"Nobel announcement disagreements often focus on whether the recipients deserved it, or not. But the 2023 Medicine and Physiology prize has received near universal applause: the science that it rewards has already saved the lives of many millions, and (maybe most importantly) has transformed how we think about emerging infectious diseases and other diseases. But the real intrigue surrounds its backstory. Karikó was forced to retire from her position at the University of Pennsylvania in 2013. The much-discussed reasons are familiar villains: the inability to secure major grant funding from the large agencies, and other markers of success in the biomedicine machine."
@cyrilpedia i was actually just reading this. I thought the finale was poignant and correct...
"And while on a good day we can kid ourselves that it doesn’t truly matter … on the bad days, when the chips are down, it really, really does."
One can largely insulate oneself from the chaos on Twitter / X, but sadly supporting it in its current state has negative consequences.
'The country has managed to build itself the longest high-speed rail network in Europe and the second longest in the world, now spanning approximately 2,500 miles (4,000km) (and still expanding). By way of comparison, France has built 1,740 miles (2,800km), and Britain – still coming to terms with its latest high-speed fiasco – 68 (110km).'
Contagious cancer in bivalves
"BTN is a fatal leukemia-like cancer characterized by high numbers of cancer cells in the circulatory fluid of the bivalve and dissemination into tissues in the later stages of disease. BTN cells can survive for days to weeks in seawater17,18 and likely spread from animal to animal by transmission through the water column."
The EU has issued an urgent warning to Elon Musk, giving him 24 hours to respond.
Guardian: EU warns Elon Musk over ‘disinformation’ on X about Hamas attack >>> https://www.google.com/amp/s/amp.theguardian.com/technology/2023/oct/10/eu-warns-elon-musk-over-disinformation-about-hamas-attack-on-x
"Let me remind you that the Digital Services Act sets very precise obligations regarding content moderation..."
"Failing to moderate content such as fake news could incur fine of 6% of X revenues or EU blackout under new laws"
"Desde hace tiempo, las principales zonas de cultivo europeas han visto reducir tanto sus cosechas como la calidad del lúpulo por culpa del trastorno climático. Proyectado hacia el futuro, el trabajo señala a las plantaciones de España y otros países del sur de Europa como las más afectadas por el calentamiento."
'Here’s what infectious disease experts want you to know about some of the most common adult and pediatric viruses (and one bacterial infection): their symptoms, how they spread, how to treat them and when you (or your child) can re-enter society.'
https://www.nytimes.com/interactive/2023/10/06/well/live/contagious-cold-flu-virus-illness.html
Column in The Guardian about high speed rail in Spain https://www.theguardian.com/commentisfree/2023/oct/11/spains-high-speed-trains-arent-just-efficient-they-have-transformed-peoples-lives?CMP=Share_iOSApp_Other
The penultimate paragraph is the crucial one - the network works if you’re going between cities. It doesn’t if you’re going to smaller places or don’t want to go via Madrid.
Very nice review on amphioxus biology https://elifesciences.org/articles/87028 #amphioxus #EvoDevo
"Roswell Park Comprehensive Cancer Center is now requiring masks in its hospital and outpatient clinical areas due to increasing Covid-19 infection rates and in anticipation of cold and flu season."
State data show that positive tests and hospitalizations have been ticking up – a “COVID creep,”
"COVID creep"🤦♂️
"For more than a decade, Twitter was an absolutely key resource for understanding major world events and disasters in real time. Open-source reporters and investigators pieced together the picture on the ground from primary sources and verified content. I’m calling it Twitter in this instance, because that was then. X is something different, although I’m sure we’re all on tenterhooks for its vaunted transformation into the everything app/surveillance capitalism dreamscape humanity deserves."
“His behaviour on the platform — he sets the tone from the top — he’s saying it’s OK to spread conspiracy theories as he does it himself,” said Kayla Gogarty, research director at left-leaning non-profit Media Matters. “This is the first big test for Musk’s version of X. The platform has failed this test.”
https://www.ft.com/content/ca3e08ee-3167-464a-a1d3-677a59387c71?sharetype=blocked
Group Leader position at the #MRCLMB in #connectomics: join us!
https://mrc.tal.net/vx/lang-en-GB/appcentre-1/candidate/postings/2485
Apply by November 16th, 2023.
Areas of particular interest include developing and applying high-density image acquisition methods (electron, X-ray, light) to determine the structure, connectivity and function of intact nervous systems at synaptic resolution; bringing brain-scale connectomics to additional species (including vertebrates); experimental approaches that leverage connectomes to understand brain function; and computational analyses essential for research across these areas.
Excellent piece from summarising findings from the #COVIDVoices report on the detrimental impacts of shielding and the need for involvement of clinically vulnerable people in pandemic planning and readiness https://blog.policy.manchester.ac.uk/posts/2023/10/out-of-mind-what-policymakers-should-learn-from-those-who-shielded-from-covid-19/
'These publicly accessible databases aim to provide an overview of all animal studies (including those that are ongoing and work that may remain unpublished) to increase transparency and reduce unnecessary duplication of experiments. Unfortunately, usage to date has been low, with only a few hundred entries across each registry [7]. As a potential solution, we propose integrating preclinical registration within the animal use protocol (AUP) review process'
https://journals.plos.org/plosbiology/article?id=10.1371/journal.pbio.3002293
"Nobel announcement disagreements often focus on whether the recipients deserved it, or not. But the 2023 Medicine and Physiology prize has received near universal applause: the science that it rewards has already saved the lives of many millions, and (maybe most importantly) has transformed how we think about emerging infectious diseases and other diseases. But the real intrigue surrounds its backstory. Karikó was forced to retire from her position at the University of Pennsylvania in 2013. The much-discussed reasons are familiar villains: the inability to secure major grant funding from the large agencies, and other markers of success in the biomedicine machine."
North Carolina is creating a secret police force
The Joint Legislative Committee on Government Operations, or “Gov Ops” or “ gestapo” is chaired by Republican Senate Leader Phil Berger
It gives the state authority to investigate “possible instances of misfeasance, malfeasance, nonfeasance, mismanagement, waste, abuse, or illegal conduct.”
In a related story: white sheets are sold out at the local Walmart
https://www.documentcloud.org/documents/23986976-2023-appropriations-act-final
Does #CRISPR hold an answer to protecting poultry — and the people who work with poultry — from #birdflu viruses? @STAT's Drew Joseph explores. https://www.statnews.com/2023/10/10/to-protect-chickens-from-bird-flu-researchers-try-to-crispr-in-immunity/
What happened behind the scenes of the LMU Open Research Hybrid Summer School 2023? How was the programme put together, what didactic strategies were used to suit the hybrid format, etc?
Read my advice for future events in the ZBW Open Science Magazine: https://open-science-future.zbw.eu/en/didactics-meets-openness/
I've worked on all of science, from B cells to T cells.
https://fellowsherpa.com