Thiago Carvalho @cyrilpedia@social.cleverlibre.org
I've worked on all of science, from B cells to T cells.
https://fellowsherpa.com
Joined Nov 2022
'Senate Bill 17, sponsored by the chair of the Senate Education Committee, is now before that committee. That bill would shift greater authority to the university boards of trustees, would prohibit the use of diversity statements in faculty hiring, and would abolish the activities of diversity, equity and inclusion administrators.'
https://reason.com/volokh/2023/04/12/state-higher-ed-reform-round-up-texas/
Thiago Carvalho
boosted
Discovery of novel amino acid production traits by evolution of synthetic co-cultures
BMC Microbial Cell Factories from Meike Baumgart @fz_juelich
https://microbialcellfactories.biomedcentral.com/articles/10.1186/s12934-023-02078-2
"We report the largest study yet on the impact of lifelong social stress on healthspan, aging-associated diseases, epigenome, and lifespan in multiple mouse laboratory strains."
#neuroscience #behavior #StressResponse
Thiago Carvalho
boosted
Join us for a webinar to hear from our fantastic speaker, Vanessa Fairhurst!
@NessaFairhurst works to support and empower communities of researchers, particularly those at early stages of their career and historically excluded to conduct socially conscious #preprint peer review.
Thiago Carvalho
boosted
Get a pulse on the latest brain science work in the 🔼 this Friday! Register now:
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RT @DukeBrain
The annual @Triangle_SfN meeting is quickly approached! Mark your calendars for APRIL 21st at the @WashingtonDuke for this year's *free* local neuroscience gathering 🔼🧠
More details 👉 https://www.trianglesfnchapter.org
https://twitter.com/DukeBrain/status/1635264456920793088
Thiago Carvalho
boosted
JITC: "Glucocorticoid activation by HSD11B1 limits T cell-driven interferon signaling and response to PD-1 blockade in melanoma"
In a UPCI GWAS of adj IFN-a for melanoma, our stat sig SNP for RFS involved glucocorticoid signaling as well (unpublished)
https://jitc.bmj.com/content/11/4/e004150
'Susana Barra’s home in a quiet suburb of Santiago, Chile, is only a few miles from the site of the former notorious Simón Bolívar death camp, which was operated by the secret police during the Pinochet dictatorship. Susana was eight years old when her 23-year-old sister, Jenny, was taken there in 1977, never to be seen again.'
https://www.theguardian.com/world/2023/apr/17/chile-families-search-disappeared-pinochet
'É importante frisar que só os professores catedráticos e associados pertencem aos quadros das universidades e que, em conjunto, constituíam, em 2019, apenas 20% do total de professores do ensino universitário'
https://www.dn.pt/opiniao/a-agitacao-no-ensino-superior-e-na-ciencia--16188900.html
Thiago Carvalho
boosted
#Viruses can evade #CRISPR/Cas via #mutations that create mismatches between gRNA & viral DNA. @SchellingMAS @GiangNg12638532 @dsashital show that Cas12a can tolerate some mismatches, but they influence outcomes of further viral evolution #PLOSBiology https://plos.io/413LJ8R
Thiago Carvalho
boosted
On this day in 1994: Roger W Sperry died, won 1981 #NobelPrize for showing the specilisation of the two parts of the brain #ThisDayInBiotech
Thiago Carvalho
boosted
Director of Image Analysis @dentenberg
Come use your machine learning and image analysis skills to help cancer patients by developing diagnostics and therapeutics with physician scientists.
https://jobrxiv.org/job/einstein-college-of-medicine-27778-director-of-image-analysis/?feed_id=42732
#ScienceJobs #job #imaging, #ima...
https://jobrxiv.org/job/einstein-college-of-medicine-27778-director-of-image-analysis/?feed_id=42732
Thiago Carvalho
boosted
Don't miss out on #DevPres later this week, where we will hear from the finalists of Development's Oustanding Paper Prize.
Find out more on @the_node https://thenode.biologists.com/development-presents-outstanding-paper-prize-finalists/development-presents/
Register here: https://us02web.zoom.us/webinar/register/9716740379156/WN_0Neo-njbTQi2atA_vxqX3g
About the Paper Prize: https://journals.biologists.com/dev/article/150/7/dev201810/306247/Development-s-Inaugural-Outstanding-Paper-Prize
Thiago Carvalho
boosted
“The NHS is using a US surveillance tech company owned by a billionaire Trump donor to process hundreds of datasets – some of which are being shared with private sector firms.”
Is this how we want it data to be used?
I don’t remember being she’ asked.
https://www.opendemocracy.net/en/palantir-nhs-covid-datastore-foundry-peter-thiel/
My two cents: this should be the rule and not the exception - and it should not be up to the companies. Data from negative trials must be made available.
"In 2018, a group of drug companies agreed to do something unusual in their normally secretive industry. They decided to share confidential clinical data from six failed trials with each other and a select group of specialists who had been brought together by the Alzheimer’s Association, a lobby group for patients’ rights based in Chicago, Illinois."
'Researchers expect that the extensive molecular and clinical data that they produce will help to uncover more about the mechanisms of Alzheimer’s. “Evidence so far points to tau as the initiator of Alzheimer’s symptoms, disabilities and eventually death,” says Boxer. “But this hypothesis needs to be tested in humans.”
Thiago Carvalho
boosted
A #CRISPR-Cas9-tagging approach to induce #chromosome-specific segmental #aneuploidies: targeted assembly of ectopic #kinetochores at endogenous repeats - a way to recapitulate and study specific disease-associated #missegregation events in human cells
@McClellandLab
https://www.embopress.org/doi/10.15252/embj.2022111587
Thiago Carvalho
boosted
Está online, o N° 6 da #Almanaque
Leia toda a edição de Abril, em http://almanaquemag.com
🎨: Capa de @liaferreira
#almanaquemag
#revistaalmanaque
#almanaquemagazine
#ilustracao #editorial #editorialillustration #cover #illustration #liaferreira
Thiago Carvalho
boosted
Faculty postition for Assitant Professor in Biology of Neoplastic Diseases @ICBM_UChile
Academic position call for Biology of Neoplastic Diseases at the Biomedical Sciences Institute (#ICBM), University of Chile, Faculty of Medicine
"The long-acting interleukin-2 drug failed to hit all three primary endpoints of the 783-patient trial in patients with previously untreated unresectable or metastatic melanoma, namely the objective response rate, progression-free survival and overall survival."
https://www.fiercebiotech.com/special-reports/2022s-top-10-clinical-trial-flops
I've worked on all of science, from B cells to T cells.
https://fellowsherpa.com
Joined Nov 2022
