Thiago Carvalho @cyrilpedia@social.cleverlibre.org

'The AACR Maximizing Opportunity for New Advancements in Research in Cancer (MONARCA) Grant for Latin America represents an AACR initiative to address this need by promoting and supporting early-career investigators in Latin America to establish a successful career path in cancer research, thereby increasing and sustaining a cadre of talented cancer researchers in Latin America.'

https://www.aacr.org/grants/aacr-monarca-grant-latin-america/?utm_medium=linkedin&utm_source=social&sf181218003=1

'But doctors say some people seek out these drugs to lose as much weight as possible — and are dismayed and disillusioned when they stop. Some go off the drugs after they hit their plateau. When they do, they tend to regain the weight they lost.'

https://www.nytimes.com/2023/09/18/well/ozempic-weight-loss-plateau.html

Origami map

https://madalenaparreira.com

'Candida auris is also on the World Health Organization’s list of priority pathogens. Last year, it said that there were “only four classes of antifungal medicines currently available, and few candidates [are] in the clinical pipeline. Most fungal pathogens lack rapid and sensitive diagnostics and those that exist are not widely available or affordable globally”.

https://www.ft.com/content/65c36ed2-0fac-479b-9bad-73c471d3929a

'What distinguishes these new books isn’t just what they tell us about an extinct sub-species of humans, but the surprising passion they bring to their subject. Their authors are enraged that popular ideas about the Neanderthals lag so far behind the cutting edge of paleontological research – research that has brought the Neanderthals closer to us than they have been in 40,000 years.'

https://www.theguardian.com/science/2023/sep/19/justice-for-neanderthals-what-the-debate-about-our-long-dead-cousins-reveals-about-us

'I am revisiting these haunts, too, because I am reading Another Country for the second time, some thirty years after my first journey through its pages. As I do, I am struck by how the novel goes against many of the fictional strategies so often adopted in our commercially driven, MFA-centered literary world.'

https://lithub.com/the-many-lessons-from-james-baldwins-another-country/

'Full exploitation of the natural reservoir of CRISPR-Cas nucleases from prokaryotes for genome editing is limited by the suboptimal activity of these enzymes in mammalian cells. Here we developed a Eukaryotic Platform to Improve Cas Activity (EPICA) to steer weakly active Cas9 nucleases into highly active enzymes by directed evolution.'
#Preprint #CRISPR

https://www.biorxiv.org/content/10.1101/2023.09.18.558227v1

Vultures and influenza.

"Positive serological status of 2 individuals confirmed that they had been infected by HPAI viruses. Death was recorded for 3 of the 31 tracked individuals, whereas all others recovered and returned quickly to their foraging routine, although at least 9 birds failed breeding."

https://www.cell.com/current-biology/fulltext/S0960-9822(23)01000-X

"It will be five researchers each year who will be supported to establish their own research teams. And so the hope is that this will make a sustainable difference over time because these people will become role models and advocates for better representation"

https://www.bbc.com/news/science-environment-66825633