Thiago Carvalho @cyrilpedia@social.cleverlibre.org
I've worked on all of science, from B cells to T cells.
https://fellowsherpa.com
Joined Nov 2022
'The results indicate parallels between the evolution of Alzheimer’s and CJD, potentially boosting research into diagnostics and therapies to combat all forms of dementia.
The study examined eight people who had received the hormone as children but did not develop CJD. The scientists found that five of these patients showed symptoms consistent with early-onset Alzheimer’s.'
https://www.ft.com/content/745aa1e2-54fb-483b-9527-4c132f9a6aef
Thiago Carvalho
boosted
Open science is key to the mission of #PLOSBiology.
PLOS Open Research Manager Lauren Cadwallader & @npariente reflect on #OpenScience at the journal in this Editorial, discussing why and how we shall continue to hold it central to everything we do.
'I see reviewers regularly mistake complexity, difficulty, and technicality for novelty. In science reviewing, novelty seems to imply these things. We might be better served by removing the word "novelty" from the review instructions and replacing it with beauty.'
'In 2012 researchers modeled the effects that the different atmospheres, pressures, and temperatures on Venus, Mars, and Saturn’s moon Titan would have on the human voice and other sounds. Setting aside the detail that on Venus a human being would be crushed and burned up almost instantaneously, the pitch of your voice would become much deeper as the vocal cords vibrated more slowly in the gassy soup of its atmosphere. However, because the speed of sound is much faster than it is on Earth, our brain would judge the speaker to be farther away. Humans on Venus, the researchers concluded, would sound like bass Smurfs.'
Thiago Carvalho
boosted
It was said that Charlie Chaplin was the only person in Hollywood Albert Einstein wanted to meet. In 1931, he got his chance to talk to the actor at the premiere of the film 'City Lights'.
"What I most admire about your art, is your universality," Einstein said to Chaplin. "You don’t say a word, yet the world understands you!"
"True. But your glory is even greater!" he told the physicist. "The whole world admires you, even though they don’t understand a word of what you say."
via @NobelPrize
Thiago Carvalho
boosted
What did Albert Einstein, James D. Watson, and Max Perutz think about #PeerReview?
Join us for the Lunch & Learn: History of Peer Review session on February 21 to find out (you might be surprised!).
https://us02web.zoom.us/meeting/register/tZMocOGqqzopG9E0EYwLt1nkkL4wzJlJlPzA#/registration
#preprint #research #science #publishing #OpenScience
Thiago Carvalho
boosted
Maria Cunitz (1610 – 22 August 1664) was an Silesian astronomer, and the most notable female astronomer of the early modern era. She authored a book "Urania propitia", in which she provided new tables, new ephemera, and a simpler working solution to Kepler's second law for determining the position of a planet on its elliptical path. The Cunitz crater on Venus is named after her. The minor planet 12624 Mariacunitia is named in her honour. via @wikipedia
Thiago Carvalho
boosted
"Here, we investigated how eosinophils adapt to the small intestine (SI) microenvironment and the local signals that regulate this process. We observed that eosinophils gradually migrate along the crypt–villus axis, giving rise to a villus-resident subpopulation with a distinct transcriptional signature. Retinoic acid signaling was specifically required for maintenance of this subpopulation, while IL-5 was largely dispensable outside of its canonical role in eosinophil production."
#Immunology
Thiago Carvalho
boosted
'This raises intriguing questions: Do plants age? How do they escape the typical trajectory of senescence, and what factors contribute to their remarkable longevity? What limits their lifespan? How are these unique characteristics intertwined with plant life strategies and evolutionary pathways?'
Volkava & Riha @emboreports
https://www.embopress.org/doi/full/10.1038/s44319-024-00062-4
Thiago Carvalho
boosted
"While severe neurodevelopmental disorders (NDDs) caused by penetrant de novo mutations approximate Mendelian models of causality, Mendelian causal logic has been seen as inapplicable to common mental disorders for decades. I sometimes think that it is criminal that Mendel is taught in school without even a whiff of quantitative genetics to balance it."
https://www.psychiatrymargins.com/p/a-note-from-hyman-on-the-genetic
Thiago Carvalho
boosted
Scenes from the meritocracy:
'He started by editing college essays from his Yale dorm room for $50 an hour but now charges the parents of his company’s 190 clients — mostly private-school kids, many of them in New York — $120,000 a year to help them create a narrative he believes will appeal to college-admissions officers. That company, Command Education, currently has 41 full-time staffers, most of whom are recent graduates of top-tier colleges and universities. The pitch is crafted to appeal to the wealthy clients Rim courts: a “personalized, white glove” service, through which Command employees do everything from curating students’ extracurriculars to helping them land summer internships, craft essays, and manage their course loads with the single goal of getting them in.'
Thiago Carvalho
boosted
Have you ever thought “My life is 1:21:32 too long and I'd love to listen to @christlet pontificating on microscopy, neurons and science”? Say no more! https://www.youtube.com/playlist?list=PLikZKI8NN-wmpg5-Mo-6Ph8ikvdPvKKYb
Big thanks to the Göttingen students team for having me!
Thiago Carvalho
boosted
Islands of genomic stability in the face of genetically unstable metastatic cancer https://www.biorxiv.org/content/10.1101/2024.01.26.577508v1?med=mas
Thiago Carvalho
boosted
"While severe neurodevelopmental disorders (NDDs) caused by penetrant de novo mutations approximate Mendelian models of causality, Mendelian causal logic has been seen as inapplicable to common mental disorders for decades. I sometimes think that it is criminal that Mendel is taught in school without even a whiff of quantitative genetics to balance it."
https://www.psychiatrymargins.com/p/a-note-from-hyman-on-the-genetic
Thiago Carvalho
boosted
"La inteligencia artificial es el síntoma, no la causa. Nadie cambia periodistas por modelos de IA para mejorar el producto, sólo para “optimizar” la producción. Esa es la ideología que sedujo a la prensa hace 20 años y que nos ha traído hasta este momento. El día que contrataron su primer optimizador de buscadores (SEO, por sus siglas en inglés), los medios empezaron a trabajar para Google, en lugar de escribir para el lector."
@minipetite en @el_pais https://elpais.com/opinion/2024-01-29/el-apocalipsis-mediatico-tiene-cura-entrenar-periodistas-no-ia.html
Thiago Carvalho
boosted
#Preprints are accelerating scientific discovery, but are our public conversations keeping up?
We compiled 7 tips to help you with your #SciComm and communicate preprinted research effectively and responsibly on social media and beyond! https://elifesciences.org/inside-elife/52a057d0/science-communication-seven-tips-for-discussing-preprints-on-social-media?utm_source=mastodon&utm_medium=social&utm_campaign=organic 13/n
Thiago Carvalho
boosted
#OTD in 1845. "The Raven" is published in The Evening Mirror in New York, the 1st publication with the name of the author, Edgar Allan Poe.
Its publication made Poe popular in his lifetime, although it did not bring him much financial success. The poem was soon reprinted, parodied, & illustrated. Critical opinion is divided as to the poem's literary status, but it nevertheless remains one of the most famous poems ever written.
The Raven by Edgar Allan Poe at PG:
https://www.gutenberg.org/ebooks/17192
I've worked on all of science, from B cells to T cells.
https://fellowsherpa.com
Joined Nov 2022
