My latest for The Nation.
The Fight for the Soul of American Medicine
More and more physicians are rejecting the forces of conservatism within their field and joining the grassroots movement to revolutionize American medicine. Featuring Suhas Gondi, Sanjay Kishore, Don Berwick, Eric Reinhart, J. Michael McWilliams. #medicine #publichealth #finance #SDoH
https://www.thenation.com/article/society/doctors-american-medicine-public-health/
"Las leches de fórmula, como muchos otros productos de consumo, utilizan la ciencia para venderse. Algunas de las atribuciones más frecuentes son que benefician el desarrollo del cerebro o del sistema inmunológico del bebé o que favorecen su crecimiento. Sin embargo, según un artículo publicado hoy en la revista BMJ, la mayor parte de esas virtudes saludables que aparecen en los paquetes o en los anuncios de los sustitutos de leche materna tienen escasa o ninguna evidencia científica."
My latest Clinical Pipeline column for #NatureMedicine is out, a look at Moderna's RNA vaccine for RSV & a survey of what's, well, in the pipeline, for RSV immunotherapies, including vaccines and monoclonals.
#Vaccine #drugdiscovery #drugdevelopment #mRNA #RSV #immunology #MonoclonalAntibody
PROTAC degraders Rock! Read this application to the #Polycomb BMI and RING1B proteins:
Targeted Degradation of PRC1 Components, BMI1 and RING1B, via a Novel Protein Complex Degrader Strategy.
https://doi.org/10.1002/advs.202205573
"The area of sea ice around Antarctica has hit a record low, with scientists reporting “never having seen such an extreme situation before”.
https://www.theguardian.com/world/2023/feb/15/antarctic-sea-ice-hits-record-low-climate-crisis?CMP=share_btn_tw
Exciting news: UMass is hiring a new professor for our program and the rank is open for both Assistant and Associate. The link to apply is: https://careers.umass.edu/amherst/en-us/job/517690/assistantassociate-professor-college-of-education-remp
Please share with any outstanding psychometricians you know who may be interested in working in one of the best and most productive measurement programs in the world
#WHO aims to accelerate trials of vaccine candidates for #Marburg disease
https://healthpolicy-watch.news/who-accelerate-vaccine-marburg/
Nonrandomised controlled trial in recurrent glioblastoma patients: the promise of autologous tumour lysate-loaded dendritic cell vaccination
Harvest in Bourgogne (France 1963). Vendemmia in Borgogna (Francia 1963). Photo: Hans Silvester. #BlackAndWhitePhotography
Exciting new paper in @PLOSBiology — we show that plasmids use translational global regulators to rewire host cells including expression of key ecological traits, like metabolism and motility, whilst also boosting horizontal transmission of the plasmid
This was a big collaborative effort with colleagues at John Innes Centre, Birmingham, Sheffield & Liverpool
#plasmid #HGT #MobileGeneticElements
https://journals.plos.org/plosbiology/article?id=10.1371/journal.pbio.3001988
When it gets hot, Polycomb comes to the rescue... "Warm temperature-triggered developmental reprogramming requires VIL1-mediated genome-wide H3K27me3 accumulation in Arabidopsis" https://journals.biologists.com/dev/article-abstract/doi/10.1242/dev.201343/286988/Warm-temperature-triggered-developmental/
'A team of Israeli contractors who claim to have manipulated more than 30 elections around the world using hacking, sabotage and automated disinformation on social media has been exposed in a new investigation.'
"Early studies of iron-binding proteins in insects suggested that insects and mammals have surprisingly different mechanisms of iron homeostasis, including different primary mechanisms for exporting iron from cells and for transporting iron from one cell to another, and subsequent studies have continued to support this view."
https://www.annualreviews.org/doi/abs/10.1146/annurev-ento-040622-092836
After seeing pretty compelling evidence that #musk is forcing you to see his illuminated thoughts either you like it or not (and #Twitter engineers to tweak the system to do so), I am really wondering why is anyone still interested in a platform that so obviously feeds you what *he* wants you to see... #scaryshit
Fine, maybe not *all*
“It would be foolish to blame consultancies for all the problems that advanced capitalism has created,” state Mariana Mazzucato and Rosie Collington in their conclusion. Nevertheless, the authors of The Big Con blame consultancies for an awful lot, starting with: “The pristine PowerPoints, copy-and-pasted formulas for strategy and often ineffective tools that many consultancies employ.”
https://www.ft.com/content/ae2a6f5a-68e9-43a1-b313-1664c91e0287
Amazing work, @VikiLovesFACS. So well deserved.
---
RT @ClareCollege
Viki Male (2004) returned to college to receive the alumna of the year award - set up to recognise individual contributions to society.
During the pandemic, Viki ensured pregnant people could access evidence-based information on the COVID vaccine.
http://bit.ly/3K6GWxG
https://twitter.com/ClareCollege/status/1625547468598394883
Congrats to all the newly elected American Academy of #Microbiology fellows - tagging a few I know are on Mastodon @drdrandrews @jenbiddle @chicaScientifica @florian_krammer https://asm.org/Press-Releases/2023/February/65-Fellows-Elected-into-the-American-Academy-of-Mi?_zs=lekpl&_zl=3BRR2
'Chinese pharmaceutical group CanSino Biologics said demand for its Covid-19 vaccine was “dying down” in China after the abrupt end of the country’s tough zero-Covid policies, underscoring the challenges facing the sector in the largest remaining under-vaccinated market'
https://www.ft.com/content/b201dc98-2187-43de-817a-c9a3d0d981b9
I've worked on all of science, from B cells to T cells.
https://fellowsherpa.com