jonmoulton @jonmoulton@social.cleverlibre.org

Inversin (NPHP2) and Vangl2 are required for normal zebrafish cloaca formation. https://www.sciencedirect.com/science/article/abs/pii/S0006291X23008136 #Morpholino

Etv5a suppresses neural progenitor cell proliferation by inhibiting sox2 transcription. https://www.liebertpub.com/doi/10.1089/scd.2023.0005 #Morpholino

Development and validation of a high throughput screening platform to enable target identification in skeletal muscle cells from Duchenne Muscular Dystrophy (DMD) patients. https://www.biorxiv.org/content/10.1101/2023.05.24.542079v1 Vivo-#Morpholino

A median fin derived from the lateral plate mesoderm and the origin of paired fins. https://www.nature.com/articles/s41586-023-06100-w #Morpholino

Cerebellar granular neuron progenitors exit their germinative niche via Barhl1 mediated silencing of T-Cell Factor transcriptional activity. https://www.biorxiv.org/content/10.1101/2023.05.25.542248v1 #Morpholino

Neural crest E-cadherin loss drives cleft lip/palate by epigenetic modulation via pro-inflammatory gene-environment interaction. https://www.nature.com/articles/s41467-023-38526-1 #Morpholino

Mutation of vsx genes in zebrafish highlights the robustness of the retinal specification network. https://elifesciences.org/articles/85594 #Morpholino

Identification of an α-l-iduronidase (IDUA) M1T mutation in a Chinese family with autosomal recessive mucopolysaccharidosis I. https://nyaspubs.onlinelibrary.wiley.com/doi/full/10.1111/nyas.15016 #Morpholino

DNAJB6 isoform specific knockdown: Therapeutic potential for limb girdle muscular dystrophy D1. https://www.cell.com/molecular-therapy-family/nucleic-acids/fulltext/S2162-2531(23)00135-X Vivo-#Morpholino

Cryo-EM structure of the Mon1–Ccz1–RMC1 complex reveals molecular basis of metazoan RAB7A activation. https://www.pnas.org/doi/10.1073/pnas.2301725120 #Morpholino

Actin filaments accumulated in the nucleus remain in the vicinity of condensing chromosomes in the zebrafish early embryo. https://journals.biologists.com/bio/article/12/5/bio059783/310414/Actin-filaments-accumulated-in-the-nucleus-remain
Fluorochrome-labeled #Morpholino used as a diagnostic probe in a zebrafish to visualize transcription of the miRNA mir-430

Functional characterization of stap2b in zebrafish vascular development. https://faseb.onlinelibrary.wiley.com/doi/10.1096/fj.202201314RRR #Morpholino

A restrictor complex of ZC3H4, WDR82, and ARS2 integrates with PNUTS to control unproductive transcription. https://www.sciencedirect.com/science/article/pii/S1097276523003854 #Morpholino

Recruitment of transcription factor ETS1 to activated accessible regions promotes the transcriptional program of cilia genes. https://academic.oup.com/nar/advance-article/doi/10.1093/nar/gkad506/7199338 #Morpholino

Knockdown of Yap attenuates TAA-induced hepatic fibrosis by interaction with hedgehog signals. https://link.springer.com/article/10.1007/s12079-023-00775-6 #Morpholino

A Role for Microsomal Glutathione Transferase 1 in Melanin Biosynthesis and Melanoma Progression. https://www.sciencedirect.com/science/article/pii/S0021925823019488 #Morpholino

Macrophage Migration Inhibitory Factor on Apoptotic Extracellular Vesicles Regulates Compensatory Proliferation. https://www.biorxiv.org/content/10.1101/2023.06.14.544889v1 #Morpholino

Aquaporins enriched in endothelial vacuole membrane regulate the diameters of microvasculature in hyperglycemia. https://www.biorxiv.org/content/10.1101/2023.01.23.525218v2 #Morpholino

NANOG is required to establish the competence for germ-layer differentiation in the basal tetrapod axolotl. https://journals.plos.org/plosbiology/article?id=10.1371/journal.pbio.3002121 #Morpholino

In Silico Transcriptome-based Screens Identify Epidermal Growth Factor Receptor Inhibitors as Therapeutics for Noise-induced Hearing Loss. https://www.biorxiv.org/content/10.1101/2023.06.07.544128v1 #Morpholino