Thiago Carvalho @cyrilpedia@social.cleverlibre.org
I've worked on all of science, from B cells to T cells.
https://fellowsherpa.com
Joined Nov 2022
Thiago Carvalho
boosted
It's insane the way you have to fall asleep reading the absolute worst fucking news from all over the world about apocalyptic scenarios playing out and then just get up the next day and go to work like "how are we doing on our quarterly goals?"
‘Wales, though. It’s not a huge place.’
‘It’s exactly the size it is, isn’t it?’ Shirely said. ‘Reports are always saying something’s “an area the size of Wales”. And that’s exactly the size Wales is.’
This was met with a short silence.
- Joe Country, Mick Herron.
"Miniature etchings
This series of etchings are inspired by the works of Hercules Seghers, Rembrandt and Bruegel the Younger. Some are also loosely inspired by Dutch landscape paintings from the 17th century. The prints are very small, some are roughly the size of a stamp, and are at times watercoloured."
#Prints #Printmaking #Etching #Handmade #art #artgallery #artmastodon
'An immunoprevention strategy for #Alzheimer's disease is required that will integrate the findings from clinical trials with mechanistic insights from preclinical disease models to select promising antibodies, optimize the timing of intervention, identify early biomarkers, and mitigate potential side effects.'
Thiago Carvalho
boosted
Postdoctoral Research Associate, Notterman Lab
Princeton University
See the full job description on jobRxiv: https://jobrxiv.org/job/princeton-university-27778-postdoctoral-research-associate-notterman-lab/?feed_id=61457
#ScienceJobs #hiring #research
Princeton #UnitedStatesUS #PostdoctoralFellow #Researcher
https://jobrxiv.org/job/princeton-university-27778-postdoctoral-research-associate-notterman-lab/?feed_id=61457
"However, knowledge about the properties of kidney hematopoietic cells, and the functionality of kidney in fish immune systems remain to be elucidated. To this end, our present study generated a comprehensive atlas with 59 hematopoietic stem/progenitor cell (HSPC) and immune-cell types from zebrafish kidney via single-cell transcriptome profiling analysis"
#Preprint #zebrafish
Thiago Carvalho
boosted
When the US Government Commissioned 7,497 Watercolor Paintings of Every Known Fruit in the World (1886)
'This is how it is today with German railways. According to its own statistics, this September only 58.4% of Deutsche Bahn’s long-distance trains ran on time. You need only enter a station to know things have gone badly wrong.'
https://www.theguardian.com/world/commentisfree/2023/oct/08/german-train-travel-deutsche-bahn-kafka
Thiago Carvalho
boosted
This is cool and potentially very handy study. Certain host biomarkers can discriminate actual #UTI from asymptomatic bacteriuria.
Needs to be tested prospectively in independent cohorts, but promising as it makes sense: real UTI = actual #inflammation!
#infectiousdiseases #microbiology #medicine
Diagnostic accuracy of urine biomarkers for urinary tract infection in older women: a case-control study https://www.clinicalmicrobiologyandinfection.com/article/S1198-743X(23)00488-3/fulltext?dgcid=raven_jbs_aip_email#%20#IDMastodon
Thiago Carvalho
boosted
"The US library system, once the best in the world, faces death by a thousand cuts
In addition to political censorship and budget cuts, libraries are being undermined by rapacious digital licensing agreements" op-ed by me:
https://www.theguardian.com/commentisfree/2023/oct/09/us-library-system-attack-digital-licensing
"The individual who deserves most credit for its invention, the English clergyman and mathematician William Oughtred (1574-1660), came to believe the slide rule was dangerous since it removed the need for students to learn any underlying mathematical principles. ‘The true way of Art is not by Instruments, but by Demonstration,’ he complained. ‘It is a preposterous course of vulgar Teachers, to beginne with Instruments, and not with the Sciences, and so instead of Artists, to make their Schollers onely doers of tricks, and as it were jugllers.’"
https://www.lrb.co.uk/the-paper/v45/n19/james-vincent/instrumental-tricks
"For nerds like me, the article has an important message about the field of behavioural economics. We’ll get to that. There’s also a broader question. The subscription business model has expanded from traditional products, such as newspapers and gym memberships to software, streaming media, vegetable boxes, shaving kits, makeup, clothes and support for creative types via Patreon or Substack. We should all be asking ourselves, if so many people are paying not to go to the gym, what else are we paying not to do?"
https://www.ft.com/content/b2622d99-4eaf-44f7-bbe2-4b61c716a06b
Thiago Carvalho
boosted
A Racist #Harvard Scientist Commissioned Photos of Enslaved People. One Possible Descendant Wants to Reclaim Their Story.
==
The images are among the oldest known #photographs of enslaved people in America.
Tamara Lanier’s fight to gain control of them shows there is no clear system in place to repatriate remains of captive Africans or objects associated with them.
Thiago Carvalho
boosted
Online Now: APE1-dependent base excision repair of DNA photodimers in human cells https://www.cell.com/molecular-cell/fulltext/S1097-2765(23)00735-9?rss=yes&utm_source=dlvr.it&utm_medium=mastodon
"Despite the high success of the current COVID-19 vaccines, there are several limitations, including their reduced effectiveness against SARS-CoV-2 VoCs, short duration of protection, inability to induce a mucosal immune response to protect the airways, and high cost of production or distribution (11, 12). Therefore, there is an urgent need to develop the next generation of intranasal COVID-19 vaccines which induce durable and broadly protective immunity, both in the airways and systemically."
Thiago Carvalho
boosted
Could better biomaterial sharing improve the scientific community?
@lab_rihn_th & @aharms485 draw on their experiences of sharing #biomaterials to discuss the advantages, challenges, and ways sharing could be more actively promoted and rewarded.
Thiago Carvalho
boosted
Large body size differences across species in Hymenoptera. Here, an example of a small masked bee (~7 mm) next to a minute ant (<3 mm) on a flower of European sea rocket (Cakile maritima). https://www.inaturalist.org/observations/120155371
And these two are both tiny next to a violet carpenter bee (Xylocopa violacea), measuring well over 40 mm in body length! https://www.inaturalist.org/observations/178658335 Similarly dramatic size differences exist within ant castes of the same species.
#iNatualist #Hymenoptera #nativebees #ants #entomology #insects #fossils #DevBio
Thiago Carvalho
boosted
Wondering here out loud whether these vast differences in body size relate, at least metabolically, to the ability of hemimetabolous insects to hatch from the egg as tiny miniature versions of the adult, and then grow by moulting multiple times. I mean they must relate. These incremental steps, hormonally regulated, surely afford opportunities for evolution to meddle and trigger sexual maturation which, in needing to reallocate resources to reproduction, would concomitantly stop body growth. And it's true that smaller insects moult less times, and that moulting renders the animal helpless (and subject to e.g., predation by hornets: see this poor Mediterranean locust, Anacridium aegyptium https://www.inaturalist.org/observations/91574142 ) for tens of minutes if not more.
#iNaturalist #Orthoptera #grasshopers #entomology #insects #DevBio #wasplove #wasps
"Como Cosimo, Calvino burló en cierto sentido la ley de la gravedad. Fue un escritor inatrapable que, parafraseando dos de sus metáforas más conocidas, supo, desde una poética levedad, degollar monstruosas medusas (Seis propuestas para el próximo milenio) y achicar el infierno gracias a la atención y al aprendizaje continuos (Las ciudades invisibles)."
https://elpais.com/babelia/2023-10-07/italo-calvino-el-escritor-que-achico-el-infierno.html
I've worked on all of science, from B cells to T cells.
https://fellowsherpa.com
Joined Nov 2022
