Thiago Carvalho @cyrilpedia@social.cleverlibre.org
I've worked on all of science, from B cells to T cells.
https://fellowsherpa.com
Joined Nov 2022
Thiago Carvalho
boosted
Welp
This broke my brain
Cyclosporine A as a vaccine adjuvant to induce TRegs is something that would never have occurred to me, let alone it leading to *enhanced* antibody responses
'In 1927, W. Somerset Maugham wrote “Ashenden: or, The British Agent,” about a writer who is recruited into British intelligence by a handler called R. During the war, Maugham had been a spook; he was recruited after “Of Human Bondage” came out. Writers make good joes (as Herron might say): they’re keen observers, and they tend to know languages. (Maugham had French and German.)'
https://www.newyorker.com/magazine/2022/12/05/is-mick-herron-the-best-spy-novelist-of-his-generation
Thiago Carvalho
boosted
The US National Academies will hold a workshop on Earth System tipping points, cascading impacts and interacting risks in January: https://www.nationalacademies.org/event/01-17-2023/workshop-on-tipping-points-cascading-impacts-and-interacting-risks-in-the-earth-system?mc_cid=3d0ad5185d&mc_eid=48f916cbb4
'In Franklin’s day, sexism ran rampant in science. Her own father, judging science no career for a woman, actively discouraged her aspirations. Her doctoral supervisor at Cambridge, eventual Nobel Laureate Ronald G.W. Norrish, called her “stubborn and difficult to supervise” and offered little support. James Watson, whose Nobel Prize hinged in large part on her work, referred to her in his memoir as “Rosy” (against her preference), and stated that, because of her “belligerent moods,” colleagues knew she “either had to go or be put in her place.”
Thiago Carvalho
boosted
On this day in 1822: Louis Pasteur born, invented pasterisation and developed 1st rabies vaccine #ThisDayInBiotech
Thiago Carvalho
boosted
#Sexism pushed Rosalind Franklin toward the scientific sidelines during her short life, but her work still shines on her 100th birthday https://theconversation.com/sexism-pushed-rosalind-franklin-toward-the-scientific-sidelines-during-her-short-life-but-her-work-still-shines-on-her-100th-birthday-139249 #science #Women #WomenInSTEM
Thiago Carvalho
boosted
What a cool paper!
Objective definition of the surgical gestures associated with better / worse outcomes!
Surgery has always had the problem that interventions retain strong user-specific variability, whereas this leverages more standardised robotic movements, to correlate with outcomes.
Can see potential to impact on practice / training.
@gpollara As they point out here, the path is arduous but clear:
"The solution to the field’s analytical abundance is benchmarking: the testing — ideally by neutral parties — of multiple methods, often applied to several kinds of data set, to determine which method works best for different purposes. "
Thiago Carvalho
boosted
Biologist J. B. S. Haldane once quipped that if there's a God, the Creator seems to have “an inordinate fondness for beetles.”
Why? Well, 1/2 of species described in #science are insects (among eukaryotes). Of those, >1/3 are beetles, at ~400,000 known species.
I’m especially fond of these critters bc I began my career working with Plagiodera versicolora, a particularly cute beetle.
Now some entomologists suspect there may be just as many parasitic wasps, but that’s a tale for another day.
Thiago Carvalho
boosted
Delighted to say our #Monkeypox/#MPOX paper is now out as a preprint:
https://www.medrxiv.org/content/10.1101/2022.12.22.22283648v1
It's a bit of a beast, but a thread of the results we've found...🧵
Thiago Carvalho
boosted
Hi all, instead of a re- #introduction after moving instances, I'd like to introduce you to my graduate student Peter Salvino, who passed away under tragic circumstances last week.
Because of his way too early passing, most of you didn't get to know him. So I wanted to make sure my #neuroscience community knows how brilliant and kind a scientist he was. Peter wore many hats in the lab. Being my very first student, he built with me, and knew the ins and outs of every bit of hardware and software. He was also a masterful engineer and inventor, and had a keen scientific mind. He knew what the big questions in the field were and was completely fearless in going after them. We will slowly publish all his great contributions, so you will read his name again.
Most importantly, he was so generous to his lab mates. He helped every single person in the lab, with such selflessness and genuine humbleness. He was really loved by all of us. This is such a huge loss to our field. He was destined to greatness.
Peter's family has set up a GoFundMe campaign to help support research similar to his at Northwestern. They welcome any contributions to honor the memory of this amazing human being.
Thiago Carvalho
boosted
Fascinating article by Will Chavez in High Country News about Jennie Ross Cobb, the first known Native American female photographer. Most of her photographs, including the one below, were made between 1902 and 1905.
#Photography #Cherokee #JennieRossCobb #Indigenous
https://www.hcn.org/issues/54.4/indigenous-affairs-photos-images-from-the-first-known-native-american-female-photographer
Thiago Carvalho
boosted
December 27, 1831, HMS Beagle with Charles #Darwin on board departs Plymouth harbor, England, for a survey of South America. The rest is history ⛵
Thiago Carvalho
boosted
Our recent paper about rangers (or rather the lack of: https://www.nature.com/articles/s41893-022-00970-0) made the cover of Nat Sustainability 🥳
I hope it will help attract the attention of #COP15 #biodiversity folks so that they start considering the issue seriously.
Since the cover mentions nothing else, I am starting to wonder if the website is not simply reading cookies and generating a specific cover for any author...🤔
Thiago Carvalho
boosted
Maybe the greatest contemporary street photographer and one of the greatest ever, Alex Webb is known for his images full of colour, people, complexity and reading planes. He takes this shot in Nuevo Laredo, Mexico: one of the masterpieces of the stunning book “La Calle”, which collects his shots taken in Mexico between 1975 and 2007. Since 1979 Alex Webb is one of the leading photographers of Magnum Photos
"Most jazz musicians practice by themselves; “woodshedding” is part of the life. But Rollins’s notion of practicing expanded into nearly all of his life, to the point where you wonder whether he’s practicing in preparation for the thing or if practice is the thing itself — whatever the thing may be: a gig, a recording, a new level of musical expression, a higher consciousness, the next life."
https://www.nytimes.com/2022/12/20/books/review/saxophone-colossus-aidan-levy.html
Thiago Carvalho
boosted
Depression is the most common mental health condition in the world, so understanding it has major consequences for many people.
Thanks to improving research, we now have a better idea of what people experience and how their condition progresses over time. https://ourworldindata.org/what-is-depression
Thiago Carvalho
boosted
1. "Language models generalize beyond natural proteins"
https://www.biorxiv.org/content/10.1101/2022.12.21.521521v1
They asked the question: can protein language models extend natural proteins and actually serve as an engine for generative design? The answer is seemingly yes.
Copied from: https://www.linkedin.com/in/elliot-hershberg
Thiago Carvalho
boosted
What an incredible man he is- to stay so calm in the face of such challenges. I had to fulfil my responsibility’: Fauci on his career, Covid and stepping down https://www.theguardian.com/us-news/2022/dec/25/fauci-interview-covid-trump-biden?CMP=Share_iOSApp_Other
'But even though the proliferation of wet-lab techniques and analytical methods has expanded access to single-cell studies, it has also muddied the waters for researchers trying to pick the best approach. The online single-cell RNA tools catalogue, scRNA-tools, lists nearly 1,400 software packages that turn single-cell data into scientific insights. How are researchers supposed to choose?'
I've worked on all of science, from B cells to T cells.
https://fellowsherpa.com
Joined Nov 2022
