Thiago Carvalho @cyrilpedia@social.cleverlibre.org

We hold this truth to be self-evident:

"I think there are already a lot of individual PIs who see preprint peer review as a good thing and organise preprint clubs with their students. They see it as valuable training for students who are going to become scientists, but also for students who are not going to become scientists. But this is not necessarily true for all PIs. So my view is that the institutions ought to do more to make it part of their training programs."

https://prelights.biologists.com/news/prelights-talks-to-richard-sever/

Looking back on a BBC classic

https://www.youtube.com/watch?v=8scpGwbvxvI

"At some point during my PhD, I started thinking about science journalism and publishing and my supervisor encouraged me to explore these areas. Basically, I had to figure out whether I wanted to be a journalist or an editor. So when I finished my PhD, I wrote to tons of journalists."
@richardsever

https://prelights.biologists.com/news/prelights-talks-to-richard-sever/

"But then… as he reaches the end of his analysis, Muller offers a stunning prediction. In essence he says that if you want to really understand the structure of the gene, it will not be done with Drosophila. Instead, he recommends the study of “d’Herelle bodies.” In 1917, the French physician Félix d’Hérelle discovered bacteriophage."

https://academic.oup.com/genetics/advance-article/doi/10.1093/genetics/iyad015/7058543?searchresult=1

Models and their quirks:

"Here Muller was exceptionally lucky, because the somatic pairing of homologous chromosomes along their entire length—readily seen in #Drosophila—is not a general feature of eukaryotes."

https://academic.oup.com/genetics/advance-article/doi/10.1093/genetics/iyad015/7058543?searchresult=1

Some of my favorite cover illustrations by Madalena were not selected by editors - like this one for Ilana Gabanyi & @mucida's 2016 paper "Neuro-immune Interactions Drive Tissue Programming in Intestinal Macrophages"

https://www.cell.com/cell/fulltext/S0092-8674(15)01687-6

https://madalenaparreira.com

Antisense oligos & n=1 cases:

“A lot of clinicians might have a patient with a rare disease and want to help, but don’t have any idea how to approach the FDA. Where do you find a source of oligonucleotide for under $500,000? For a single patient?”

https://www.nature.com/articles/s41587-023-01724-9

"I started to understand why so many great writers are obsessed with the repetition of a consistent work schedule: they are all trying to hit a number of words a day that may or may not contain something interesting in them."

https://www.newyorker.com/news/our-columnists/whats-the-point-of-reading-writing-by-humans

"With growing attention on the remains of people held by museums and universities around the world, we outline ethical considerations that researchers working with human remains in anthropology must bear in mind."

https://www.nature.com/articles/s41559-023-02036-6

Not from Portugal, but somehow still good :)

#WinesOfMastodon