Thiago Carvalho @cyrilpedia@social.cleverlibre.org
I've worked on all of science, from B cells to T cells.
https://fellowsherpa.com
Joined Nov 2022
Thiago Carvalho
boosted
Advancements in kidney organoids and tubuloids to study (dys)function https://www.cell.com/trends/cell-biology/fulltext/S0962-8924(23)00197-6?rss=yes&utm_source=dlvr.it&utm_medium=mastodon
Thiago Carvalho
boosted
On this day in 1942: Christiane Nusslein-Volhard born, won 1995 #NobelPrize http://whatisbiotechnology.org/index.php/people/summary/Nusslein-Volhard
"The people in power are still doubling down on everything that brought us here. They are still outsourcing the pandemic response to the rapacious private healthcare industry. They are still implying that the Covid dead have only themselves to blame—after all, “we have the tools.” They are still insisting that the fault must not be in our stars but in ourselves, transforming an issue of public health into one of personal responsibility."
https://www.thenation.com/article/society/covid-healthcare-policies-permanent/
Thiago Carvalho
boosted
How does exposure to non-mutagenic environmental factors during development contribute to cancer risk? #scRNAseq & spatial transcriptomics reveal how #EndocrineDisruption of #endometrial cell differentiation by #diethylstilbestrol alters the characteristics of stem & progenitor cells, leading to #cancer development. @WilliamsRepro #PLOSBiology https://plos.io/3QpjazO
Thiago Carvalho
boosted
'Dr. Marc Sala, co-director of the Northwestern Medicine Comprehensive Covid-19 Center, said fatigue has become the dominant complaint from his patients. That could be because Covid symptoms are becoming milder overall — he no longer regularly sees patients with severe respiratory damage, and so fatigue has come to the forefront, he said. It’s also possible that fatigue could be a more common symptom with the newer variants, he said.'
https://www.nytimes.com/2023/09/27/well/live/covid-symptoms-fatigue.html
Thiago Carvalho
boosted
"El nuevo subtipo de virus de la gripe aviar está por todas partes. El equipo de Dhanasekaran ha investigado la evolución del patógeno y alerta este miércoles de que “el epicentro” de la crisis se ha desplazado desde Asia hacia Europa y África."
Thiago Carvalho
boosted
@DrALJONES The Balfour Declaration of 1917 was a disaster, as was the Anglo-French Sykes-Picot Agreement of 1916 (https://www.aljazeera.com/features/2018/11/2/more-than-a-century-on-the-balfour-declaration-explained; https://www.britannica.com/event/Balfour-Declaration; https://en.wikipedia.org/wiki/Sykes%E2%80%93Picot_Agreement). The legacy of our colonialism is truly appalling!
People do not want to engage with logos.
"We have found that readers generally do not engage with content posted on the journal handles and we have had limited success with trying things like threads and tagging thought leaders. Where the engagement with journals content happens is with organic posting — an author or collaborator or thought leader will decide to post a journal article, summarize, and offer an opinion. These posts tend to enjoy a significant amount of engagement."
https://scholarlykitchen.sspnet.org/2023/10/19/worth-the-time-critical-look-at-value-of-twitter/
Thiago Carvalho
boosted
Completing genome replication outside of S phase https://www.cell.com/molecular-cell/fulltext/S1097-2765(23)00659-7?rss=yes&utm_source=dlvr.it&utm_medium=mastodon
The effects of the CTLA4 deletion were not very surprising, what's fascinating here is how it compares to the double mutants (PD1/CTLA4).
"CTLA4 disrupted CART19 cells display prolonged surface CAR expression, increased proliferation, and enhanced CART19 effector function supported by unopposed CD28 co-stimulation, which is lost in CART19 cells deficient for both PD-1 and CTLA4"
#Immunology #Immunotherapy #CheckpointInhibitor #CTLA4 #CARTcells
https://www.cell.com/immunity/fulltext/S1074-7613(23)00407-7#secsectitle0075
Thiago Carvalho
boosted
Bacterial histones unveiled
Thiago Carvalho
boosted
Thiago Carvalho
boosted
PhD position - Cardiovascular Immunology
LMU Munich, Dept. of Cardiology
See the full job description on jobRxiv: https://jobrxiv.org/job/lmu-munich-dept-of-cardiology-27778-phd-position-cardiovascular-immunology/?feed_id=62775
#ScienceJobs #hiring #research
Munich #Germany #PhDStudent
https://jobrxiv.org/job/lmu-munich-dept-of-cardiology-27778-phd-position-cardiovascular-immunology/?feed_id=62775
Thiago Carvalho
boosted
Etching on copper, by @madparreira
#Prints #Print #printmaking #copper #printmakingart #printmaker #etching #artgallery #art #artmastodon
"Future outbreaks are inevitable. How do we ensure that research systems are in place and work when we next need them? In 2022, when the global outbreak of mpox emerged, clinical trialists had new tools for rapid rollout of trials; however, the system failed another stress test. In this Viewpoint, we highlight areas for improving implementation of future epidemic clinical trials"
Thiago Carvalho
boosted
"In this review, we discuss key advances that highlight mechanisms used by T cell subsets to populate the epidermis and dermis, maintain skin homeostasis, and regulate wound repair."
Thiago Carvalho
boosted
'Before it released the A.I. chatbot ChatGPT last year, the San Francisco start-up OpenAI added digital guardrails meant to prevent its system from doing things like generating hate speech and disinformation. Google did something similar with its Bard chatbot.
Now a paper from researchers at Princeton, Virginia Tech, Stanford and IBM says those guardrails aren’t as sturdy as A.I. developers seem to believe.'
https://www.nytimes.com/2023/10/19/technology/guardrails-artificial-intelligence-open-source.html
Thiago Carvalho
boosted
What might #OpenScience look like in the future?
By examining past initiatives, this #PLOSBiology Essay offers recommendations to funders, institutions, journals, and stakeholders to create an environment conducive to open science.
"Oito funcionários doutorados da Fundação para a Ciência e a Tecnologia (FCT) assinam uma carta enviada a esta instituição em que reclamam salários iguais aos trabalhadores com contratos a prazo e que têm as mesmas funções. Em causa está a “discriminação subjectiva” na principal instituição que financia a ciência em Portugal: as diferenças salariais rondam, no mínimo, cerca de 500 euros, reclamam."
I've worked on all of science, from B cells to T cells.
https://fellowsherpa.com
Joined Nov 2022
