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The plot thickens:

"We found that the efficacy of the NKG2C+ NK cell responses was significantly associated with previous infection with HCMV, which leads to high NKG2C+ NK cell levels, similar to the previously reported result of an HCMV-specific imprint in the NK cell repertoire"

cell.com/cell/fulltext/S0092-8

"In normal times, the United States stands out among advanced democracies for its high levels of poverty and its low levels of aid. In 2019, right before Covid struck, America’s relative child poverty rate resembled that of Mexico or Bulgaria."

nybooks.com/articles/2024/01/1

"One of the strangest and least-studied enigmas, though, is how tattoos survive at all. Our immune system is constantly doing its darndest to destroy them—and understanding why it fails could clue us in to one of our bodies’ most important functions, even when we leave the skin blank."

theatlantic.com/science/archiv

"Despite recent advances in generative models for proteins, we argue that there are three properties that have yet to be realized simultaneously in one system. These are: modelling the joint, all-atom likelihood of sequences and three-dimensional structures of full protein complexes; achieving this with computation that scales sub-quadratically with the size of the protein system; and enabling conditional sampling under diverse design constraints without retraining."

nature.com/articles/s41586-023

Bottle with quadrupeds, glazed stoneware by @hunchbacksociety

@madparreira.bsky.socialhttps://madalenaparreira.com/Hunchbacksociety

Israeli bombardment destroyed over 70% of Gaza homes: Media office | Israel-Palestine conflict News | Al Jazeera
aljazeera.com/news/2023/12/31/

"Experts say the besieged strip is unrecognisable and its bombing is the most destructive in modern history."

#Palestine #Gaza #Israel #ApartheidIsrael #Genocide #EthnicCleansing #Liquidation

"At certain political houses I frequented they still talked as though to run the British Empire were their private business. It gave me a peculiar sensation to hear it discussed, when a general election was in the air, whether Tom should have the Home Office and whether Dick would be satisfied with Ireland."

gutenberg.ca/ebooks/maughamws-

In the fall of 2021, whistleblower Frances Haugen released a massive set of Facebook internal documents to Congress and global news outlets. The documents revealed that Facebook was well aware of the adverse societal impacts of its technology. cacm.acm.org/magazines/2024/1/

The problems with a lack of #socialhousing are pretty clear, but another aspect of concern is the contempt with which some social #landlords treat their tenants and the lack of interest the Housing Ombudsman has in sanctioning those landlords.

What social housing needs is both more building, but also a social shift away from contempt for those who inhabit these homes.

This is just another aspect of the continued divisive role of #classism in British #politics

theguardian.com/society/2023/d

"To illustrate how the animals “molt” — a process in which a crab pulls its body out of its shell so that it can then grow a larger exoskeleton — the museum has a bizarre video of Ned Suesat-Williams, one of its founders, struggling to crawl out of a suit of armor backward, without using his hands."

nytimes.com/2023/12/27/arts/de

BREAKING NEWS

President Milei today officially announced that he has informed BRICS that Argentina has changed its mind and won’t join BRICS on January 1st as planned by the previous government.
#AureFreePress #Ukraine️ #Russia #Putin #EU #NATO #Zelensky #war #news #Argentina

"Inflammasome-mediated caspase-1 activation facilitates innate immune control of Plasmodium in the liver, thereby limiting the incidence and severity of clinical malaria. However, caspase-1 processing occurs incompletely in both mouse and human hepatocytes and precludes the generation of mature IL-1β or IL-18, unlike in other cells. Why this is so or how it impacts Plasmodium control in the liver has remained unknown."

journals.aai.org/jimmunol/arti

Cutting it a bit fine this year, but it's time again for The Spike's review of the year in neuroscience:

medium.com/the-spike/2023-a-re

Enjoy!

Ursula Le Guin on life before Roe vs Wade… From her book of essays Words Are My Matter @bookstodon #feminism #abortion #BeingAWoman

US residents: If you haven't ordered your free COVID tests through USPS in the last five or six weeks, you're eligible for four more per household. It takes about a minute to fill out the online form, and USPS delivers them to your mailbox.

Testing is a great way to keep friends, family, and coworkers safe.

special.usps.com/testkits

"Among countries that have published more than 100,000 articles in the past two decades, Nature’s analysis suggests that Saudi Arabia has the highest retraction rate, of 30 per 10,000 articles, excluding retractions based on conference papers"

nature.com/articles/d41586-023

"Probablemente nada haya contribuido más a mejorar la salud de los seres humanos en los últimos dos siglos que el desarrollo de vacunas fiables y seguras para las enfermedades infecciosas comunes. Por lo tanto, es muy atractivo y casi romántico preguntarse también si podemos utilizar las vacunas como estrategia de prevención o tratamiento del cáncer."

elpais.com/salud-y-bienestar/2

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