Knockdown of klotho Leads to Cell Movement Impairment during Zebrafish Gastrulation. https://www.mdpi.com/2410-3888/8/9/440 #Morpholino
DRAM1 confers resistance to Salmonella infection. https://www.tandfonline.com/doi/full/10.1080/27694127.2023.2242715 #Morpholino
Rare variants in CAPN2 increase risk for isolated hypoplastic left heart syndrome. https://www.cell.com/cms/10.1016/j.xhgg.2023.100232/attachment/21afb3a1-a16f-418d-9d4a-525c460d1bd8/mmc1.pdf #Morpholino
Loss of Mtm1 causes cholestatic liver disease in a model of X-linked myotubular myopathy.
https://www.jci.org/articles/view/166275 #Morpholino
(poster) The efficacy of vitamin B6 derivatives in reliving epileptic-like
anomalies in PNPO knockdown zebrafish. https://nckur.lib.ncku.edu.tw/retrieve/225775/%E7%AC%AC%E4%BA%94%E5%B1%86%E5%9C%8B%E9%9A%9B%E7%B6%AD%E7%94%9F%E7%B4%A0%E6%9C%83%E8%AD%B0%20%E6%B5%B7%E5%A0%B1.pdf #Morpholino
Paracrine regulation of neural crest EMT by placodal MMP28. https://journals.plos.org/plosbiology/article?id=10.1371/journal.pbio.3002261 #Morpholino
“Plod2” a Lysyl Hydroxylase Required for HSC Specification. https://www.exphem.org/article/S0301-472X(23)01483-2/pdf #Morpholino
Extracellular Pgk1 interacts neural membrane protein enolase-2 to improve the neurite outgrowth of motor neurons. https://www.nature.com/articles/s42003-023-05223-0 #Morpholino
Ontogenetically distinct neutrophils differ in function and transcriptional profile in zebrafish. https://www.nature.com/articles/s41467-023-40662-7 #Morpholino
Llgl1 mediates timely epicardial emergence and establishment of an apical laminin sheath around the trabeculating cardiac ventricle. https://www.biorxiv.org/content/10.1101/2023.08.14.553249v1 #Morpholino
Lymphocyte pathway analysis using naturally lymphocyte-deficient fish. https://onlinelibrary.wiley.com/doi/pdf/10.1002/eji.202350577 #Morpholino
Alternative splicing of its 5’-UTR limits CD20 mRNA translation and enables resistance to CD20-directed immunotherapies. https://www.biorxiv.org/content/10.1101/2023.02.19.529123v3 #Morpholino
Sequence specificity defines the effectiveness of PPMOs targeting Pseudomonas aeruginosa. https://journals.asm.org/doi/10.1128/aac.00245-23 #Morpholino
Sphingolipid metabolism is spatially regulated in the developing embryo by SOXE genes. https://www.biorxiv.org/content/10.1101/2023.08.10.552770v1 #Morpholino
Sclerotome-derived vascular smooth muscle progenitors contribute to the haematopoietic stem cell specification niche. https://www.biorxiv.org/content/10.1101/2023.08.09.552695v1 #Morpholino
Tmed10 deficiency results in impaired exocrine pancreatic differentiation in zebrafish larvae. https://www.sciencedirect.com/science/article/abs/pii/S0012160623001422 #Morpholino
Protocol for constructing GQD-PMO functionalized FET-biosensor for ultrasensitive exosomal miRNA detection. https://www.sciencedirect.com/science/article/pii/S2666166723004835 #Morpholino
Maternal RNA binding protein with multiple splicing 2 (RBPMS2) is involved in mouse blastocyst formation through the bone morphogenetic protein pathway. https://www.rbmojournal.com/article/S1472-6483(23)00336-X/fulltext #Morpholino
Cfdp1 Is Essential for Cardiac Development and Function. https://www.mdpi.com/2073-4409/12/15/1994 #Morpholino
β-Amyloid targeting nanodrug for neuron-specific delivery of nucleic acids in Alzheimer's disease mouse models. https://www.sciencedirect.com/science/article/pii/S0168365923004972 #Morpholino
It's been all Morpholinos all the time for about 23 years. I'm a scientist with Gene Tools LLC.