Thiago Carvalho @cyrilpedia@social.cleverlibre.org

'In any case, it is remarkable that senolysis of a small fraction of senescent osteocytes may account for the robust bone-protective effect, further supporting the importance of osteocytes for bone metabolism and skeletal health. Given their crucial role in orchestrating bone remodeling and their high degree of connection, these few senescent osteocytes may be sufficient to cause functional chaos through cellular miscommunication.'

https://www.jci.org/articles/view/169069

"To capture the complex interplay between the tumor antigenic landscape and anti-tumor immunity in lung cancer, we integrated genomics, transcriptomics, immunopeptidomics, spatial transcriptomics and multiplexed immunofluorescence (mIF) imaging to investigate the antigenic landscape in tumors with variable degrees of immune infiltration"
#Immunology #immunooncology

https://www.nature.com/articles/s43018-023-00548-5

Interested in a 𝘀𝗰𝗶𝗲𝗻𝘁𝗶𝗳𝗶𝗰 𝘁𝗿𝗮𝗶𝗻𝗲𝗲𝘀𝗵𝗶𝗽 in a stimulating, multicultural & multi-disciplinary research environment? 👩🏻‍🏫🧑🏽‍💻👨🏼‍💼 👩🏿‍🔬

Applications are open for our scientific traineeship!

𝙅𝙊𝙄𝙉 𝙐𝙎!
👇
https://europa.eu/!R76dyc

#EUcareers

🐦🔗: https://n.respublicae.eu/EU_ScienceHub/status/1654062548868636672

Termination of STING responses is mediated via #ESCRT- and #ubiquitin-dependent degradation to prevent unwarranted #inflammation
Katherine Balka, Dominic De Nardo et al @monashuni
https://www.embopress.org/doi/10.15252/embj.2022112712

Group Leader (m/f/x) - Fibrosis and Wound Healing @BioMed_X

The BioMed X Institute is establishing a new, fully funded research group at its new XSeed Labs incubator.

https://jobrxiv.org/job/biomed-x-institute-27778-group-leader-m-f-x-fibrosis-and-wound-healing/?feed_id=44466

#ScienceJobs #job
Ridgefield, CT #UnitedStatesUS #Grou...
https://jobrxiv.org/job/biomed-x-institute-27778-group-leader-m-f-x-fibrosis-and-wound-healing/?feed_id=44466

Mogarraz, Salamanca.

A change of scene. From the film sets near Almeria, we go to this beautiful town of Mogarraz, where the buildings have faces - literally!

Camera: Mamiya M645 1000S
Film: Ilford FP4
Developer: Ilfotec LC-29 1+19 - 7.5 minutes
.

GPS location: http://www.google.com/maps/place/40.492230,-6.053712

#photography #believeinfilm #filmphotography #analogphotography #filmisnotdead #blackandwhite #bnw #blackandwhitephotography #monochrome #spain #mogarraz

Biology Open helps researchers promote themselves alongside their papers through our #FirstPerson interview series... This week we showcased Rajeshwari B. R. the first author on ‘ Kinetics of Arf1 inactivation regulates Golgi organization and function in non-adherent fibroblasts’.

https://journals.biologists.com/bio/article/12/4/bio059944/308159/First-person-Rajeshwari-B-R

eLife

Metabolic activity organizes olfactory representations https://doi.org/10.7554/eLife.82502

New article! Read Microfluidic cell squeeze-based vaccine comes into clinical investigation https://www.nature.com/articles/s41541-023-00641-x?utm_source=dlvr.it&utm_medium=mastodon in npj Vaccines

Pictures Considered #59: Inside a Choanoflagellate

by Roberto
Choanoflagellates (endearingly referred to as "choanos") are the closest living relative of animals and as such they can provide insights into the evolution of animal multicellularity. Interestingly, at least two choano developmental features are induced by bacterial products.

Read more → https://schaechter.asmblog.org/schaechter/2023/05/by-roberto-fig-1-cut-away-view-through-the-center-of-a-70-cell-b-monosierra-choanoflagellate-rosette-3d-reconstruction.html

#microbiology #choanos

"#preprints really are communicating the most important parts of the #science as soon as they're ready" says Mark Hanson @MarkHanson, first author of the preprint awarded in the ‘Make your negative result a preprint winner’ competition.

Learn more about the competition, Mark's preprint and the value of the publishing negative results in the blog post https://asapbio.org/sharing-negative-results-via-a-preprint-a-conversation-with-mark-hanson

#OpenScience

Today was a big day for the lab: we submitted our first real paper!!! 🥳 It's hard to believe we're here and I'm so excited and proud of us.

But this isn't a thread about the paper.
I want to share (esp with my senior colleagues) what it took for us to get from 2020 to here. 1/

@BiologyOpen
and our publisher
@Co_Biologists
offer a number of practical ways to help you meet the unique needs and challenges you may encounter as an #early-careerresearcher (ECR). Visit our dedicated ECR webpage to find out more: https://www.biologists.com/about-us/early-career/?utm_campaign=BiOSnippet
#Research #sciencemastodon #Scicomms

'A single dose of the human papillomavirus vaccine is highly effective at preventing infections over three years, most likely lowering rates of cervical cancer and other diseases linked to the virus, according to a new study in Kenya.'

https://www.nytimes.com/2023/05/02/health/hpv-vaccine-dose.html?action=click&module=Well&pgtype=Homepage&section=Health

"Personalized genome sequencing has revealed millions of genetic differences between individuals, but our understanding of their clinical relevance remains largely incomplete. To systematically decipher the effects of human genetic variants, we obtained whole genome sequencing data for 809 individuals from 233 primate species, and identified 4.3 million common protein-altering variants with orthologs in human."
#Preprint #Genomics #GeneticVariaton

https://www.biorxiv.org/content/10.1101/2023.05.01.538953v2

The Invisible Cities is a book everyone should read.

"No matter how fantastical those places are in Invisible Cities, he reveals that they’re all Venice. They’re all basically Marco Polo riffing about Venice. It’s his childhood home. Calvino touches on the idea of nostalgia, and I think in the ancient Greek sense of nostalgia—in trying to get home, you go off and you have these adventures"

https://lithub.com/darran-anderson-on-the-ever-shifting-magic-of-italo-calvinos-invisible-cities/