When the RPMI is yellow...
"Notably, genes involved in cholesterol biosynthesis and related processes were largely up-regulated or suppressed in response to low (1%) versus normal (5%) or high (10%) CO2 exposure, respectively. This effect was largely independent of pH changes known to occur with varying CO2concentrations"
https://journals.plos.org/plosbiology/article?id=10.1371/journal.pbio.3002401
"Here, Zonozi et al. characterized the T cell response to SARS-CoV-2 vaccination and infection in individuals lacking B cells due to treatment with rituximab or due to a primary immunodeficiency. Not only were virus-specific CD4+ and CD8+ T cells elicited by both infection and vaccination, but the T cells exhibited greater reactivity and proliferative capacity as compared with controls."
#covid19 #covid #Immunology
https://www.science.org/doi/10.1126/scitranslmed.adh4529#supplementary-materials
"Goitre was embarrassing, ugly and a subject for humour, so Eggenberger began his presentation with the image of the Madonna from Albrecht Dürer’s Dresden Altarpiece: unimpeachable, unmockable and exhibiting, he claimed, an obvious goitre."
https://www.lrb.co.uk/the-paper/v45/n23/jonah-goodman/a-national-evil
"These inequalities are compounded by how various neuroimaging techniques don’t serve Black patients well. Electroencephalography (EEG), which monitors electrical signals that emanate from the brain, is not optimized for Black hair, so participants may have to shave their heads or be excluded from studies completely. Increasingly popular light-based techniques, such as functional near-infrared spectroscopy (fNIRS), have not been corrected for those with higher melanin contents in their skin, which can lead to confounding or less accurate results. This has also been seen with pulse oximetry, a measure of oxygen saturation within your blood, a vital parameter in bedside patient monitoring."
Getting fully vaccinated dramatically reduces the risk of Long COVID. Rates of Long COVID are finally going down & here's what we know so far: https://www.scientificamerican.com/article/long-covid-rates-appear-to-be-decreasing/
The new issue of @genomeresearch is now live. Follow the link to new research on the transcription factor repertoire in a liver cell line, autonomous exons in the human genome, and more! https://tinyurl.com/Genome-Res-33-11
BREAKING: Massachusetts has become the second US state to report a large uptick in the number of child pneumonia cases amid a mysterious viral outbreak in China, per NYP.
"The immunology behind the pandemic and, even more importantly, guidance to prevent severe disease, began to be lost in a sea of misinformation and deliberate disinformation, turning the pandemic into a political football. This led to confusion, and tragically, to decisions that unnecessarily increased morbidity and mortality. It is incumbent on us to understand what happened so we can be better prepared for future crises and, moreover, draw lessons for science communication more generally."
"As algas não servem só para alimentar peixes. Na agricultura, estes organismos podem também servir de suplemento vitamínico às alfaces, espinafres ou framboesas. O projecto que põe em prática esta tese está a ser desenvolvido pela Universidade do Algarve, através da GreenColab"
"The math is simple, even mind-numbingly obvious—a pathogenic n+1 that epidemiologists have seen coming since the pandemic’s earliest days. Now we’re living that reality, and its consequences. “What I’ve told family or friends is, ‘Odds are, people are going to get sick this year,’” Saskia Popescu, an epidemiologist at the University of Maryland School of Medicine, told me."
https://www.theatlantic.com/health/archive/2023/11/flu-season-winter-sickness-covid/676173/
Oyakodon. Glazed #stoneware by @hunchbacksociety
#proverbs #proverbios #ceramics #plate #pottery #artgallery #artmastodon @madparreira.bsky.social
Nice review by Kirsty Wan and Rebecca Poon from Exeter on the diverse patterns and mechanisms of multiciliary coordination.
https://doi.org/10.1016/j.ceb.2023.102286
#cilia #microscopy #CellBiology #biophysics
" Tras varios encontronazos con la Iglesia y el régimen franquista, Llidó decidió marcharse a Chile, donde reforzó su compromiso con el pueblo y estableció relación con el presidente Salvador Allende, del que se cumplen 50 años de su muerte. Tras el golpe de Estado de Augusto Pinochet en 1973, fue detenido, torturado y asesinado por la dictadura, como sentenció un juez, si bien su cuerpo nunca se pudo recuperar. "
Extreme heat and drought conditions in Europe could occur much earlier than previously thought 👇
https://phys.org/news/2023-12-century-extreme-drought-conditions-europe.html?s=09 #ClimateChange #ClimateCrisis #Hazards #Drought #ExtremeHeat
'The number of desaparecidos in Argentina at that stage has been calculated at 1,022. In October, at the Waldorf-Astoria hotel, Kissinger told Guzzetti, "the quicker you succeed the better." The steep and rapid climb into the tens of thousands was incited.'
https://archive.vanityfair.com/article/2004/12/kissinger-declassified
Latest post of UK Covid situation is here:
https://open.substack.com/pub/christinapagel/p/latest-covid-situation-in-the-uk-110?r=8zv6v&utm_campaign=post&utm_medium=web
TLDR: good news as Covid levels are lower than last winter and falling, as we go into the Christmas season. Flu also remains much lower than last year.
Population Genomics of the Facultatively Sexual Liverwort Marchantia polymorpha https://doi.org/10.1093/gbe/evad196 #science #evolution #biology #genome #evolgen_paper
'Now with the new telomere2telomere long read enabled references I figured it would be fun to try asking a similar question. What’s the utility of long reads?3 I.e. how much more of the genome to long reads let us address.'
https://aseq.substack.com/p/the-utility-of-long-reads?r=f3eze&utm_campaign=post&utm_medium=email
I've worked on all of science, from B cells to T cells.
https://fellowsherpa.com