#introduction time!
I do #appliedmath at Dartmouth College. I am all about using #math to model #complexsystems + #networks in #compbio, #compneuro & #compsoc, and to improve methods in #datascience and #ml. (Have worked on #emergence of correlation patterns and #causalinference and now getting into #explanaible #machinelearning for #publichealth / #mentalhealth.)
Would love to connect with the #mastodonscience crowd, #womeninmath, #womeninstem, #python, #dataviz folks, and fellow #cat lovers!
"Discussions around neurodivergence and neurodiversity have become more common over the past few years. However, this increased awareness has not necessarily led to better support and understanding."
"By his mid-20s, Mr. Holmes thought about what was ahead for him — sickle cell emergency after emergency, begging for help in Alabama hospitals that saw a Black man and assumed him to be a drug addict — and he started to think about ending his life. “Every time I tried anything, the disease would come and knock me away,” he remembered. “You get tired. You get worn out.”'
https://www.nytimes.com/2023/10/30/opinion/sickle-cell-gene-therapy-crispr.html
Friends - we are looking for reviewers for a #genomics focused package - sourmash.
We’d like atleast one person with a solid genomics background but the second can be more packaging, usability, docs, etc etc focused. Please spread the word in your communities!!
more here:
https://pyopensci.discourse.group/t/looking-for-genomics-package-reviewers/388
UN agency in Gaza says urgent ceasefire 'matter of life and death' for Palestinians
'A study published in 2020, which drew together multiple pieces of research to track the health of almost 50,000 over-65s, showed the incidence rate of new cases of dementia in Europe and North America had dropped 13 per cent per decade over the past 25 years — a decline that was consistent across all the studies.'
https://www.ft.com/content/184f6e81-d9ce-4a14-84f0-5190ea36e798
@tg9541 There are vague references to a 2020 study then this "Grodstein’s study, published earlier this year, made a notable discovery. While signs of vascular disease in the brain appeared to have decreased over time, the extent of the distinctive markers of Alzheimer’s in the brain stayed the same. This led the team to hypothesise that “any decrease in clinical Alzheimer’s dementia might be due in part to better cardiovascular health and in part to increased resilience to [the causes of] Alzheimer’s”, such as amyloid plaque, rather than to a decrease in Alzheimer’s pathology itself." which I think refers to this
https://jamanetwork.com/journals/jamaneurology/article-abstract/2801809
A new episode of the EMBO podcast is out. I spoke with Hsiao-Han Chang, Gytis Dudas, and Hedvig Tamman about viruses, hosts, spillovers, public health... And also starting a new lab, the challenges of mobility, mentorship, and Die Hard Dracula.
#EMBOPodcast #scicomm #SciencePodcast #Virology #Evolution #Microbiology
“Even people who are really knowledgeable and who have a lot of experience out in the field were surprised to see how fast these forests were going down the drain,” says ecophysiologist and Annual Review of Plant Biology author Henrik Hartmann.
Read more:
🌳 @KnowableMag https://arevie.ws/DyingTrees_KM
🌳 Knowable en español https://arevie.ws/DyingTrees_KEE
🌳 Annual Review of Plant Biology https://arevie.ws/Deforestation_EG48
'A study published in 2020, which drew together multiple pieces of research to track the health of almost 50,000 over-65s, showed the incidence rate of new cases of dementia in Europe and North America had dropped 13 per cent per decade over the past 25 years — a decline that was consistent across all the studies.'
https://www.ft.com/content/184f6e81-d9ce-4a14-84f0-5190ea36e798
Academic rankings: The tide begins to turn https://www.universityworldnews.com/post.php?story=20231024130858697
Great piece by Chris Brink about academia's increasingly critical stance toward university rankings.
Brink discusses the @tweetsunl expert group report on rankings (https://www.universiteitenvannederland.nl/en_GB/nieuws-detail/nieuwsbericht/915-p-dutch-universities-to-take-different-approach-to-rankings-p.html) and points out that UNL "is the first national association of universities that has moved beyond rhetoric towards action to counteract the well-known concerns about rankings".
New at Media Nation: One year later, calculating the damage that Elon Musk has done to Twitter. https://dankennedy.net/2023/10/30/one-year-later-calculating-the-damage-elon-musk-has-done-to-twitter/
It has been a few years that I have been this excited about work coming from our lab! Our latest preprint:
https://www.biorxiv.org/content/10.1101/2022.12.16.520755v3
rests on a collaboration with Carsten Duch in Mainz:
https://enb-idn.biologie.uni-mainz.de/prof-dr-carsten-duch/
and describes #neuroscience experiments on a type of #motorlearning in #Drosophila that was first described in 1991:
https://link.springer.com/content/pdf/10.1007/BF00194898.pdf
Now, we present which genes are required in which neurons for this type of learning to take place.
1/6
"Briefing documents released 27 October suggest that FDA examiners have zeroed in on this possibility, and it is slated to become a key discussion point when advisors meet to discuss the risks and benefits of exa-cel next week.
In particular, the FDA flagged two potential shortcomings in assays that Vertex and CRISPR Therapeutics used to determine exa-cel’s risk of causing off-target changes"
"Yet, resident and circulating Treg had distinct TCR repertoires, and each LN contained exclusive clonal subpopulations of resident Treg. Our results demonstrate that, similar to conventional T cells, Treg can form resident memory-like populations in LNs after adaptive immune responses"
#immunology
"Because of the attritional nature of contemporary peer review (and the level of aggression frequently encountered), successes in both papers and grants are nowadays likely to be met not with celebration, but a sense of exhausted relief. The pleasure is always fleeting."
@TIR_scienceblog
https://totalinternalreflectionblog.com/2023/10/29/a-riposte-to-the-red-queens/
Postdoctoral Fellow: Molecular Genomics
Imperial College London
Interested in how cells control their DNA replication? So are we! Join us for a postdoc to explore how key regulators affect genome stability.
See the full job description on jobRxiv: https://jobrxiv.org/job/imperial-college-london-27778-postdoctoral-fellow-molecular-genomics/?feed_id=63771
#ScienceJobs #hiring #resear...
https://jobrxiv.org/job/imperial-college-london-27778-postdoctoral-fellow-molecular-genomics/?feed_id=63771
This is so cool! There is an annual mass #biodiversity experiment in Danish schools, which this year involved 30,000 kids collecting + examining samples of moss + lichen. Only 5% have been examined so far but they've already discovered 5 species of water bear unknown to science.
Ht @jeppe
https://uddannelse.social/@jeppe/111322661213816133
The first message between two computers on ARPANET was sent #OTD in 1969. The “LO” of “LOGIN” was successfully transmitted and then one of the systems crashed.
Charles Kline’s IMP Log: “Talked to SRI host to host.”
Image: UCLA Kleinrock Center for Internet Studies
I've worked on all of science, from B cells to T cells.
https://fellowsherpa.com