Thiago Carvalho @cyrilpedia@social.cleverlibre.org
I've worked on all of science, from B cells to T cells.
https://fellowsherpa.com
Joined Nov 2022
Thiago Carvalho
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Postdoc researchers play a pivotal role in scientific progress but early departures are seen at alarming rates.
#eLifeAmbassador Verena Haage leads an international survey of postdocs to understand their experiences and how they could be helped. Get involved: https://elifesciences.org/inside-elife/015caaa0/elife-ambassadors-survey-why-postdocs-leave-labs?utm_source=twitter&utm_medium=social&utm_campaign=organic
Thiago Carvalho
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Editorial: Research funders must join the fight for equal access to medicines | Nature https://www.nature.com/articles/d41586-024-00237-y
Thiago Carvalho
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Not All Fossil Fuels are Created Equal.
“Fortunately, reducing methane emissions — and, by extension, methane intensity — is dirt cheap. A Dunsky report found that a 75 per cent reduction in upstream oil and gas methane emissions would cost as little as $11 per tonne of carbon dioxide equivalent.”
#Canada #Methane #Alberta #Saskatchewan #FossilFuels #ClimateChange
https://thetyee.ca/Analysis/2024/01/30/Not-All-Fossil-Fuels-Created-Equal/?utm_source=daily&utm_medium=email&utm_campaign=300124
Thiago Carvalho
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Featured post: Even though there's ample evidence that he didn't receive a fair trial, #Texas is set to execute Ivan Cantu over a fatal 2001 double shooting. Staff Writer Michelle Pitcher unpacks this complex case ... https://www.texasobserver.org/ivan-cantu-is-set-to-be-executed-but-did-he-get-a-fair-trial?utm_campaign=mastodon
#DeathPenalty #HumanRights #prison #murder #CriminalJustice #news #politics #USpol #law #TrueCrime
Thiago Carvalho
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How Being Bilingual Helps Your Brain (Even If You Learn a New Language in Adulthood)
https://www.openculture.com/2024/01/how-being-bilingual-helps-your-brain.html
Thiago Carvalho
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Improved Signal Processing for Mass Shifting Ions in Charge Detection Mass Spectrometry https://pubs.acs.org/doi/10.1021/jasms.3c00435
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#proteomics #prot-paper
Thiago Carvalho
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😲
🤔
"As they collect and analyze massive amounts of genetic sequences from plants, animals, and microbes, biologists keep encountering surprises, including some that may challenge the very definition of life. The latest, reported this week in a preprint, is a new kind of viruslike entity that inhabits bacteria dwelling in the human mouth and gut. These “obelisks,” as they’re called by the Stanford University team"
Science | AAAS
https://www.science.org/content/article/it-s-insane-new-viruslike-entities-found-human-gut-microbes
'The predictions from the hydrophobicity hypothesis largely hold true. Genes encoding hydrophobic proteins are constrained to be expressed in mitochondria unless hydrophobicity is naturally or artificially reduced. The hydrophobicity hypothesis fails to explain why relatively hydrophilic proteins are retained in mitogenomes.'
https://bmcbiol.biomedcentral.com/articles/10.1186/s12915-024-01824-1
Thiago Carvalho
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'French leaders made a pledge to enshrine abortion rights in the constitution after the US overturned Roe v Wade in June 2022, recognising that reproductive freedoms are fragile and at the mercy of a change in government. But Macron’s government has, so far, emboldened and legitimised the country’s anti-abortion movement by resorting to fearmongering around declining birthrates (in 2023, France still had the highest fertility rate in the EU), and directly engaging with anti-abortion organisations. Earlier this month, to the dismay of women’s rights campaigners, the health minister paid a visit to a leading anti-abortion organisation.'
"The idea that misfolded beta-amyloid might be a prion-like disease has also been around for a long time, because it makes a lot of sense. Indeed, histopathology of patients who died from transmitted CJD has already shown (in several studies) the presence of aggregated beta-amyloid protein, with the implication that this could have been transmitted as well. There have been also reports for over ten years that injection of human Alzheimer's brain proteins into mice leads to AD-like pathology in mouse brains. In 2018, the same authors of this new paper showed that archived samples of toxic cadaveric growth hormone did indeed contain substantial amounts of soluble beta-amyloid, and that injected thse into mice caused such pathology as well. Putting these and other lines of evidence together, this newest paper fits a puzzle piece right where you'd expect one to go. It shows that some of the growth-hormone-treated patients did indeed go on to develop #Alzheimer's, as feared."
https://www.science.org/content/blog-post/infectious-amyloid-infectious-alzheimer-s
Thiago Carvalho
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“Imagine you’re in a waiting room & someone sits next to you with 4 iPhones strapped to their forehead. You might swiftly relocate. Yet that’s exactly what’s happening when someone straps on Apple’s new Vision Pro headset.. each contains 2 depth sensors, 6 microphones and 12 cameras” https://wapo.st/3un22lX
"More than 207,000 cases were diagnosed in 2022, the last year for which data are available. That represents an 80 percent increase since 2018, and 17 percent over the previous year’s tally, according to a new C.D.C. report." #syphilis
#publichealth #infectiousdisease
https://www.nytimes.com/2024/01/30/health/syphilis-cdc.html?smid=threads-nytimes
Thiago Carvalho
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Coordinated in confined migration: crosstalk between the nucleus and ion channel-mediated mechanosensation https://www.cell.com/trends/cell-biology/fulltext/S0962-8924(24)00001-1?rss=yes&utm_source=dlvr.it&utm_medium=mastodon
Thiago Carvalho
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Developmental noise and phenotypic plasticity are correlated in Drosophila simulans.
https://doi.org/10.1093/evlett/qrad069
Now in @EvolLetters by Keita Saito, Masahito Tsuboi, and Yuma Takahashi.
"I’m excited to announce that we have now opened applications for the second round of Development’s Pathway to Indpendence Programme. This programme is aimed at supporting postdocs who will be going on the job market next year – providing mentorship, training and networking opportunities."
'Miller’s attention turned toward investigating how best to mimic the apoptotic cells, overriding the expression of dendritic cells. He partnered with polymer chemist Lonnie D. Shea, PhD, who was at the McCormick School of Engineering, to develop a nanoparticle that interacts effectively with dendritic cells.'
#Immunology #autoimmunity #autoimmunedisease
Thiago Carvalho
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STAT+: Cour Pharmaceuticals, a biotech taking aim at autoimmune diseases, raises $105 million
'The flurry of retractions and corrections follows a major project in 2021 which found that researchers could reproduce results from only half of the top pre-clinical cancer studies they looked at. In many cases, when the experiments were repeated, any positive outcomes were far smaller than originally claimed. “Maybe part of that is because the work being done isn’t high quality,” David said. “It all eventually filters through to a lack of replicability.”
Thiago Carvalho
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Novel Covalent Probe Selectively Targeting Glutathione Peroxidase 4 In Vivo: Potential Applications in Pancreatic Cancer Therapy https://covalentmodifiers.blogspot.com/2024/01/novel-covalent-probe-selectively.html?utm_source=dlvr.it&utm_medium=mastodon
Thiago Carvalho
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New article! Read AutoTransOP: translating omics signatures without orthologue requirements using deep learning https://www.nature.com/articles/s41540-024-00341-9?utm_source=dlvr.it&utm_medium=mastodon in npj SBA
I've worked on all of science, from B cells to T cells.
https://fellowsherpa.com
Joined Nov 2022
