Thiago Carvalho @cyrilpedia@social.cleverlibre.org
I've worked on all of science, from B cells to T cells.
https://fellowsherpa.com
Joined Nov 2022
Thiago Carvalho
boosted
Online Now: Epigenetic pioneering by SWI/SNF family remodelers https://www.cell.com/molecular-cell/fulltext/S1097-2765(23)00916-4?rss=yes&utm_source=dlvr.it&utm_medium=mastodon
"Although these systems hold great promise for advancing our understanding of lung biology and disease, there are still many challenges, including efficient derivation of terminal cellular maturity and structural complexity, as well as developing standardized workflows for scalability and reproducibility. Here, we outline the most recent developments in lung organoid systems and their implications for disease modeling that could set the stage for further breakthroughs in this exciting and rapidly evolving field."
#Organoids
"I'm not particularly impressed with Large Language Models as they apply to natural human languages - "plausible sentence generators" is the phrase that I've seen that sums up my beliefs about them. But for things that are less complex than natural language, these techniques have more real-world uses. Coding is one, naturally, because programming languages are smaller and more orderly than human ones. The language of protein sequences is another example"
@Daojoan I still want to see the full version of Jason Segal's dracula puppet musical!
Thiago Carvalho
boosted
@cyrilpedia suddenly all I want in the world is a Nosferatu musical
Thiago Carvalho
boosted
SNSF launches a call for National Centres of Competence in Research (NCCRs) on behalf of the Confederation. NCCRs are long-term research projects on topics of strategic importance for Switzerland. Submission deadline for declarations of intent: 15.02.2024
https://www.snf.ch/en/fL8djR9hWqcJ82pE/news/national-centres-of-competence-in-research-nccrs-the-snsf-launches-a-new-call
'He told me he had started writing the song for a prospective musical version of Nosferatu years before, but never finished it. Around the time we were recording, Meat Loaf had lost his voice, and after it was a hit he always used to say: “Dang. That song should have been mine!”
"The sparse and stochastic nature of reprogramming has obscured our understanding of how transcription factors drive cells to new identities. To overcome this limit, we developed a compact, portable reprogramming system that increases direct conversion of fibroblasts to motor neurons by two orders of magnitude"
Thiago Carvalho
boosted
"FEIRA DO PRATO FALANTE 5 & 6 de Dezembro com visitas das 12h às 20h." @almeida_felipa featuring @hunchbacksociety & more.
Thiago Carvalho
boosted
Androgen deprivation + anti-PD1 trial for #prostatecancer.
"These data provide a reasonable therapeutic rationale to combine ADT with immunotherapy, thus leveraging anti-tumor immunity while mitigating the ADT-mediated induction of suppressive mechanisms. To that end, we designed and initiated the PRIME-CUT Phase II trial (NCT03951831) treating men with metastatic castration-sensitive prostate cancer (mCSPC) with a combination of standard of care chemo-hormonal therapy and anti-PD-1 immunotherapy using the anti-PD-1 immunotherapy cemiplimab."
#immunology #immunotherapy
https://www.cell.com/cancer-cell/fulltext/S1535-6108(23)00362-8
Thiago Carvalho
boosted
While I wait for my copy of my friend Dann McDorman's debut novel "West Heart Kill" to arrive, I enjoyed this podcast interview.
Thiago Carvalho
boosted
"When Claudia Goldin received her Nobel Memorial Prize in Economics, she was only the third woman to receive the award after Esther Duflo (2019) and Elinor Ostrom (2009). It was the first time in the history of the 54-year-old prize that women held more Nobels in economics than the uncles of Larry Summers (Paul Samuelson and Kenneth Arrow). An anecdote, but it illustrates the level of representation of women in economics."
Thiago Carvalho
boosted
"Large outbreaks of diseases that primarily kill children are spreading around the world, a grim legacy of disruptions to health systems during the Covid-19 pandemic that have left more than 60 million children without a single dose of standard childhood vaccines."
https://www.nytimes.com/2023/11/25/health/vaccines-children-zero-dose.html
Thiago Carvalho
boosted
I second Mark Kermode: Ken Loach's Land & Freedom (1995) is a superb film.
Watch it if you have the chance.
Thiago Carvalho
boosted
Just when I'd finally found good kimchi in Lisbon!!
"The antibiotic resistome was further illustrated in traditionally fermented food samples, and antibiotic-resistant bacteria were isolated from approximately 90% of the retail kimchi and all artisan cheeses assessed in this pilot screening."
#Preprint #Microbiology #antibioticresistance
Thiago Carvalho
boosted
His historical works include biographies of Oliver Goldsmith, Muhammad, and George Washington, as well as several histories of 15th-century Spain that deal with subjects such as the Alhambra, Christopher Columbus, and the Moors. Irving served as American ambassador to Spain in the 1840s.
*Insert your "this is deeply unfair to drug dealers" comment here*
'Mohamed Adow, the director of the thinktank Power Shift Africa, said: “The Saudi government is like a drug dealer trying to get Africa hooked on its harmful product."
https://www.theguardian.com/environment/2023/nov/27/revealed-saudi-arabia-plan-poor-countries-oil
Thiago Carvalho
boosted
Cancer concerns us all one way or the other.
With
https://nitter.cz/search?q=%23EUCancerPlan
, we're taking important steps & changing the prognosis for every cancer patient & survivor, working on better prevention and earlier detection.
28
https://nitter.cz/search?q=%23EU4Health
-financed projects:
https://europa.eu/!7yFV8y
https://nitter.cz/search?q=%23HealthUnion
🐦🔗: https://nitter.cz/EU_Health/status/1729403417796202511#m
[2023-11-28 07:34 UTC]
'(...) even if European far-right parties do not overturn democracy, they can pull political debate on to their turf. The most obvious trait they share is a powerful hostility towards immigration — particularly of Muslims — and a willingness to contemplate measures that have previously been dismissed as impractical, intolerable or illegal.'
https://www.ft.com/content/8384228d-8156-4134-8eb4-035c068704b9
"The first thing you should know about Social Security is that the actual numbers don’t justify the apocalyptic rhetoric one often hears, not just from the right but from self-proclaimed centrists who want to sound serious."
https://www.nytimes.com/2023/11/27/opinion/nikki-haley-social-security.html
I've worked on all of science, from B cells to T cells.
https://fellowsherpa.com
Joined Nov 2022
