Thiago Carvalho @cyrilpedia@social.cleverlibre.org

"We showed that treatment with an agonist against the tumor necrosis factor (TNF) receptor superfamily member CD40 in combination with a soluble β-glucan (BG), which targets the C-type lectin receptor (CLR) Dectin-1, was sufficient to trigger productive immunosurveillance in ICB-resistant mouse models of pancreatic ductal adenocarcinoma."
#immunology #Immunotherapy #myeloidcells

https://www.science.org/doi/full/10.1126/sciimmunol.adj5097#tab-contributors

Interesting mix:

"She discusses famous nineteenth-century figures such as Rudolf Virchow, the German physician widely credited as the founder of modern pathology, and Elie Metchnikoff, the Russian zoologist who discovered how white blood cells neutralize invading bacteria, as well as less familiar researchers like Ruslan Medzhitov, Gökhan Hotamışlıgil, and Luigi Ferrucci."

https://www.nybooks.com/articles/2023/12/07/gut-instincts-a-silent-fire-shilpa-ravella/

'Hungarian Prime Minister Viktor Orbán has launched a national consultation in which he links further EU aid to Ukraine to Brussels unblocking funds for his own country, at a moment when Kyiv is struggling to secure future support from its western allies.'

https://www.ft.com/content/62286134-7f91-4c9a-a332-a3a7e15b4b88

Portugal & TB

"A médica recorda que o nosso país "tem estatuto de baixa incidência a nível a mundial, mas é o que tem a incidência mais elevada na Europa Ocidental", e esta situação não pode ser esquecida."

https://www.dn.pt/sociedade/tuberculose-ainda-existe-e-portugal-e-o-pais-da-europa-ocidental-com-incidencia-mais-elevada--17372082.html

Fantastic new resource for #microbiology and #protist enthusiasts from @pjkeelinglab

This #PLOSBiology Essay has freely available technical diagrams, thumbnails and an illustrated tree to highlight the diversity of microbial life.

https://plos.io/47r5ev8

Openly available #illustrations as tools to describe #eukaryotic #microbial #diversity

Beautiful and extremely useful #open #resource from Yana Eglit and @pjkeelinglab depicting eukaryotic microbes in exquisite detail.

Aren’t they lovely? Which is your favorite?
@PLOSBiology
#LoveMicrobiology

https://journals.plos.org/plosbiology/article?id=10.1371/journal.pbio.3002395

Research Specialist II- Das Lab

Stanford University

See the full job description on jobRxiv: https://jobrxiv.org/job/research-specialist-ii-das-lab/?feed_id=65968

#ScienceJobs #hiring #research
Stanford #UnitedStatesUS #ResearchTechnician #Researcher #Scientist
https://jobrxiv.org/job/research-specialist-ii-das-lab/?feed_id=65968

Fast alignment of mass spectra in large proteomics datasets, capturing dissimilarities arising from multiple complex modifications of peptides - BMC Bioinformatics https://bmcbioinformatics.biomedcentral.com/articles/10.1186/s12859-023-05555-y

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#proteomics #prot-paper

"Human cells express TRIM5α that restricts HIV-1. HIV-1 M evolved to escape this restriction by binding cyclophilin A (CYPA) to the viral core. Our data indicate that nonpandemic HIV-1s are sensitive to human TRIM5α."
#HIV #immunology #InnateImmunity

https://www.pnas.org/doi/10.1073/pnas.2306374120

'Chaimite no Arco da Rua Augusta, entre as 08h00 e as 09h00.' Photo ALFREDO CUNHA.

https://www.publico.pt/2023/11/19/politica/prepublicacao/25-abril-1974-quintafeira-2070480

Nooooo!

"Stop-motion animation studio Aardman is running out of clay, it has emerged. According to a report in the Daily Telegraph, Aardman has been left with enough animation clay for one more feature film after the manufacturers of its favourite material closed down earlier this year."

https://www.theguardian.com/film/2023/nov/20/wallace-and-gromit-studio-aardman-animations-running-out-of-clay

Andrew and Silas Chandler have a story that is both unique and representative of the complex relationships that existed during the American Civil War era. Andrew was a white Confederate soldier from Mississippi, and Silas was an enslaved African American man owned by Andrew's family.

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Image: https://www.pbs.org/video/history-detectives-wearing-the-confederate-uniform-slave-or-soldier/

There is an iconic photograph of a black man in what resembles a confederate uniform. It suggests that he was a confederate soldier. In reality, he was a slave. This misrepresentation obscures complex and often painful truths of history, replacing them with a simplified and inaccurate account.

To read uninterrupted text: https://open.substack.com/pub/400years/p/will-we-believe-our-lying-eyes?r=1pv9e3&utm_campaign=post&utm_medium=web

Video Blog: https://youtube.com/@400YearsUNLeashed?si=DCP_AUYj-_7PrZWS

Video Blog 2: https://youtube.com/@BlackBiographics?si=kEV7S1ZL70qlLFCK

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Image: Clark Lee, an enslaved black man to a Confederate white officer,

Swedish Unions vs Musk.
Elon’s about to find out what workers rights look like

Despite the truce, people in Gaza will keep dying – this horrifying death toll must never be forgotten | Owen Jones https://www.theguardian.com/commentisfree/2023/nov/22/gaza-children-death-toll-israel-hamas?utm_source=dlvr.it&utm_medium=mastodon

So excited to be teaching my Science Behind Bias in STEM course again this spring! If you want to teach a similar course we share our resources and even a paper we published on how to teach similar courses in any discipline: https://blogs.cornell.edu/moreaulab/science-behind-bias-seminar-course/