Single cell analysis uncovers striking cellular heterogeneity of lung infiltrating Tregs during eosinophilic vs. neutrophilic allergic airway inflammation https://www.biorxiv.org/content/10.1101/2023.09.23.559152v1?med=mas
Adaptive immunity: from CRISPR to CRIHSP? https://www.biorxiv.org/content/10.1101/2023.09.25.559221v1?med=mas
"A grandmother detained by the Baton Rouge police for mixing two different prescription pills in the same container said officers interrogated and humiliated her in an unmarked “torture warehouse” known as the Brave Cave, according to a lawsuit filed last week."
https://www.nytimes.com/2023/09/24/us/louisiana-police-brave-cave-abuse.html
Now I cant stop singing "more than a spike gene" to the tune of the BeeGees (protein didnt fit the meter).
'We assessed the role of ORF6 during infection using recombinant viruses carrying a deletion or loss-of-function (LoF) mutation in ORF6. ORF6 plays key roles in interferon antagonism and viral pathogenesis by interfering with nuclear import and specifically the translocation of IRF and STAT transcription factors.'
#Covid #Covid19 #SarsCov2 #Interferon #Virology #Immunology #InnateImmunity
https://www.sciencedirect.com/science/article/pii/S1931312823003281
'We are in a time of eroding trust, as people realize that their contributions to a public space may be taken, monetized and potentially used to compete with them. When that erosion is complete, I worry that our digital public spaces might become even more polluted with untrustworthy content.'
https://www.nytimes.com/2023/09/23/opinion/ai-internet-lawsuit.html
'That these three new RSV shots are coming out at once is no coincidence. They succeed where others failed because they all target a specific weak spot in the virus, first identified in 2013.'
https://www.theatlantic.com/health/archive/2023/09/tripledemic-virus-rsv-vaccine/675417/
Hear no evil, pot lit by @hunchbacksociety
#Ceramics #stoneware #pottery #Handmade #Art #stoneware #artgallery #artmastodon
'It might look like a market, but Varoufakis says it’s anything but. Jeff (Bezos, the owner of Amazon) doesn’t produce capital, he argues. He charges rent. Which isn’t capitalism, it’s feudalism. And us? We’re the serfs.'
Ole Christensen Rømer died #OTD in 1644.
He was a Danish astronomer who, in 1676, made the first measurement of the speed of light (to be approximately 220,000 kilometers per second while working at the Royal Observatory in Paris) and discovery that light travels at a finite speed. Rømer also invented the modern thermometer showing the temperature between two fixed points, namely the points at which water respectively boils and freezes. via @wikipedia
Just over 1000 signatures needed to get this bill for the right to clean air considered at the House of Commons - please do sign! https://petition.parliament.uk/petitions/639320
RT (bsky) |
Leiden Early Drug Discovery & Development (LED3) (@led3hub.bsky.social) https://bsky.app/profile/led3hub.bsky.social/post/3ka72pobfcf26
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#proteomics #prot-RT #prot-other
"The dead were victims of what we too often label as “misinformation,” as though these victims succumbed to random junk on the internet. This was not always the case. The unvaccinated were targeted by a well-financed and newly politicized anti-vaccine movement."
https://www.latimes.com/opinion/story/2023-09-22/antiscience-climate-change-covid-vaccines-antivax
'The dead were victims of what we too often label as “misinformation,” as though these victims succumbed to random junk on the internet. This was not always the case. The unvaccinated were targeted by a well-financed and newly politicized anti-vaccine movement.'
https://www.latimes.com/opinion/story/2023-09-22/antiscience-climate-change-covid-vaccines-antivax
Luke Liu & @ScienceDame explore a #PLOSBiology study showing that the SCO, which sits on the roof of the 3rd ventricle, responds to #glucose by secreting signals into the #CSF, decreasing #ependyma-driven CSF movement Paper: https://plos.io/3Rsb8qV Primer: https://plos.io/46kUNbv
"Me, I don't have the talent, or courage, to do stand up comedy. But I know all about crashing and burning. My last lovely, beautiful grant wasn't even discussed. I'm currently awaiting the bad reviews on the next one, while I'm writing yet another one. I work very hard, and no, it doesn't feel fair."
https://journals.biologists.com/jcs/article/136/17/jcs261520/326613/The-system-I
"Herein we examine the heterogeneous cardiac macrophage response following ischemic injury, with a focus on integrating putative contributions of immunometabolism and implications for therapeutically relevant cardiac injury versus cardiac repair."
“Tengo un amigo que decía que todas las películas son como las ruinas de un castillo. Uno piensa en levantar un castillo, lo que estrena son las ruinas. Y esta, aún más”.
To celebrate the beauty of #DevBio and the creativity of developmental biologists, we’ve joined forces with @the_node to set up a virtual art exhibition
We launch today to coincide with the start of #EDBC2023
Some highlights below...
1/n #DevBio_Art
"Melaku Worede was at the heart of efforts to secure Ethiopia’s heritage of crop diversity — and in ensuring that farmers benefited. From 1979 to 1993, he led one of the premier crop gene banks in the world, the Plant Genetic Resources Center in Addis Ababa (now the Ethiopian Biodiversity Institute). It was a time when uniform monocultures of crops such as maize (corn; Zea mays), wheat (Triticum aestivum) and barley (Hordeum vulgare) were being widely planted. Melaku was passionate about saving the diversity of traditional crops before they were lost. The practices that Melaku developed, which he referred to as ‘conservation through use’, are now applied around the world."
(photo credit: Right Livelihood)
I've worked on all of science, from B cells to T cells.
https://fellowsherpa.com