ICYMI: Read about @Dev_journal new partnership with @WoodlandTrust
For every article published a #nativetree is planted in a UK forest
For every peer review, we support the restoration & preservation of #ancientwoodland
https://journals.biologists.com/dev/article/150/6/dev201715/297131/The-Forest-of-Biologists-for-biologists-for
"More and more scientists are realizing that animals, like people, are individuals: They have distinct tendencies, habits, and life experiences that may affect how they perform in an experiment. That means, some researchers argue, that much published research on animal behavior may be biased."
https://www.theatlantic.com/science/archive/2023/03/animal-behavioral-science-personalities/673432/
We are looking for a new PhD student to study experience-dependent modulation of olfactory circuits in the fly brain. See details here: https://jobs.ice.mpg.de/jobposting/d636c2e9509c23a83ce7fe7a0647182b1e2e4d090
Please spread the word! Thanks!
#drosophila #neuroscience #phdPosition
NEW ARTICLE: Ten Essential Classic International Films You Can Watch for Free on YouTube, Part 1
A curated collection of ten masterpieces of world cinema available for free to watch and study on YouTube.
#film #movies #cinema #internationalcinema #WorldCinema #classicfilm #classicmovies #foreignfilm
From Michael Gale's lab, a small molecule RIG-I agonist
"We have now determined direct binding of KIN1148 to RIG-I to drive expression of IFN regulatory factor 3 and NF-κB target genes, including specific immunomodulatory cytokines and chemokines. Intriguingly, KIN1148 does not lead to ATPase activity or compete with ATP for binding but activates RIG-I to induce antiviral gene expression programs distinct from type I IFN treatment"
'We think of him painting the beautiful: Ginevra de’ Benci, Cecilia Gallerani and Salai glow with glossy hair and good bone structure. Yet alongside his fascination with youth and loveliness Leonardo was obsessed with irregular, diseased and aged faces whose “monstrous” distortions he drew with daunting precision.'
RT @IdoAmitLab
Very impressive work, with potential to deepen our understanding of cell-cell communications.
https://www.biorxiv.org/content/10.1101/2023.03.16.533003v1
'In a study published by the American Cancer Society in March, researchers estimated that in 2023, 153,000 people in the United States would be diagnosed with colorectal cancer. Of those cases, about 13 percent would be among people under 50 — representing a 9 percent increase in cases in this age group since 2020.'
https://www.nytimes.com/2023/03/20/well/colon-colorectal-cancer-symptoms-screening.html
my group is finally real! https://child-health-research.centre.uq.edu.au/research/computational-immunology @qldchildres @YUmmunology @LisaTom106 @tuong_lab
Fundamental physics questions:
"Peanut Butter Stirs an Old Debate: To the T.S.A., What’s a Liquid?"
https://www.nytimes.com/2023/03/20/travel/tsa-peanut-butter-liquid-security.html
RT @wolfgangkhuber
Postdoc position in spatial and single-cell computational biology for precision oncology at EMBL
Contribute your skills in data science, statistics, ML to an application of latest technologies to a large clinical collaboration on exciting new drug class
Mitochondrial damage activates the NLRP10 inflammasome
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RT @IIIBonn
We are super excited to share the newest publication from the Latz Lab @IIIBonn in @NatImmunol 🔥🎉
https://www.nature.com/articles/s41590-023-01451-y
A great collaboration with Franklin Zhong and @FISchmidtLab
Summary below, from twitterless 1st author Tom... 1/n
https://twitter.com/IIIBonn/status/1637848269681205248
In my latest Clinical Pipeline column for Nature Medicine, a look at iPSC therapy for heart failure.
"Heartseed is not the only company currently performing clinical trials with iPSC-derived cardiomyocytes. Help Therapeutics in China is also using an approach with allogeneic iPSC-derived cardiomyocytes, and Göttingen University is running a trial for patients with end- stage heart failure using engineered heart muscle composed of a mixture of iPSC- derived cardiomyocytes and stromal cells."
Job alert:
@EMBOPress is recruiting a scientific editor for The @embojournal
The deadline is tomorrow (Mar 21)
"Colograph
The works presented here are created with alternative materials rather than etched on copper. From squashed paper costumes to packaging and leather book covers, objects are inked with different processes, both intaglio and planographic. Scales vary and are usually life-size." by @madparreira #Prints #Handmade #BookArt
Gerhard Richter, Seascape I (Seestück I), 1969 #museumarchive #museumofmodernart http://www.moma.org/collection/works/101596
Tools
"To complement existing tools of small-molecule-based inhibitors, we present a highly potent, novel catalytically-driven glucocorticoid receptors degrader, KH-103, based on proteolysis-targeting chimera technology."
From Carl June et al
"A fundamental limitation of T cell therapies in solid tumors is loss of inflammatory effector functions, such as cytokine production and proliferation. Here, we target a regulatory axis of T cell inflammatory responses, Regnase-1 and Roquin-1, to enhance antitumor responses in human T cells engineered with two clinical-stage immune receptors."
I've worked on all of science, from B cells to T cells.
https://fellowsherpa.com