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RT @group_laser
Please RT. Are you looking for an academic position in Cambridge? We are opening 3 positions at the Department of Chemical Engineering in areas of Biotechnology and Fluid mechanics. Deadline, 6 of January!
@cebcambridge

'We systematically reviewed gene editing clinical trials from ClinicalTrials.gov using a searching strategy that included all different gene editing technologies, followed by two rounds of independent assessment based on the inclusion and exclusion criteria, data extraction, and review of the background publications. 76 trials met our inclusion criteria including 30 studies on genetically engineered T-cell therapies for cancer, 19 studies on virus infections, and 26 studies on monogenic diseases.'

medrxiv.org/content/10.1101/20

'The hysteria around immigration has been all the more marked in the last few days because of record net migration numbers. Conservatives and Labour’s instinct seems to be to shout even louder about reducing it. But this could be an poor political calculation for both parties: recent research by the Institute for Public Policy Research think tank suggests the British public are less bothered by immigration and more positive about increasing it.'

newstatesman.com/quickfire/202

Delivering ICIs to the brain

"Assessment of the BBB/BTB physical and molecular properties, anti-PD1 penetration and uptake, and its impact on immune cell trafficking, along with monitoring of treatment response rates and durability are used to test our hypothesis and support the effective integration and translation to the clinics of brain cancer immunotherapy with MB-FUS and immune checkpoint blockade."

science.org/doi/10.1126/sciadv

RT @Dev_journal
Age reprogramming: cell rejuvenation by partial reprogramming

An #OpenAccess Spotlight from Prim Singh and Assem Zhakupova highlighting recent work and open questions in the age reprogramming field.

journals.biologists.com/dev/ar

The existence of messenger RNA (mRNA) and its role in producing protein was demonstrated in 1961 by several groups, coming at the problem from different angles. It is a remarkable story of early molecular biology, told well by @matthewcobb in his essay "Who discovered messenger RNA?"

sciencedirect.com/science/arti

Now "mRNA" is trending on Twitter as the target of anti-vaccine posts. Who would have thought that mRNA would be reviled and feared 60 years after its discovery?

#introduction

Cell biologist, student of the #cytoskeleton, professor and dean at The Rockefeller University in #NYC.

Interested in #centrosomes, #cilia, and science #education, #outreach and #policy.

Team's busy with next-gen super-res probes! Here's a large COS cell transfected vimentin-ALFA, imaged by 3D DNA-PAINT using @massphoton@twitter.com new anti-ALFA nanobody. Sample prepared by Channa Jakobs, PAINT set up with the help of @FriedlKaroline@twitter.com

Our Sussex Neuroscience 4-year PhD Programme is open for applications! Deadline Feb 23rd, for Sept 2023 entry. Brilliant community of students and supervisors, and a choice of >40 labs for rotations- come and join us by the sea! sussex.ac.uk/research/centres/ #neuroscience #phd #sussex #compneuro

RT @immunoboys
"Selective retention of virus-specific tissue-resident T cells in healed skin after recovery from herpes zoster"
@NatureComms 2022
nature.com/articles/s41467-022

I was today years old when I learned that Louis Pasteur referred to the filiform microbe B. anthracis as "vibrions baguettes."

Bacterial breadsticks!

(I know that "baguette" in French is used in a number of contexts beyond the baker's oven, but allow me my moment's chuckle.)

'We use data on changes in the in vivo concentration of monoclonal antibodies, and the associated protection from COVID-19, over time to model the dose-response relationship of monoclonal antibodies for prophylaxis. We estimate that 50% protection from COVID-19 is achieved with a monoclonal antibody concentration of 939-fold of the in vitro IC50 (95% CI: 135 - 2073).'

#Covid19

medrxiv.org/content/10.1101/20

Folks have mentioned that Twitter is an extremely important space for sharing #protest news across the world and as a result we should keep preserving it despite the takeover.

I get it, I am #Iranian, I have relied heavily on twitter for news sharing re protests in #Iran over the years.

But what you are missing is that those same activists and protesters are MOST vulnerable to the new Twitter regime. Misinformation campaigns will be easy, and #Putin/#China/Islamic republic will use it.

Hello Mastodon! #introduction 👋​

I'm a cognitive neuroscientist 🧠​🔬​💻​ at the psychology department in Leiden, The Netherlands 🇳🇱​🌷​

I research how we make decisions 🔀​ and how our brains change as we age 👵​ (both in 🐁​ and 👩​)

Beyond brains, I care & post about #feminism, #openscience and #climateaction 🌍​

Happy to be here!

"Why don't we share data and code?" Nice and concise infographic about perceived barriers and benefits. Full article: royalsocietypublishing.org/doi

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