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"Although epigenetic mechanisms silence most ERVs by generating a repressive environment that prevents their expression (heterochromatin), little is known about mechanisms silencing ERVs residing in open regions of the genome (euchromatin)."

cell.com/molecular-cell/fullte

"The shabby collusion with Stalinism of Sartre and his circle meant that almost any dissident from eastern Europe was regarded as a traitor. Ironically, when his move to the USA was first mooted, he was, in that McCarthyite era, seen by some as dangerously compromised by communism."

literaryreview.co.uk/the-poets

'20 Hard-to-Find Christmas TV Specials Free on YouTube'

From the Muppets to Julie Andrews, from a multiverse of Scrooges to George Lucas's greatest shame, let's take a ride on the holiday nostalgia train together.

colehaddon.substack.com/p/twen

#Christmas #Christmastime #Christmasmovies #movies #film #cinema #TV #television #TVspecials #StarWars #GeorgeLucas #JulieAndrews #JohnDenver #TheMuppets

'Solomon contacted South Carolina senator Strom Thurmond for help. Thurmond insisted the film distributor withdraw the film, telling them, “My folks take their religion very seriously.” The distributor replied, “We take our freedoms very seriously, too.”

lithub.com/when-the-culture-wa

For #AncientSiteSunday the #Hellenistic theatre at Pergamon, #Turkey, built in the 3rd century BC, alterations were made in the #Roman period. It's one of the steepest known ancient theatres. The capacity was about 10,000 spectators.

Photo: C. Bredfeldt  

#Archaeology

"More idiotic things may get done in the name of meeting year-end numerical goals than for any other reason in this industry, so thanks, but I'll try to ignore the recommendation to do them some more, but good and hard this time."

science.org/content/blog-post/

Today is the 75th anniversary of the Universal Declaration of Human Rights!

Adopted by the United Nations General Assembly on 10th December 1948, the declaration was a response to Nazi atrocities and presents the foundational principles for human rights across the world.

Never has it been more important to remind ourselves of their existence and validity.

I invite you to read and share them today! A brief 🧵 1/n

#HumanRights #UDHR #NeverAgain #NieWieder #Gaza
#UN

un.org/en/about-us/universal-d

A meta treinou a sua nova IA para gerar imagens com as fotos do instagram e Facebook. Pagou zero aos utilizadores. Agora vai vender o serviço 👌🏻👌🏻

futurism.com/meta-image-genera

'La semana pasada, cuando se logró una pausa en los ataques para intercambiar rehenes israelíes en manos del movimiento islamista Hamás por presos palestinos, los gazatíes descubrieron también que la mayor biblioteca pública había sido bombardeada y lo interpretaron como un “intento deliberado de destruir libros y documentos históricos”.

elpais.com/planeta-futuro/2023

'Harry Noller had earlier worked in my protein–rRNA interaction lab in West Berlin in 1975 during a sabbatical year when he also, with considerable foresight, learned the new DNA sequencing technique in Fred Sanger's lab in Cambridge. He generously invited me back to Santa Cruz for annual working visits and on one of the last visits in the early 1980s, while staying with Harry, the phone would often ring around midnight followed by long animated conversations on rRNA structure and, since I knew most of the rRNA nucleotides by number, I could follow some of the discussions. When asked: why always at midnight? Harry’s reply was essentially: “I think Carl sits through the evenings with rRNA secondary structure maps, and a bottle of whisky, and by around midnight he needs someone to talk to.”

tandfonline.com/doi/full/10.41

"Después de una vida dedicada a la enseñanza, sobre todo en la provincia de Palencia, Ramiro Curieses, que ha sido maestro de infantil y primaria, docente y director en secundaria, y profesor asociado en la Universidad de Valladolid, está convencido de que una de las claves del buen resultado de las tres comunidades es la escuela rural, que las administraciones autonómicas y los Ayuntamientos protegen pese a su coste para intentar frenar la despoblación"

elpais.com/educacion/2023-12-1

'Another implication of their study is that our ancestors enjoyed a malaria-free existence right up until the neolithic transition 10,000 years ago when, coincident with the shift from nomadic to agrarian lifestyles, Plasmodium falciparum, the parasite responsible for the deadliest form of human malaria, mutated to target Neu5Ac so abundantly present on human cells. It is thought that our more agricultural lifestyle made humans more vulnerable to the malaria-carrying mosquitoes that bred in stagnant pools near settlements.'

theguardian.com/science/2023/d

“A nova entomoteca vai permitir, pela primeira vez, juntar no mesmo espaço toda a colecção de insectos do Muhnac”, refere Roberto Keller, mexicano, curador de entomologia do Muhnac. “É uma biblioteca de insectos!”

publico.pt/2023/12/10/local/no

"The new strategy calls on physicists to begin laying the groundwork for a revolutionary particle collider that could be built on American soil. The machine would collide tiny, point-like muons, which resemble electrons but are more massive."

nytimes.com/2023/12/07/science

#IDMastodon #LongCOVID is associated with reduced measures of exercise performance and skeletal muscle oxidative capacity in the absence of evidence of microvascular dysfunction, suggesting mitochondrial pathology.
ncbi.nlm.nih.gov/pmc/articles/

"BBC film-maker and photographer Sam Rowley captured this astonishing scene of mice apparently squabbling for dropped crumbs after he had spent five cold nights lying flat on a London Underground platform."

theguardian.com/world/2023/dec

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