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"This review highlights recent advances in our understanding of how particulate adjuvants, especially polymer-based particulates, modulate immune responses and how this can be used as a guide for improved adjuvant design."

onlinelibrary.wiley.com/doi/ab

"Esta história faz parte de uma lógica que ajudou a alimentar a utilização em massa do carro, com um novo máximo nos Censos de 2021, tendo triplicado em relação a 1991. Isso aconteceu à custa do transporte público e do andar a pé e é a tendência inversa ao que deve acontecer, quando as metas estão hoje viradas para a redução de emissões de gases com efeito de estufa."

publico.pt/2023/12/01/local/re

Herd immunity by infection, lack of support for isolation, lack of ppe for frontline workers, toxic culture, flip flopping decision making, hairdryers up noses, bleach, aerosol transmission ignored until late… some of things this man will try to defend next week theguardian.com/uk-news/2023/d

At MASP (São Paulo).

"If this sprawling exhibition of 170 artists is an attempt to correct that, bringing Indigenous production into the canon, then it is certainly ambitious in its geographical spread."

ft.com/content/ac6f9f47-cc22-4

Please share these 10 warning signs of possible #Alzheimers disease. Share concerns about your own cognitive #health or that of a loved one with the doctor and ask for a cognitive assessment (which is free as part of the #Medicare Annual #Wellness Visit).

#dementia #aging

“This release . . . is the culmination of 20 years of work and it’s the largest ever release of whole genome sequences in history,” said Cheryl Moore, chief research programmes officer at the Wellcome Trust. “Scientific data that is openly shared allows everyone to contribute groundbreaking discoveries.”

ft.com/content/adb936b9-45b0-4

@cyrilpedia justo unos días después de su fallecimiento, Eulalia Pérez Sedeño escribió una sentida nota recordándola

theconversation.com/evelyn-fox

casualmente llevo unos meses releyendo sus trabajos de los 90-2000 sobre genética

una gran pérdida para los SSS&T

Conversations about what Trump might do if reelected often ignore that he did or tried to do those things first time around. He'd just be less fettered.

washingtonpost.com/politics/20

"The interviews and documents showed the White House’s shocking disregard for Cambodian lives and its failure to assess the impact of U.S. military actions, investigate alleged abuses or hold U.S. personnel to account."

nytimes.com/2023/12/01/opinion

"Why were there so few female scientists? Why was science considered a masculine enterprise? Reflecting on these issues, Keller embarked on two projects: her studies on gender and science, and her biography of US geneticist Barbara McClintock."

nature.com/articles/d41586-023

'Nature reported last month that China’s decoupling from the countries loosely described as the West mirrors its strengthening of science links with low- and middle-income countries (LMICs), as part of its Belt and Road Initiative (see Nature 622, 669–670; 2023).'

nature.com/articles/d41586-023

"Across the U.S., roughly 6 million adults 65 and over have Alzheimer’s disease. Almost two thirds of them are women — a discrepancy that researchers have long attributed to genetics and women’s longer life spans, among other reasons. But there is growing consensus that menopause may also be an important risk factor for the development of dementia later in life."

nytimes.com/2023/11/21/well/mi

UN says Israel has informed it that the visa for the world body's top humanitarian aid official for the Palestinian Gaza Strip and West Bank will not be renewed. Canadian-born Lynn Hastings has been in the post for nearly three years.

On today's final Indie SAGE briefing, Prof Alice Roberts spoke compellingly about the crucial role of the communication of science to society and how open and transparent communication egenders trust and enables the *best* use of science 1/3

When the RPMI is yellow...

"Notably, genes involved in cholesterol biosynthesis and related processes were largely up-regulated or suppressed in response to low (1%) versus normal (5%) or high (10%) CO2 exposure, respectively. This effect was largely independent of pH changes known to occur with varying CO2concentrations"

journals.plos.org/plosbiology/

"Here, Zonozi et al. characterized the T cell response to SARS-CoV-2 vaccination and infection in individuals lacking B cells due to treatment with rituximab or due to a primary immunodeficiency. Not only were virus-specific CD4+ and CD8+ T cells elicited by both infection and vaccination, but the T cells exhibited greater reactivity and proliferative capacity as compared with controls."

science.org/doi/10.1126/scitra

"Goitre was embarrassing, ugly and a subject for humour, so Eggenberger began his presentation with the image of the Madonna from Albrecht Dürer’s Dresden Altarpiece: unimpeachable, unmockable and exhibiting, he claimed, an obvious goitre."

lrb.co.uk/the-paper/v45/n23/jo

"These inequalities are compounded by how various neuroimaging techniques don’t serve Black patients well. Electroencephalography (EEG), which monitors electrical signals that emanate from the brain, is not optimized for Black hair, so participants may have to shave their heads or be excluded from studies completely. Increasingly popular light-based techniques, such as functional near-infrared spectroscopy (fNIRS), have not been corrected for those with higher melanin contents in their skin, which can lead to confounding or less accurate results. This has also been seen with pulse oximetry, a measure of oxygen saturation within your blood, a vital parameter in bedside patient monitoring."

statnews.com/2023/11/29/racism

Getting fully vaccinated dramatically reduces the risk of Long COVID. Rates of Long COVID are finally going down & here's what we know so far: scientificamerican.com/article

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