Thiago Carvalho @cyrilpedia@social.cleverlibre.org

Senior Bioinformatics Research Scientist

St. Jude Children's Research Hospital

See the full job description on jobRxiv: https://jobrxiv.org/job/senior-bioinformatics-research-scientist-6/?feed_id=68934

#ScienceJobs #hiring #research
https://jobrxiv.org/job/senior-bioinformatics-research-scientist-6/?feed_id=68934

"The highly migratory phenotype is mediated by a paracrine pathway from a group of self-produced inflammatory cytokines that include IL5, TNFα, IFNγ, and IL8. We exploit this finding to “lock-in” a highly migratory phenotype by developing and expressing receptors, which we call velocity receptors"
#Immunology #Immunotherapy #Preprint #CARTcells

https://www.biorxiv.org/content/10.1101/2023.12.13.571595v1

"Despite what previous studies suggest, our results show that the Drosophila centromere effect is robust to changes in centromere number, repetitive DNA content, as well as repetitive DNA function"

https://academic.oup.com/genetics/advance-article/doi/10.1093/genetics/iyad216/7502601?searchresult=1

 https://open.substack.com/pub/chrishedges/p/israels-genocide-betrays-the-holocaust?r=11rw36&utm_medium=ios&utm_campaign=post
A new world is being born. It is a world where the old rules, more often honored in the breach than the observance, no longer matter. It is a world where vast bureaucratic structures and technologically advanced systems carry out in public view vast killing projects. The industrialized nations, weakened, fearful of global chaos, are sending an ominous message to the Global South and anyone who might think of revolt —  we will kill you without restraint. 
One day, we will all be #Palestinians. 
#Gaza #GenocideJoeKnows

For readers across the world, Tom Gauld's end of year statistics on his #reading habits will strike a chord... enjoy

@bookstodon

The wait is finally over. From 2024, USB-C will be the common standard for electronic devices in the EU – and we have already seen the impact!

It means
🔌The same charger for all phones, tablets and cameras
⚡ Harmonised fast-charging technology
🔄Reduced e-waste

One charger to rule them all.

Now, a reality.

Learn more about the #EUCommonCharger here: https://europa.eu/!hwjj3G

#SingleMarket #DigitalEU

Striking new change in packaging in #France

No plastic for fruit and veg!

Some exceptions, but it's still striking to see.
#ClimateChange #plasticfree #plastic #fruit #apple
https://www.france24.com/en/video/20231227-france-to-ban-plastic-packaging-for-fresh-produce

"We studied the adipose tissue transcriptome in men and women with normal glucose tolerance or type 2 diabetes following an acute exercise bout, revealing substantial exercise- and time-dependent changes, with sustained increase in inflammatory genes in type 2 diabetes"
#Immunology #Metabolism

https://www.cell.com/cell-reports-medicine/fulltext/S2666-3791(23)00565-7

"To build a comprehensive hemocyte single-cell atlas of larval hemocytes, we integrated whole transcriptomes of hemocytes both in circulation and in the lymph gland 72, 96, and 120 hours after egg laying"

https://journals.plos.org/plosgenetics/article?id=10.1371/journal.pgen.1011077

"Irreproducible experiments, projects that failed to meet their goals, datasets we collected but never managed to analyze, and freezers full of unusable samples have taught us the hard way lessons that have led to these 10 simple rules for managing laboratory information."

https://journals.plos.org/ploscompbiol/article?id=10.1371/journal.pcbi.1011652

"Among​ the enduring riddles of American exceptionalism is the absence in the political mainstream of an overtly socialist party. Whereas in Europe socialist and social democratic parties emerged to tame the excesses of private enterprise, the much rawer, more carelessly exploitative forms of capitalism found in the United States failed to provoke a political response of a similar character or on anything like the same scale. The paltry 6 per cent of the popular vote won in the 1912 election by Eugene Debs remains the best performance by a Socialist Party presidential candidate."

https://www.lrb.co.uk/the-paper/v46/n01/colin-kidd/antidote-to-marx

Cómo se comunican los animales

Una mancha oscura en el vientre de un ciervo macho, el sonido que emiten las cigüeñas al chocar entre sí las dos partes de su pico o el olor que ciertos animales territoriales liberan en su orina son señales que transmiten un mensaje. Ya sea por supervivencia o para reproducirse, los animales se comunican. Pero, ¿siempre lo hicieron con las mismas estrategias?

http://lasendadeapolo.es/2023/12/29/como-se-comunican-los-animales/