Thiago Carvalho @cyrilpedia@social.cleverlibre.org
I've worked on all of science, from B cells to T cells.
https://fellowsherpa.com
Joined Nov 2022
Thiago Carvalho
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Genome homeostasis defects drive enlarged cells into senescence https://www.cell.com/molecular-cell/fulltext/S1097-2765(23)00855-9?rss=yes&utm_source=dlvr.it&utm_medium=mastodon
Thiago Carvalho
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"Rio de Janeiro, Brazil
People cool off at Leme beach amid a heatwave. Air temperatures surpassed 50C in some places and red warnings were issued across 3,000 cities"
Photograph: Ricardo Moraes/Reuters
Thiago Carvalho
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Argentina has elected an extreme anarcho-capitalist as their next president. He’s fueled by far-right conspiracy theories and a hatred of the left. Plus, he seems to hear voices in his head.
No surprise, Elon Musk is thrilled.
Thiago Carvalho
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🏳️🌈🖖🏽
A great soul has passed. Rosalynn Carter, wife of President Jimmy Carter, passed away today at age 96. A humanitarian through to the end, she was a fierce advocate for mental health issues. She brought grace and kindness to the White House. She was a treasure. She will be missed.
Thiago Carvalho
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The human Toll-like receptor 2 (TLR2) response during pathogenic Leptospira infection https://www.biorxiv.org/content/10.1101/2023.11.16.567338v1?med=mas
Thiago Carvalho
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Ron DeSantis Defends Elon Musk's Character After Antisemitic Post
https://www.thedailybeast.com/ron-desantis-defends-elon-musks-character-after-antisemetic-post
Thiago Carvalho
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Thought-provoking piece from @deevybee on fraud and junk science. Including a proposal for an MSc in Defence Against The Dark Arts to train scientists to spot fraud.
http://deevybee.blogspot.com/2023/11/defence-against-dark-arts-proposal-for.html
Thiago Carvalho
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NBCUniversal suspended advertising on X / Twitter
X CEO Linda Yaccarino was previously the head of NBCUniversal’s advertising
the CEO of this platform could not get her former employer to “stand with” X after Elon Musk voiced approval of an antisemitic conspiracy theory
Thiago Carvalho
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“In the topsy-turvy world of conservative America, only this amoral figure can deliver the moral victory that the antiabortion movement craves. Only a fanatical liar has the credibility to see it through.” My piece in today’s LA Times. https://www.latimes.com/opinion/story/2023-11-19/trump-election-2024-abortion
"When applied to a KRASG12D small molecule inhibitor I observe a wide degree of intracellular levels of the drug, and that proteomic responses largely stratify based on the concentration of drug within each single cell"
"I strongly endorse this piece by @gregggonsalves at The Nation. I've been hitting on some of the same themes here on the blog and elsewhere - that the FDA is becoming too lenient in drug approvals, that advocacy groups are abetting this too often, and that patients are not actually served by allowing them to take drugs that don't work."
https://www.science.org/content/blog-post/getting-accelerated-approval-wrong
"Built in 2000, this seed bank is one of as many as 1,700 worldwide, otherwise known as ‘“doomsday vaults”: facilities intended to safeguard humanity in the event of civilisation’s collapse. It isn’t just about seeds – researchers are preserving everything from DNA to data, and even faeces. Should it all go wrong, these Noah’s Arks could provide the blueprints for our recovery."
"So far, much of the news coverage of Ozempic and similar drugs has focused on whether they work—and what their side effects might be. But the real story will begin when this emergent form of treatment becomes utterly routine, as it almost certainly will. Most people in America, the richest country in the world, are fat. Almost three-quarters of adults older than 20 live with obesity or overweight. And given the popularity of existing weight-loss treatments, we can deduce that most of those people would rather not be fat. The consequences of the Ozempic revolution will be economic and social, as well as medical. The new drugs will transform people’s relationship with eating—and with one another."
Thiago Carvalho
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"This Editorial highlights the findings of a new article in JAMA Cardiology2 that examines the potential for natural language processing (NLP) models to accurately classify heart failure hospitalizations compared with the gold standard for clinical adjudication and places the findings from this study in context of the possibilities for improving clinical trials through AI."
Thiago Carvalho
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Thiago Carvalho
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Check out the latest episode of the #EMBOpodcast.
I spoke with Hsiao-Han Chang, @evogytis.bsky.social & Hedvig Tamman about viruses, hosts, spillovers, public health... & also starting a new lab, the challenges of mobility, mentorship, & Die Hard Dracula.
#Scicomm #Podcast #Virology #Evolution #Immunology #Pandemic #Zoonosis
Thiago Carvalho
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JAMA on physicians who refuse to wear masks.
#COVID https://jamanetwork.com/journals/jama-health-forum/fullarticle/2811897
Thiago Carvalho
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Henry Markram, of spike timing dependent plasticity (STDP) fame and infamous for the Human Brain Project (HBP), just got a US patent for "Constructing and operating an artificial recurrent neural network": https://patents.google.com/patent/US20230019839A1/en
How is that not something thousands of undergrads are doing with PyTorch every week?
The goal, says the patent text, is for <<methods and processes for constructing and operating a recurrent artificial neural network that acts as a “neurosynaptic computer”>> – which seems patentable, but not the overreach that is patenting the construction and operation of an RNN, which is, instead, ludicrous.
Seems likely that the legal office in Markram's research institution did an overreach and got away with it. Good luck enforcing this patent though: Markram did not invent RNNs.
I've worked on all of science, from B cells to T cells.
https://fellowsherpa.com
Joined Nov 2022
