How researchers are exploring AI as a way to boost IVF success. https://elifesciences.org/digests/83662/using-ai-to-boost-ivf-success?utm_source=mastodon&utm_medium=social&utm_campaign=organic
'Now, Takahashi et al. showed that the inheritance of acquired methylation states is not restricted to highly repetitive transposable elements only but can also occur in promoter-associated CpG islands (CGIs) of endogenous genes.'
#IDMastodon @jama_current From the beginning of #COVID19pandemic in mid-March, 2020, through mid-February 2023, nearly 103 mil cases & 1.1 Mil deaths 🇺🇸 Increasing evidence suggests that pregnant patients with #SARSCoV2 infection are at high risk for adverse pregnancy outcomes
https://jamanetwork.com/journals/jamanetworkopen/fullarticle/2803485?utm_source=twitter&utm_campaign=content-shareicons&utm_content=article_engagement&utm_medium=social&utm_term=040823#.ZDEcCflX16Q.twitter
'Limitations in animal models that fail to recapitulate the features of progressive MS provide an immediate dilemma in linking physiologic and pathologic states and in translating preclinical findings to the clinic.'
RT @PauliGroup
To all current and future #zebrafish researchers: Don't miss out on the amazing opportunity to take part in the @MBLScience "Zebrafish Development and Genetics” summer course (July 27 - August 10, 2023). The application deadline is this WEDNESDAY, APRIL 19th!
Please RT!!
'As the new coronavirus spread, pandemic-mitigation measures started to squash flu-transmission rates to record lows. The drop-off was so sharp that several flu lineages may have gone extinct, among them Yamagata, which hasn’t been definitively detected in more than three years despite virologists’ best efforts to root it out.'
Happy birthday to Canadian geneticist Irene Ayako Uchida (1917-2013)! #linocut Uchida is shown surrounded by chromosones, with anomalies (shown with pink arrows) due to radiation exposure, based on one of her research papers. A strand of DNA is hidden in the image (as her watchband).
…
1/n
#printmaking #sciart #genetics #cytology #DNA #histstm #WomenInSTEM #chromosomes
RT @JShendure
Excited to share our lab's latest preprint, led by @CXchengxiangQIU, @bethkarenmartin & Ian Welsh of @JACKSONLAB.
We set out to build a single cell roadmap for all of mouse prenatal development, from single cell zygote to free-living pup.
Preprint: https://tinyurl.com/2nhe4mm9 1/n
'In this issue of Nature Medicine, Cascone et al.2share the latest results of their phase 2 platform trial, NEOSTAR, which suggest that the addition of CTLA-4 blockade to neoadjuvant anti-PD-1 plus chemotherapy may augment anti-tumor responses.'
#LungCancer #Immunology #TumorImmunology #immunotherapy #checkpointinhibitors
There are some drawbacks, with monoclonals being more vulnerable to the emergence of escape variants than vaccines, but this is a sensible proposal (the other major drawback is price, but that is a regulatory and not scientific issue).
"As a dual-purpose platform technology, monoclonal antibodies (mAbs) can close the gap in prophylaxis that exists with a vaccine-only approach and serve as a therapeutic option where needed. Thus, the development of an arsenal of ready-to-use prophylactic and therapeutic mAbs could help to rapidly contain future infectious disease outbreaks before they evolve into pandemics."
'En unos meses abrirá en Cala Montjoi (Girona) su proyecto más ansiado, por el que lleva esperando, por problemas con las obras, protestas medioambientales y pandemia, ocho años. En junio inaugurará elBulli 1846, un museo que pretende guardar la esencia y la memoria de todo lo vivido durante años en elBulli, cerrado desde 2011, pero que su artífice pretende que no caiga en el olvido, sobre todo para quienes no vivieron aquella locura gastronómica.'
Twitter did the same thing with Mastodon in December, then suspended journalists like me who pointed that out https://www.theverge.com/2022/12/15/23512113/twitter-blocking-mastodon-links-elon-musk-elonjet
RT @bolanosjuanp
Are you interested or know potential PhD candidates on Brain Metabolism during Aging in Salamanca (Spain)? We offer two positions under the MSCA ETERNITY Network to start in July 2023! Eligibility and applications (projects DC8 & DC9) in http://www.projecteternity.eu Deadline 15 April
That's a bingo:
'O problema não está em que haja presença partidária e marca partidária na governação, está na cada vez maior desqualificação e mediocridade do pessoal político nos partidos. E como são o que são, desertificam tudo à sua volta.'
'The study, published in the journal Nature, focused on swabs taken from surfaces in early 2020 at the Huanan Seafood Wholesale Market, a large market where many of the earliest known Covid patients had worked or shopped. The Chinese scientists had posted an early version of their genetic analysis of those samples in February 2022, but at the time downplayed the possibility of animal infections at the market.'
https://www.nytimes.com/2023/04/05/science/china-virus-origins-racoon-dogs.html?
'Rich with words and references from Indigenous and Afro-Brazilian cultures, the modernist novel was hailed as a classic upon its publication in 1928, and has long been seen as an allegory for Brazil’s unique cultural blend. Faced with criticism of the book’s uncredited reliance on anthropological research, Andrade offered up, in an open letter, a typically insouciant response: “I copied Brazil.”
Investigadores Ibero-Americanos! 🧠
Gran oportunidad para publicar gratuitamente junto al periodico Progress in Brain Research de Elsevier.
Revisiones systematicas y estudios experimentales sobre "cerebro y matematicas" con fMRI, EEG, ERP, TMS y tES. #Brain #Math #Neuroscience DM for details.
I've worked on all of science, from B cells to T cells.
https://fellowsherpa.com