Thiago Carvalho @cyrilpedia@social.cleverlibre.org
I've worked on all of science, from B cells to T cells.
https://fellowsherpa.com
Joined Nov 2022
'Impaired mitochondrial transport in the axon is another feature of aging and neurodegenerative diseases. Using Drosophila, we found that genetic depletion of axonal mitochondria causes dysregulation of translation and protein degradation.'
Thiago Carvalho
boosted
'Those customers are both on the author side and the editorial side. You too can be a co-author if you just pony up, and if you're an editor, well, you can earn extra cash by slotting these papers into the journal. An especially good route to that has been the "Special Issue" racket, where a group of themed papers are rounded up by a guest editor'
https://www.science.org/content/blog-post/just-bribe-everyone-it-s-only-scientific-record
Thiago Carvalho
boosted
Arriving at the end of three wonderful weeks hosted by Sidonia & Masaki Tajima at Kyoto's Center for Cancer Immunotherapy & Immunobiology.
More on the center later, but you can browse their site at the link below 👇
Thiago Carvalho
boosted
Clever "dual bubble switch" that uses an aptamer (DNA oligo selected / designed to bind to an analyte) and fluorophore + quencher for optical read-out.
Good for detecting uM dopamine in the brain! Better than cyclic voltammetry & it's lack of specificity.
https://www.biorxiv.org/content/10.1101/2023.03.03.531030v1.full
'Hilariously, Sunak insists anyone failing to get behind all this just wants to take us “back to square one”. Square one? Oh man – who wouldn’t take square one in a heartbeat? We’re somewhere near square minus 39 here, receding backwards through the squares until the place of utter darkness beyond all squares'
https://www.theguardian.com/commentisfree/2024/jan/19/tories-squid-game-rwanda-policy
Thiago Carvalho
boosted
'The evidence is plain to see. A woman dies somewhere in the world every two minutes during pregnancy or childbirth, and each day more than 6,000 neonatal babies die within their first four weeks of life. This unacceptable death toll is especially high in sub-Saharan Africa.'
https://www.ft.com/content/35ce3cff-7579-4784-8af6-16ba7fd54d14
Thiago Carvalho
boosted
Ubiquiton—An inducible, linkage-specific polyubiquitylation tool https://www.cell.com/molecular-cell/fulltext/S1097-2765(23)00961-9?rss=yes&utm_source=dlvr.it&utm_medium=mastodon
'When news of the study broke, Chuck Stone, a journalist and former Tuskegee Airman,responded with an impassioned editorial, writing, “It either takes a tough constitution or a rancid morality to sit quietly by and watch 200 men die without doing anything about it. I call it genocide. Have you got a better name for it?”
Thiago Carvalho
boosted
SHP2-triggered endothelium activation fuels estradiol-independent endometrial sterile inflammation https://www.biorxiv.org/content/10.1101/2024.01.16.575960v1?med=mas
Thiago Carvalho
boosted
🌍 Implementing a hospital sustainability quality improvement project: Challenges and best practice for trainees 🌍
Read more: https://www.bmj.com/content/384/bmj.p2936
Thiago Carvalho
boosted
PhD position “Combined Viro-Immunotherapy"
University Hospital Tuebingen, Werner Siemens Imaging Center, Preclinical Imaging and Radiopharmacy
The WSIC offers a PhD position in the field of “Combined Viro-Immunotherapy and PET/MRI guided monitoring of in vivo immune responses”.
See the full job description o...
https://jobrxiv.org/job/university-hospital-tuebingen-werner-siemens-imaging-center-preclinical-imaging-and-radiopharmacy-27779-phd-position-combined-viro-immunotherapy/?feed_id=70399
Thiago Carvalho
boosted
'The Rhodesian inquiries were conducted under, and influenced by, the conditions and attitudes of British occupation and colonial rule. Nearly all the statements and testimonies of Black witnesses were dismissed or disqualified. In the photographs of the victims, the bodies are labeled according to their nationalities, with the exception of Sergeant Serge Barrau from Haiti; his body is simply labeled as “Coloured.”'
https://yalereview.org/article/susan-williams-dag-hammarskjold-crash-
Thiago Carvalho
boosted
Thiago Carvalho
boosted
Who'da thunk vulture capitalists weren't good at flying? https://brianmcfadden.org/2024/01/12/boeings-blueprints-for-success/
"Like millions of other high-risk people who are service workers, older, chronically ill, disabled, or immunocompromised, I have done everything I can to remain as safe as possible. Due to neuromuscular disability and respiratory failure, my chances of surviving an infection are slim to none. With the latest JN.1 variant likely even more contagious – or better practiced at evading immune system defenses – than previous ones, I wonder if this is the surge when I will become infected, which is terrifying."
https://www.teenvogue.com/story/covid-isnt-going-anywhere-masking-up-could-save-my-life
'Power analysis currently dominates sample size determination for experiments, particularly in grant and ethics applications. Yet, this focus could paradoxically result in suboptimal study design because publication biases towards studies with the largest effects can lead to the overestimation of effect sizes'
https://journals.plos.org/plosbiology/article?id=10.1371/journal.pbio.3002423
Thiago Carvalho
boosted
Found an interesting piece of trivia: Highlander 2 (released 1991, set in 2024 btw) is according to #Wikipedia "one of the worst films ever made". On Rotten Tomatoes it has the "rare approval rating of 0%". Critics consensus was "there should have been only one".
Thiago Carvalho
boosted
Entertainer, childhood literacy advocate, and scientific philanthropist Dolly Parton was born #OTD in 1946.
Mostly known for singing and songwriting, Dolly's Imagination Library program has distributed over 100 million free books to kids around the world.
https://dollyparton.com/imagination-library
Normally I do #OTD posts for scientists and mathematicians, or important discoveries. But Dolly Parton has done as much as any living person to promote childhood literacy so I am proud to include her on the list.
Arriving at the end of three wonderful weeks hosted by Sidonia & Masaki Tajima at Kyoto's Center for Cancer Immunotherapy & Immunobiology.
More on the center later, but you can browse their site at the link below 👇
Thiago Carvalho
boosted
"The scientists described trawling as “marine deforestation” that causes “irreparable harm” to the climate, society and wildlife.
Trawling hotspots in the East China Sea, the Baltic, the North Sea and the Greenland Sea have the largest climate emissions, the study said. Carbon released from the sea floor also causes local acidification, reducing the oceans’ capacity to absorb carbon, the study found."
I've worked on all of science, from B cells to T cells.
https://fellowsherpa.com
Joined Nov 2022
