Fine-tuning of Fgf8 morphogen gradient by heparan sulfate proteoglycans in the extracellular matrix. https://www.biorxiv.org/content/10.1101/2023.11.02.565243v1 #Morpholino
Candida albicans suppression of neutrophil reactive nitrogen species is rescued by host Hif-1α in vivo. https://www.biorxiv.org/content/10.1101/2023.11.02.565128v1 #Morpholino
Analysis of Vascular Morphogenesis in Zebrafish. https://link.springer.com/protocol/10.1007/978-1-0716-2887-4_24 #Morpholino
Targeting the Expanded TCF4/Fuchs’ Endothelial Corneal Dystrophy CUG Repeat with #Morpholino Peptide Conjugates. https://pubs.acs.org/doi/10.1021/acsomega.3c05634
Pharma's Almanac: Interview with Jon discussing using #Morpholino oligos to alter splicing. https://www.pharmasalmanac.com/articles/modifying-rna-splicing-with-morpholinos
nkx2.3 is responsible for posterior pharyngeal cartilage formation by inhibiting Fgf signaling. https://www.cell.com/heliyon/fulltext/S2405-8440(23)09123-5 #Morpholino
Gαi2-Mediated Regulation of Microtubules Dynamics and Rac1 Activity Orchestrates Cranial Neural Crest Cell Migration in Xenopus. https://www.biorxiv.org/content/10.1101/2023.09.07.556733v2 #Morpholino
Siderophore-Mediated Conveyance of Antibacterial-Antisense Oligomers. https://www.biorxiv.org/content/10.1101/2023.10.30.564798v1 #Morpholino
Regulation of lymphoid-myeloid lineage bias through Regnase-1/3-mediated control of Nfkbiz. https://ashpublications.org/blood/article/doi/10.1182/blood.2023020903/498619/Regulation-of-lymphoid-myeloid-lineage-bias #Morpholino
Characterization of Na+ currents regulating intrinsic excitability of optic tectal neurons. https://www.life-science-alliance.org/content/7/1/e202302232 #Morpholino
Interaction of Integrin αvβ8 With Type I Collagen Promotes Squamous Cell Carcinoma Cell Motility via RAC1 Activation. https://ar.iiarjournals.org/content/43/11/4833.long #Morpholino
SorCS2 binds progranulin to regulate motor neuron development. https://www.cell.com/cell-reports/fulltext/S2211-1247(23)01345-1 #Morpholino
Naringin ameliorates liver fibrosis in zebrafish by modulating IDO1-mediated lipid metabolism and inflammatory infiltration. https://pubs.rsc.org/en/content/articlelanding/2023/FO/D3FO03858K #Morpholino
Distinct roles of core autophagy-related genes in zebrafish definitive hematopoiesis. https://www.tandfonline.com/doi/abs/10.1080/15548627.2023.2274251 #Morpholino
An Induced Pluripotent Stem Cell-Derived Human Blood–Brain Barrier (BBB) Model to Test the Crossing by Adeno-Associated Virus (AAV) Vectors and Antisense Oligonucleotides. https://www.mdpi.com/2227-9059/11/10/2700 #Morpholino
MiniBAR/GARRE1 is a dual Rac and Rab effector required for ciliogenesis. https://www.cell.com/developmental-cell/pdf/S1534-5807(23)00512-9.pdf #Morpholino
The RNA-binding protein CSDE1 promotes hematopoietic stem and progenitor cell generation via translational control of Wnt signaling. https://journals.biologists.com/dev/article/150/21/dev201890/334149/The-RNA-binding-protein-CSDE1-promotes #Morpholino
Sequencing of #Morpholino Antisense Oligonucleotides Using Electron Capture Dissociation Mass Spectrometry. https://pubs.acs.org/doi/10.1021/acs.analchem.3c03621
Specific CaMKIIs mediate convergent extension cell movements in early zebrafish development. https://anatomypubs.onlinelibrary.wiley.com/doi/10.1002/dvdy.665 #Morpholino
Zmym4 is required for early cranial gene expression and craniofacial cartilage formation. https://www.frontiersin.org/articles/10.3389/fcell.2023.1274788/full
#Morpholino
It's been all Morpholinos all the time for about 23 years. I'm a scientist with Gene Tools LLC.