Thiago Carvalho @cyrilpedia@social.cleverlibre.org

Today’s weird fact from nature: When fruit #flies see other dead fruit flies, their life spans are cut short. Other species also undergo analogous physiological changes when seeing their dead 🪰

https://theconversation.com/seeing-dead-fruit-flies-is-bad-for-the-health-of-fruit-flies-and-neuroscientists-have-identified-the-exact-brain-cells-responsible-207283

#death #science

While we’re worrying about AI, the bollards are planning a global revolution...

#OTD 16 July 1942 The government of Vichy France orders the mass arrest of 13,152 Jews who are held at the Vélodrome d'Hiver in Paris before deportation to Auschwitz.

The Evolutionary History of Drosophila simulans Y Chromosomes Reveals Molecular Signatures of Resistance to Sex Ratio Meiotic Drive https://doi.org/10.1093/molbev/msad152 #science #evolution #biology #genome #evolgen_paper

'The role of perceived experts (i.e., medical professionals and biomedical scientists) as potential anti-vaccine influencers has not been characterized systematically.'
#Preprint

https://www.medrxiv.org/content/10.1101/2023.07.12.23292568v1

'For the convenience of human experimentalists and caretakers, and to decrease costs, mice are generally housed at environmental temperatures below their thermoneutrality. Our comfort and fiscal frugality come at costs that may include inappropriate interpretation of findings and even compromised translatability of experimental findings to human physiology and disease.'

https://www.nature.com/articles/s42255-021-00372-0

When Juan speaks, I pay attention :)

'Using a high throughput compatible assay that measures real-time translocation of the glucose transporter glucose transporter 4 (GLUT4), we identified small molecules that potentiate insulin action. In vivo, these insulin sensitizers improve insulin-stimulated GLUT4 translocation, glucose tolerance, and glucose uptake in a model of IR'

#metabolism #insulin

https://www.cell.com/cell-chemical-biology/fulltext/S2451-9456(23)00190-3

#cytokines as #biomarkers for therapeutic success in #NSCLC #nsclctrial #Immunotherapy #pd1 #pdl1 utilizing #MachineLearming , link to downloadable PDF https://bit.ly/3NTxfTt

“They have left no doubt that their pledges were deployed for cynical political purposes”

https://www.theguardian.com/us-news/2023/jul/16/big-oil-climate-pledges-extreme-heat-fossil-fuel

'She also points out that some viruses such as Ebola and Zika don’t have a known latent phase, yet “we know people where, six months after recovery, you get transmission of #Zika, or #Ebola, or reactivation of problems . . . That means that full length RNA is there and can resume production.”
#Virology

https://www.bmj.com/content/382/bmj.p1156

'In this Review, we present current knowledge on the role of MDSCs in the immunotherapy of melanoma. We describe the accumulation, infiltration, and immunosuppressive functions of MDSCs in the tumor microenvironment (TME) as well as existing therapeutic strategies to target them in melanoma-bearing hosts. A special focus is placed on preclinical studies and clinical trials applying MDSC inhibition to overcome resistance to ICIs.'

#immunology #immunotherapy #immunooncology

https://www.jci.org/articles/view/170762

"The Blues is personal catastrophe lyrically expressed."
- Cornel West

https://aeon.co/videos/cornel-west-navigates-the-messy-business-of-meaning-making-on-a-whirlwind-drive

Oil companies promise action on #climate, but experts says it’s all talk: “fossil fuel companies have only doubled down on their oil- and gas-filled business models.” https://www.theguardian.com/us-news/2023/jul/16/big-oil-climate-pledges-extreme-heat-fossil-fuel #climatechange

"Rishi Sunak will announce on Monday that he will CAP the number of students wanting to study "low-value" degrees."

Want to know what I think?

https://www.theguardian.com/education/2023/jul/14/rishi-sunak-force-english-universities-cap-low-value-degrees