made Europeans cut off meals and consider themselves in a "precarious" condition.

euronews.com/2023/09/09/one-in

#Europe #Inflation #CostOfLiving #PersonalFinance

In case you missed it: Matthias Tschöp told me the story of the science behind the popular new class of anti-obesity drugs.

Listen to "Obesity is a Brain Disease" 🎧 👇

open.spotify.com/show/5tiWyc9z

🔬First Mastodon post alert!☺️
Hey there, I'm Delnia, and I've just embarked on my PhD journey in Cellular and Structural Biology at IGBMC, University of Strasbourg.🧬
I'll be focusing on unraveling the (ultra)structural mysteries of Golgi organization under the expert guidance of Florian Fabler. 🧪🔍
A repost would be fantastic as I'm building my network here on Mastodon.
Let's connect and explore the world of science together!
#phdlife #CellBio #cryoET #IGBMC #structurebiology #introduction

Learnt representations of proteins can be used for accurate prediction of small molecule binding sites on experimentally determined and predicted protein structures | biorxiv.org/content/10.1101/20 #proteomics

"The importance of conformational ensembles to IDR function, coupled to the inherent sensitivity of IDRs to their physicochemical environment, gives rise to the possibility of IDRs acting as molecular sensors of their surrounding physicochemical environment"

sciencedirect.com/science/arti

New paper out, & it's SO COOL!! 🤩 How different #metastasis affects 🧠 #LFP? We saw that each type have spectific signatures, so that they can be even classifed from the recordings! 😱 Thanks Alberto, Mariam, @LMPrida & Manuel Valiente for all 😊 sciencedirect.com/science/arti

'Many patient-advocacy groups are lushly funded: last year, the Alzheimer’s Association’s revenue was about half a billion dollars. A study in The New England Journal of Medicine found that at least eighty-three per cent of the largest groups receive money from pharmaceutical companies. “H.I.V. activism was a true grassroots movement, not one funded by drug companies,” Daniel Carpenter, the author of “Reputation and Power,” a colossal history of the F.D.A., told me. “I don’t want to say everything since then has been astroturfed. But companies do learn the lesson of ‘Oh, that’s how you get a drug through the F.D.A.’'

newyorker.com/magazine/2023/06

⚡️Putin's Flight Plight: @RyanAir Exception.

Ruschia / Belarus established the precedent of forcing an aeroplane in its skies to land. Then apprehending two of the passengers and subjecting them to untold tortures.

Putin can't and never will again fly over ANY ICC signatory. mastodon.world/@decodingtrolls

In case you don’t believe the same equations govern #motion in the #atmosphere and the #ocean.

Video by Tristan Heth in Tenerife, Canary Islands, Spain.

'The universal and enthusiastic welcome to Thursday’s news that Britain was to rejoin the £81bn EU Horizon programme for scientific collaboration, albeit as an associate member, was a surprise – not least to the prime minister, who had dragged his feet for months in fear of the reaction of his Europhobic right.'

theguardian.com/commentisfree/

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