Thiago Carvalho @cyrilpedia@social.cleverlibre.org

Very important for the field of #connectomics is the measurement of stereotypy in neuronal number and morphology within identified cell types–most neurons in the #Drosophila brain are uniquely identifiable and stereotyped.

The stereotypy is very strong across brains – these are excellent news for experimental robustness, i.e., mapping circuits in one brain and performing behavioral and functional experiments in many others.

#neuroscience #DevBiol #Drosophila

"Systematic annotation of a complete adult male Drosophila nerve cord connectome reveals principles of functional organisation", by Marin et al. 2023 (Greg Jefferis lab at #MRCLMB in collaboration with #HHMIJanelia and others).

https://www.biorxiv.org/content/10.1101/2023.06.05.543407v1

On the analysis of the #Drosophila male adult nerve cord (#MANC), reconstructed from #VolumeEM by Takemura et al. 2023 (preprint still pending to come out).

#neuroscience #connectomics

Oh this is pretty!

87 #visualization of the #PeriodicTable of the elements. Now we settled on one, but initially all sorts of design existed-

See them all (as individual images..) https://digital.sciencehistory.org/collections/6w924c45h?f%5Bformat_facet%5D%5B%5D=Image

Excellent from @chrischirp highlighting the need to address inequalities as well as support the nhs for a healthy population Health Care Isn’t the Key to a Healthy Population | WIRED UK

https://www.wired.co.uk/article/christina-pagel-uk-nhs-social-prescriptions-health-care

Postdoc: data-driven modeling of signaling dynamics and fate determinatio

Chan-Zuckerberg Biohub; Stanford university

See the full job description on jobRxiv: https://jobrxiv.org/job/chan-zuckerberg-biohub-stanford-university-27778-postdoc-data-driven-modeling-of-signaling-dynamics-and-fate-determinatio/?feed_id=48691

#ScienceJo...
https://jobrxiv.org/job/chan-zuckerberg-biohub-stanford-university-27778-postdoc-data-driven-modeling-of-signaling-dynamics-and-fate-determinatio/?feed_id=48691

Interested in how #citizenscience can be integrated in universities? On Monday July 3, The European Citizen Science project is organizing an online learning and networking event on the role of #citizenscience in transforming universities. Info and registration:
https://www.eventbrite.com/e/ecs-cluster-event-2023-tickets-640479891597

This Saturday. If you're in Lisbon. After 1am, @RoterdaoC Cais do Sodré, pink street. #disco #funk #house #synthwave #indie #techno

Referenced link: https://www.economist.com/ssa-pod
Discuss on https://discu.eu/q/https://www.economist.com/ssa-pod

Originally posted by The Economist / @TheEconomist: http://nitter.platypush.tech/TheEconomist/status/1674157492203388929#m

Our podcast on science and technology. This week, we meet the scientists studying same-sex attraction in people and explore why this research matters https://www.economist.com/ssa-pod

Last two days to check out "Oubliette", a collective show by
@anaanajottajotta @consta_arouca @jorgenesbitt @madparreira at Biblioteca Camoes, Lisbon.
#Art #exhibition #artgallery
#sculpture #printmaking and more.

"There’s an old adage that to write a good novel, you should write a complete draft, put it in a drawer, then forget about it and start work on what will become the real book. Nonfiction is similar. Writing takes a huge amount of practice, which means it’s a good idea to first build up a portfolio of articles, stories, and blog posts."

https://www.linkedin.com/pulse/how-get-book-deal-sciencetech-write-adam-kucharski%3FtrackingId=ec2bbaayRbQ2wrDY8S9jVg%253D%253D/?trackingId=ec2bbaayRbQ2wrDY8S9jVg%3D%3D

Warm-blooded mega sharks

"To address these uncertainties, we present unique geochemical evidence for thermoregulation in O. megalodon from both clumped isotope paleothermometry and phosphate oxygen isotopes. Our results show that O. megalodon had an overall warmer body temperature compared with its ambient environment and other coexisting shark species, providing quantitative and experimental support for recent biophysical modeling studies that suggest endothermy was one of the key drivers for gigantism in O. megalodon and other lamniform sharks."

https://www.pnas.org/doi/10.1073/pnas.2218153120

The spandrels essay always resurfaces

'A germline-encoded specificity might have arisen as an evolutionary spandrel, a byproduct of immunoglobulin gene diversification in vertebrates, and then been selected (Gould and Lewontin, 1979; Sangesland and Lingwood, 2021; Pennell et al., 2023). For instance, germline alleles with innately high affinity for bacterial antigens might be favored if they protect against commonly encountered pathogens and commensals via broad classes of epitopes shared by these organisms (Yeung et al., 2016; Collins and Jackson, 2018; Sangesland et al., 2020).'

https://www.biorxiv.org/content/10.1101/2022.09.16.508315v4

When life gives you lemons, make some of the funniest material ever caught on film.

"Harold (Ramis) embraced the cheapness of SCTV. Eugene (Levy), Catherine (O'Hara) and I were always moaning about how bad the sets looked and how shitty the props were. Harold would just chuckle and go, “That’s part of the charm!”"

https://torontolife.com/culture/untold-stories-from-the-early-years-of-second-city-the-group-that-changed-comedy/

Meta, YouTube, and Twitter are enabling agitators to subvert democracy (again)

Social media platforms are backsliding, paving the way for chaos in 2024 | Media Matters for America https://www.mediamatters.org/facebook/social-media-platforms-are-backsliding-paving-way-chaos-2024-0

"In this Review, we will discuss how CD8+ T cell developmental trajectories converge with tissue biology, and how factors such as migration to, localization within and the ability to sense different types of microenvironments shape T cell responses."

#Immunology #immunotherapy #immunooncology

https://www.nature.com/articles/s41577-023-00884-8

I love Current Biology - probably my favorite journal ever since I haunted the university library waiting for each new issue to read Sidney Brenner's Loose Ends. But maybe "Free Vaginas" is not the best layout option for their webpage.