Thiago Carvalho @cyrilpedia@social.cleverlibre.org

This week's DEE External Seminars welcomes Mike Whitlock (hosted by Jérome Goudet Group) for a talk Challenges and solutions in identifying the genes responsible for local adaptation 🧬 September 27 at 12h15, Biophore Amphitheater or online https://rec.unil.ch/lives/live_80807

Good news. Looking forward to being able to read and vote on the proposed deal. Hope that they now can close an acceptable deal with SAG-AFTRA.

https://www.nytimes.com/live/2023/09/24/business/hollywood-writers-strike-news?unlocked_article_code=LgL_T0mRX5_jVSu6uOLO4wC8wpQEwAnET8k6CKDfTjgSDB4CSgJqLO8M-N6zP6LGTVHIcSF7k1NbuyyuIqJMUHKbiJcV6l57YWJAeqNKSywmlCTjDMJZ70HP7NK1YHdJ8EAztPK-2d-o8uhvRbUHgjuUxfLltDXRbCRTbMpqVwmDCzSrGmd1yQYZqxq9qS6OecJDDtISvTrWgTBQui-Lr-0qAbi25t-8FrNghQzm2b4bp6ObhsHdFo0Zuwz_SayVvAoZ1LXKqE2YGPpgcaARANhat_nNLmC0tl2gBLMX7TO3xUq3irDRM3YFPWP4iLCJObCIUOPurhaibWyop9oXeeZ9BzSI9ybP6icDrlK-mqrnlA&smid=url-share

"Autoantibodies against receptors involved in the autonomous nervous system have been correlated with symptom severity in PCS. Related symptoms may include postural orthostatic tachycardia, chest pain, and inappropriate sinus tachycardia"

#LongCovid #PASC #POTS

https://www.nature.com/articles/s41598-023-42615-y

Is there a scientific illustrator on here who could do a reasonably easy piece of work quite quickly (within the next 2 weeks or so say) for an article I'm writing?
Or can anyone recommend somebody? Ideally Denmark based (for financial simplicity), but elsewhere not impossible...

#ScienceIllustrator #ScientificIllustration #SciCom

"Actually, we will read your thesis" by Neel Krishnaswami https://semantic-domain.blogspot.com/2023/09/actually-we-will-read-your-thesis.html

"whenever I find a paper I don't understand, I start looking for the PhD thesis based on it. Nine times out of ten, the thesis is vastly more understandable: "obvious" lemmas will have explicit proofs, algorithms will have detailed pseudocode, and the right intuitions and perspectives to take about the topic will be spelled out."

Can relate. A colleague of mine, Stefan Pulver, once mentioned to me the "strategic reserve of Michael Bate's lab PhD student theses" as something of wonder – he was a postdoc in that lab. Huge amounts of data not deemed splashy enough for publication but full of details and caveats and protocols for studies of #Drosophila larvae #neuroscience.

While the climate is telling us to move much faster in the fight against global warming, some political leaders want to slow down. The UK🇬🇧 public support #NetZero as an aspiration. But support drops to 16% if transition involves increasing household bills https://www.ft.com/content/b9912ffe-08dd-4653-863c-21885d727d20

Looks like #TPT works for #MDRTB contacts.
#TB #tuberculosis #IDMastodon #infectiousdeseases

Effectiveness and safety of tuberculosis preventive treatment for contacts of multidrug-resistant tuberculosis patients: A systematic review and Meta-analysis - Clinical Microbiology and Infection https://www.clinicalmicrobiologyandinfection.com/article/S1198-743X(23)00477-9/fulltext?dgcid=raven_jbs_aip_email

What happens under checkpoint inhibition in #pancreaticcancer ? Is #immunotherapy having an effect at all? New insights from trial samples shed some light on this aspect... #Oncology @cyrilpedia @gpollara @chfloudas
https://aacrjournals.org/clincancerres/article/doi/10.1158/1078-0432.CCR-23-1444/729202/PD-1-blockade-induces-reactivation-of-non

"We identify that exhausted CD8+ T cells increase ADRB1 expression and that exposure of ADRB1+ T cells to catecholamines suppresses their cytokine production and proliferation. Exhausted CD8+ T cells cluster around sympathetic nerves in an ADRB1-dependent manner."

https://www.nature.com/articles/s41586-023-06568-6

I'd put this particular example just barely ahead of "number of Steve Seagal movies filmed on campus".

'The rankings are particularly reliant on reductive indicators, which are often a very poor proxy for the quality they claim to indicate (Nobel prize-winning alumni as an indicator of teaching quality for example).'

https://blogs.lse.ac.uk/impactofsocialsciences/2022/01/31/a-narrative-cv-for-universities/

Joseph V. Simone, "a visionary physician-scientist & writer of guidelines & maxims, died Jan 21 2021. Three of Joe’s most famous maxims:
1) Institutions don’t love you back
2) Leadership does matter
3) Contrary to the laws of physics in academic institutions, crap flows uphill

TB

"After some years of decline, both cases and fatalities of this poverty-associated disease are on the rise again, especially in low- and middle-income countries."

https://www.nature.com/articles/s41564-023-01477-w